| PubMed: | Synthesis and biological evaluation of novel sarsasapogenin derivatives as potential anti-tumor agents. |
| PubMed: | LC-MS(n) characterization of steroidal saponins in Helleborus niger L. roots and their conversion products during fermentation. |
| PubMed: | A monoclonal antibody-based competitive ELISA for the determination of ruscogenin in Chinese traditional medicines and biological samples. |
| PubMed: | The genus Anemarrhena Bunge: A review on ethnopharmacology, phytochemistry and pharmacology. |
| PubMed: | Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells. |
| PubMed: | Sarsasapogenin induces apoptosis via the reactive oxygen species-mediated mitochondrial pathway and ER stress pathway in HeLa cells. |
| PubMed: | Evaluation of anxiolytic-like effect of aqueous extract of asparagus stem in mice. |
| PubMed: | Efficient one-pot synthesis of tigogenin saponins and their antitumor activities. |
| PubMed: | Diacetoxyiodobenzene-mediated synthesis of unnatural furospirostane sapogenins derived from diosgenin and tigogenin. |
| PubMed: | Reversal of dopamine neurons and locomotor ability degeneration in aged rats with smilagenin. |
| PubMed: | Sarsasapogenin Increases Melanin Synthesis via Induction of Tyrosinase and Microphthalmia-Associated Transcription Factor Expression in Melan-a Cells. |
| PubMed: | Smilagenin attenuates beta amyloid (25-35)-induced degeneration of neuronal cells via stimulating the gene expression of brain-derived neurotrophic factor. |
| PubMed: | Regioselective cleavage of 22-oxo-23-spiroketals. Novel cholestanic frameworks with pyranone and cyclopentenone E rings on the side chain. |
| PubMed: | Concise synthesis and antitumor activities of trisaccharide steroidal saponins. |
| PubMed: | A double-blind, placebo-controlled study of traditional Chinese medicine sarsasapogenin added to risperidone in patients with negative symptoms dominated schizophrenia. |
| PubMed: | Hydroxylation of steroids by Fusarium oxysporum, Exophiala jeanselmei and Ceratocystis paradoxa. |
| PubMed: | A novel sarsasapogenin glycoside from Asparagus racemosus elicits protective immune responses against HBsAg. |
| PubMed: | Simultaneous analysis of diosgenin and sarsasapogenin in Asparagus officinalis byproduct by thin-layer chromatography. |
| PubMed: | A sensitive indirect competitive enzyme-linked immunosorbent assay for the detection of sarsasapogenin in rat plasma. |
| PubMed: | Chemical constituents of Asparagus. |
| PubMed: | One unique steroidal sapogenin obtained through the microbial transformation of ruscogenin by Phytophthora cactorum ATCC 32134 and its potential inhibitory effect on tissue factor (TF) procoagulant activity. |
| PubMed: | Role of CREB in the regulatory action of sarsasapogenin on muscarinic M1 receptor density during cell aging. |
| PubMed: | Antiviral activity of Solanum paniculatum extract and constituents. |
| PubMed: | Inhibitory effects of steroidal timosaponins isolated from the rhizomes of Anemarrhena asphodeloides against passive cutaneous anaphylaxis reaction and pruritus. |
| PubMed: | Deacylation reactions of 20-acetyl dinorcholanic lactones and 20,23-diacetyl furost-22-enes. |
| PubMed: | An improved facile method for extraction and determination of steroidal saponins in Tribulus terrestris by focused microwave-assisted extraction coupled with GC-MS. |
| PubMed: | Synthesis of "glycospirostanes" via ring-closing metathesis. |
| PubMed: | Revisiting 23-iodospirostanes. New facts and full characterization. |
| PubMed: | The protective potential of Yucca schidigera (Sarsaponin 30) against nitrite-induced oxidative stress in rats. |
| PubMed: | Timosaponin AIII, a saponin isolated from Anemarrhena asphodeloides, ameliorates learning and memory deficits in mice. |
| PubMed: | Development and validation of a sensitive and rapid non-aqueous LC-ESI-MS/MS method for measurement of diosgenin in the plasma of normal and hyperlipidemic rats: a comparative study. |
| PubMed: | (20S,2''S)-20-[4'-(3''-Hydroxy-2''-methyl-prop-yl)-3'-methylisoxazol-5-yl]-5β-preg-nan-3β,16β-diol. |
| PubMed: | The zwitterion (23'E)-(23R,25S)-23-[1-(oxidoiminio)eth-yl]-5β-spiro-stan-3β-yl acetate. |
