aesculus hippocastanum oil
horse chestnut oil
 
Notes:
None found
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Name: aesculus hippocastanum l. oil
CAS Number: 8053-39-2 
ECHA EC Number: 232-497-7
Category: cosmetic and fragrance agents
 
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Physical Properties:
Food Chemicals Codex Listed: No
Soluble in:
 alcohol
Insoluble in:
 water
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-guinea pig LD50  37 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960.

intravenous-guinea pig LD50  940 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960.

oral-guinea pig LD50  1120 mg/kg
Drugs in Japan Vol. 6, Pg. 398, 1982.

intraperitoneal-mouse LD50  6700 ug/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982.

intraperitoneal-mouse LD50  55 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: PLEURAL THICKENING
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 8, Pg. 45, 1980.

intravenous-mouse LD50  14400 ug/kg
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960.

intravenous-mouse LD50  1377 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960.

oral-mouse LD50  164 mg/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982.

oral-mouse LD50  990 mg/kg
Drugs in Japan Vol. 6, Pg. 398, 1982.

intravenous-rabbit LD50  30 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960.

intravenous-rabbit LD50  400 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960.

oral-rabbit LD50  1530 mg/kg
Drugs in Japan Vol. 6, Pg. 398, 1982.

intraperitoneal-rat LD50  10100 ug/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982.

intraperitoneal-rat LD50  13750 mg/kg
Drugs in Japan Vol. 6, Pg. 399, 1982.

intravenous-rat LD50  62500 ug/kg
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960.

intravenous-rat LD50  1450 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 10, Pg. 263, 1960.

oral-rat LD50  833 mg/kg
Yakkyoku. Pharmacy. Vol. 33, Pg. 335, 1982.

oral-rat LD50  2150 mg/kg
Drugs in Japan Vol. 6, Pg. 398, 1982.

Dermal Toxicity:
subcutaneous-mouse LD50 38500 ug/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982.

subcutaneous-rat LD50 150 mg/kg
Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 13, Pg. 349, 1982.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Recommendation for aesculus hippocastanum oil flavor usage levels up to:
 not for flavor use.
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Safety References:
ClinicalTrials.gov: search
Daily Med: search
AIDS Citations: Search
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 aesculus hippocastanum l. oil
Chemidplus: 0008053392
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References:
 aesculus hippocastanum l. oil
Pubchem (sid): 135344704
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Other Information:
MedlinePlusSupp: View
Wikipedia: View
FAO Doc: BASIC PRINCIPLES OF STEAM DISTILLATION
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 chestnut horse-chestnut
Search Trop  Picture
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Synonyms:
horse chestnut aesculus glabra oil
horse chestnut oil
 hippocastanum vulgare oil
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