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Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | red-brown powder (est) |
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 497.96 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 475.00 °F. TCC ( 245.90 °C. ) (est)
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| logP (o/w): | 4.312 (est) |
| Soluble in: |
| | water, 0.04758 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Tanshinone I 98%
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| BOC Sciences |
| For experimental / research use only. |
| Tanshinone I 0.96
Odor: characteristic Use: Tanshinone I isolated from the roots of Salvia miltiorrhiza. It can protect against peroxynitrite-induced DNA damage, and hydroxyl radical formation and cytotoxicity, might have implications for Tanshinone I-mediated neuroprotection.
anti-tumor; anti-cancer; |
| Coompo |
| For experimental / research use only. |
| Tanshinone I from Plants ≥96%
Odor: characteristic Use: Tanshinone I significantly inhibited migration, invasion, and gelatinase activity in macrophage-conditioned medium-stimulated CL1-5 cells in vitro and also reduced the tumorigenesis and metastasis in CL1-5-bearing severe combined immunodeficient mice.
Tanshinone I possesses the strongest inhibitory effect on tumor necrosis factor-a (TNF-a)- induced adhesion molecules. Its potential anticoagulant effect should be noted and evaluated. |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Tanshinone I
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| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Tanshinone I ≥97% (HPLC)
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Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis |
| Recommendation for tanshinone usage levels up to: | | | not for fragrance use.
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| Recommendation for tanshinone flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | 1,6-dimethylnaphtho[1,2-g][1]benzofuran-10,11-dione |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 114917 |
| Pubchem (sid): | 135071823 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,6- | dimethyl-phenanthro[1,2-b]furan-10,11-dione | | 1,6- | dimethylnaphtho[1,2-g][1]benzofuran-10,11-dione | | 1,6- | dimethylphenanthro(1,2-b)furan-10,11-dione | | 1,6- | dimethylphenanthro[1,2-b]furan-10,11-dione | | | phenanthro(1,2-b)furan-10,11-dione, 1,6-dimethyl- | | | phenanthro[1,2-b]furan-10,11-dione, 1,6-dimethyl- | | | tanshinon I | | | tanshinone I | | | tanshinone II B | | | tanshinone IIB |
Articles:
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