| PubMed: | Timosaponin A-III induces autophagy preceding mitochondria-mediated apoptosis in HeLa cancer cells. |
| PubMed: | Rat growth-hormone release stimulators from fenugreek seeds. |
| PubMed: | Steroids from the roots of Asparagus officinalis and their cytotoxic activity. |
| PubMed: | Regulation of M1-receptor mRNA stability by smilagenin and its significance in improving memory of aged rats. |
| PubMed: | The effects of Yucca schidigera and Quillaja saponaria on DNA damage, protein oxidation, lipid peroxidation, and some biochemical parameters in streptozotocin-induced diabetic rats. |
| PubMed: | PYM50028, a novel, orally active, nonpeptide neurotrophic factor inducer, prevents and reverses neuronal damage induced by MPP+ in mesencephalic neurons and by MPTP in a mouse model of Parkinson's disease. |
| PubMed: | Role of glial cell derived neurotrophic factor in the protective effect of smilagenin on rat mesencephalic dopaminergic neurons damaged by MPP+. |
| PubMed: | Mitochondrial ROS burst as an early sign in sarsasapogenin-induced apoptosis in HepG2 cells. |
| PubMed: | Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines. |
| PubMed: | [Studies on accumulation of active ingredients, N, P and K in Anemarrhena asphodeloides]. |
| PubMed: | Inhibition of human rheumatoid arthritis synovial cell survival by hecogenin and tigogenin is associated with increased apoptosis, p38 mitogen-activated protein kinase activity and upregulation of cyclooxygenase-2. |
| PubMed: | [Investigation on the technology of processing Anemarrhena asphodeloides Bge. without hair by water]. |
| PubMed: | Identification of cytotoxic constituents of Narthecium ossifragum using bioassay-guided fractionation. |
| PubMed: | The apoptotic effect of sarsasapogenin from Anemarrhena asphodeloides on HepG2 human hepatoma cells. |
| PubMed: | Tigogenin inhibits adipocytic differentiation and induces osteoblastic differentiation in mouse bone marrow stromal cells. |
| PubMed: | Antidepressant activity of sarsasapogenin from Anemarrhena asphodeloides Bunge (Liliaceae). |
| PubMed: | Antidepressant-like effects of sarsasapogenin from Anemarrhena asphodeloides BUNGE (Liliaceae). |
| PubMed: | Determination of ruscogenin in crude Chinese medicines and biological samples by immunoassay. |
| PubMed: | Steroidal saponins from roots of Asparagus officinalis. |
| PubMed: | A new approach to the pharmacological regulation of memory: Sarsasapogenin improves memory by elevating the low muscarinic acetylcholine receptor density in brains of memory-deficit rat models. |
| PubMed: | New bisfuran derivative from sarsasapogenin. An X-ray and NMR analysis. |
| PubMed: | Structure-function relationship for saponin effects on cell cycle arrest and apoptosis in the human 1547 osteosarcoma cells: a molecular modelling approach of natural molecules structurally close to diosgenin. |
| PubMed: | [Synthesis from tigogenin and antituberculosis activity of some of the derivatives of 5alpha-ketosteroid hydrazones]. |
| PubMed: | Investigation of spectrophotometrically determined substances in Yucca extract by GC/MS, TLC and on-column injection GC. |
| PubMed: | Effect of sarsaponin on ruminal fermentation with particular reference to methane production in vitro. |
| PubMed: | Evidence for essential histidine and dicarboxylic amino-acid residues in the active site of UDP-glucose : solasodine glucosyltransferase from eggplant leaves. |
| PubMed: | Ovine metabolism of lithogenic sapogenins. Synthesis of [2,2,4,4-(2)h(4)]sarsasapogenone, [2,2,4,4-(2)h(4)]sarsasapogenin, and [2,2,4,4-(2)h(4)]episarsasapogenin and evaluation of deuterium retention in a sheep-dosing trial. |
| PubMed: | Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells. |
| PubMed: | Regioselective cleavage of rings E and F in sarsasapogenin. |
| PubMed: | Rumen fermentation and nitrogen balance of lambs fed diets containing plant extracts rich in tannins and saponins, and associated emissions of nitrogen and methane. |
| PubMed: | [Screening of steroidal saponins from the bulbs of Lilium brownii var. colchesteri by combination of high performance liquid chromatography-electrospray ionization mass spectrometry and electron impact mass spectrometry]. |
