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Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 186.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 572.10 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 572.00 °F. TCC ( 299.80 °C. ) (est)
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| logP (o/w): | 2.504 (est) |
| Soluble in: |
| | water, 1.224 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-man TDLo 514 mg/kg/60D- PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE British Medical Journal. Vol. 309, Pg. 929, 1994.
oral-man TDLo 1326 mg/kg/37W KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" Lancet. Vol. 341, Pg. 371, 1993.
intraperitoneal-mouse LD50 500 mg/kg Medicamentos de Actualidad. Vol. 15, Pg. 215, 1979.
oral-mouse LD50 723 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) Kiso to Rinsho. Clinical Report. Vol. 22, Pg. 4293, 1988.
intraperitoneal-rat LD50 505 mg/kg Medicamentos de Actualidad. Vol. 15, Pg. 215, 1979.
oral-rat LD50 1082 mg/kg GASTROINTESTINAL: TUMORS
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Kiso to Rinsho. Clinical Report. Vol. 22, Pg. 4293, 1988.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 1635 mg/kg Drugs in Japan Vol. -, Pg. 1226, 1995.
subcutaneous-rat LD50 1580 mg/kg GASTROINTESTINAL: TUMORS
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Kiso to Rinsho. Clinical Report. Vol. 22, Pg. 4293, 1988.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis |
| Recommendation for bezafibrate usage levels up to: | | | not for fragrance use.
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| Recommendation for bezafibrate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 39042 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 1 |
| | 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid |
| Chemidplus: | 0041859670 |
| RTECS: | UE8755000 for cas# 41859-67-0 |
References:
| | 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 39042 |
| Pubchem (sid): | 135001112 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | azufibrat | | | befibrat | | | bezafibratum | | | bezalande | | | bezapuren | | 2-(p-(2-(p- | chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid | | 2-[4-[2-(4- | chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid | | 2-[p-[2-(p- | chlorobenzamido)ethyl]phenoxy]-2-methylpropionic acid | | 2-[p-[2-p- | chlorobenzamido)ethyl]phenoxy]-2-methylpropionic acid | | 2-{4-[2-(4- | chlorobenzamido)ethyl]phenoxy}-2-methylpropanoic acid | | 2-[4-[2-[(4- | chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl-propanoic acid | | 2-[4-[2-[(4- | chlorobenzoyl)amino]ethyl]phenoxy]-2-methylpropanoic acid | | 2-(4-{2-[(4- | chlorophenyl)carbonylamino]ethyl}phenoxy)-2-methylpropanoic acid | | | difaterol | | | durabezur | | | propanoic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl- | | | propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl- | | | propionic acid, 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl- | | | reducterol | | | sklerofibrat |
Articles:
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