| PubMed: | [Determination of sarsasapogenin in Anemarrhena asphodeloides Bunge by GC]. |
| PubMed: | Ruminal metabolism in sheep of saponins from Yucca schidigera. |
| PubMed: | Effect of sarsasapogenin and its derivatives on the stimulus coupled responses of human neutrophils. |
| PubMed: | [Determination of sarsasapogenin in "tian dong" by TLCS]. |
| PubMed: | Phospholipids modulate the substrate specificity of soluble UDP-glucose:steroid glucosyltransferase from eggplant leaves. |
| PubMed: | 13C cross-polarization MAS NMR study of some steroidal sapogenins. |
| PubMed: | Ovine metabolism of saponins: evaluation of a method for estimating the ovine uptake of steroidal saponins from Narthecium ossifragum. |
| PubMed: | Microdetermination of diosgenin from fenugreek (Trigonella foenum-graecum) seeds. |
| PubMed: | Spirostanols obtained by cyclization of pseudosaponin derivatives and comparison of anti-platelet agglutination activities of spirostanol glycosides. |
| PubMed: | Isolation of steroidal sapogenins implicated in experimentally induced cholangiopathy of sheep grazing Brachiaria decumbens in Brazil. |
| PubMed: | Influence of tempering on the feeding value of rolled corn in finishing diets for feedlot cattle. |
| PubMed: | Effect of Quillaja saponaria saponins and Yucca schidigera plant extract on growth of Escherichia coli. |
| PubMed: | Microbial transformation of dihydrosarsasapogenin with Mycobacterium sp. |
| PubMed: | Dependence of the 1H NMR chemical shifts of ring F resonances on the orientation of the 27-methyl group of spirostane-type steroidal sapogenins. |
| PubMed: | The ameliorating effect of Yucca schidigera extract on canine and feline faecal aroma. |
| PubMed: | Metabolism of saponins from Narthecium ossifragum--a plant implicated in the aetiology of alveld, a hepatogenous photosensitization of sheep. |
| PubMed: | Anti-inflammatory activity of aqueous extracts and steroidal sapogenins of Agave americana. |
| PubMed: | Steroidal saponins from Smilax officinalis. |
| PubMed: | Influence of yucca extract on ruminal metabolism in cows. |
| PubMed: | An attempt to reproduce crystal-associated cholangitis in lambs in experimental dosing of sarsasapogenin or diosgenin alone and in combination with sporidesmin. |
| PubMed: | Structure-activity relationships of synthetic tigogenyl glycosides. |
| PubMed: | Epi-sarsasapogenin and epi-smilagenin: two sapogenins isolated from the rumen content of sheep intoxicated by Brachiaria decumbens. |
| PubMed: | [Quality of rhizoma Anemarrhenae grown for different periods of time and gathered in different seasons]. |
| PubMed: | Purification of toxic saponins from Narthecium asiaticum Maxim. |
| PubMed: | Cladosporium magnusianum (Jaap) M.B. Ellis is probably not involved in alveld. |
| PubMed: | The reactions of beta- and alpha-pyranose peracetates with PCl5, and utilization of the products to construct sarsasapogenin glycosides. |
| PubMed: | Implication of steroid saponins and sapogenins in the hypocholesterolemic effect of fenugreek. |
| PubMed: | [Steroidal saponins from Asparagus filicinus]. |
| PubMed: | [TLC-densitometric determination of sarsasapogenin in Anemarrhena asphodeloides Bge]. |
| PubMed: | Isolation of a steroidal sapogenin from the bile of a sheep fed Agave lecheguilla. |
| PubMed: | Influence of sarsaponin on growth, feed and nitrogen utilization in growing male rats fed diets with added urea or protein. |
| PubMed: | Effect of feeding Sarsaponin in cattle and swine diets. |
| PubMed: | Effects of alpha- and beta-tigogenin cellobiosides on cholesterol absorption. |
| PubMed: | Effect of steroidal sapogenins on ruminal fermentation and on production of lactating dairy cows. |
| PubMed: | Effects of sarsaponin on digestion and passage rates in cattle fed medium to low concentrate. |
| PubMed: | [Steroidal sapogenins from mildewed Dioscorea collettii Hook. f]. |
| PubMed: | Effects of synthetic glycosides on cholesterol absorption. |
| PubMed: | Steroidal sapogenins; magogenin and cacogenin and their biogenesis to chlorogenin and tigogenin. |