| PubMed: | Astragaloside IV stimulates angiogenesis and increases nitric oxide accumulation via JAK2/STAT3 and ERK1/2 pathway. |
| PubMed: | Astragaloside IV attenuates experimental autoimmune encephalomyelitis of mice by counteracting oxidative stress at multiple levels. |
| PubMed: | Astragalus injection protects cerebral ischemic injury by inhibiting neuronal apoptosis and the expression of JNK3 after cerebral ischemia reperfusion in rats. |
| PubMed: | Identification of multiple ingredients for a Traditional Chinese Medicine preparation (bu-yang-huan-wu-tang) by liquid chromatography coupled with tandem mass spectrometry. |
| PubMed: | Pharmacological effects of Astragaloside IV: a literature review. |
| PubMed: | Pharmacokinetics and tolerance of toal astragalosides after intravenous infusion of astragalosides injection in healthy Chinese volunteers. |
| PubMed: | Astragaloside IV reduces cerebral edema post-ischemia/reperfusion correlating the suppression of MMP-9 and AQP4. |
| PubMed: | Can Hedysari Radix replace Astragali Radix in Danggui Buxue Tang, a Chinese herbal decoction for woman aliment? |
| PubMed: | [Protective effect and mechanism of astragaloside IV on oxidative stress injury of mesangial cells]. |
| PubMed: | [Experimental studies on pharmacokinetics of three components in Buyanghuanwu injection on base of total quantum statistical moment]. |
| PubMed: | Synergistic promotion of blood vessel regeneration by astragaloside IV and ferulic acid from electrospun fibrous mats. |
| PubMed: | Genetic and pharmacological inhibition of Rheb1-mTORC1 signaling exerts cardioprotection against adverse cardiac remodeling in mice. |
| PubMed: | Effects of astragaloside IV on action potentials and ionic currents in guinea-pig ventricular myocytes. |
| PubMed: | Astragaloside IV-loaded nanoparticle-enriched hydrogel induces wound healing and anti-scar activity through topical delivery. |
| PubMed: | Astragaloside IV suppresses collagen production of activated hepatic stellate cells via oxidative stress-mediated p38 MAPK pathway. |
| PubMed: | Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression. |
| PubMed: | Astragaloside content in the periderm, cortex, and xylem of Astragalus membranaceus root. |
| PubMed: | Astragaloside IV prevents acute kidney injury in two rodent models by inhibiting oxidative stress and apoptosis pathways. |
| PubMed: | The experimental study of Astragalus membranaceus on meridian tropsim: the distribution study of astragaloside IV in rat tissues. |
| PubMed: | Astragaloside IV inhibited the activity of CYP1A2 in liver microsomes and influenced theophylline pharmacokinetics in rats. |
| PubMed: | [Protective effects of astragaloside IV on high-glucose-induced damage of retinal ganglion cells]. |
| PubMed: | Astragaloside IV inhibits oxidative stress-induced mitochondrial permeability transition pore opening by inactivating GSK-3β via nitric oxide in H9c2 cardiac cells. |
| PubMed: | Astragaloside IV attenuates Toll-like receptor 4 expression via NF-κB pathway under high glucose condition in mesenchymal stem cells. |
| PubMed: | Therapeutic effects of astragaloside IV on myocardial injuries: multi-target identification and network analysis. |
| PubMed: | The effect of Astragaloside IV on immune function of regulatory T cell mediated by high mobility group box 1 protein in vitro. |
| PubMed: | Tanshinone IIA and astragaloside IV promote the migration of mesenchymal stem cells by up-regulation of CXCR4. |
| PubMed: | Astragaloside IV alleviates hypoxia/reoxygenation-induced neonatal rat cardiomyocyte injury via the protein kinase a pathway. |
| PubMed: | Astragaloside IV, a novel antioxidant, prevents glucose-induced podocyte apoptosis in vitro and in vivo. |
| PubMed: | [Inhibitory effects of astragaloside IV on cytochrome P450 enzyme of rat liver microsomes]. |
| PubMed: | Topical astragaloside IV-releasing hydrogel improves healing of skin wounds in vivo. |
| PubMed: | Pharmacokinetic evidence on the contribution of intestinal bacterial conversion to beneficial effects of astragaloside IV, a marker compound of astragali radix, in traditional oral use of the herb. |
| PubMed: | Effects of astragaloside IV on eosinophil activation induced by house dust mite allergen. |
| PubMed: | Astragaloside IV regulates expression of ATP-sensitive potassium channel subunits after ischemia-reperfusion in rat ventricular cardiomyocytes. |
| PubMed: | Astragaloside IV protects against focal cerebral ischemia/reperfusion injury correlating to suppression of neutrophils adhesion-related molecules. |
| PubMed: | [Effects of astragaloside IV on the expressions of transforming growth factor-β1 and thymic stromal lymphopoietin in a murine model of asthma]. |
| PubMed: | Astragaloside IV prevents MPP⁺-induced SH-SY5Y cell death via the inhibition of Bax-mediated pathways and ROS production. |
| PubMed: | Astragaloside IV inhibits apoptotic cell death in the guinea pig cochlea exposed to impulse noise. |
| PubMed: | Determination of astragalin and astragaloside content in Radix Astragali using high-performance liquid chromatography coupled with pulsed amperometric detection. |
| PubMed: | Synergistic protective effect of astragaloside IV-tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia. |
| PubMed: | Pro-angiogenic activity of astragaloside IV in HUVECs in vitro and zebrafish in vivo. |
| PubMed: | [Immunoregulatory mechanisms of an optimal Chinese herbal monomer compound in mice with allergic rhinitis]. |
| PubMed: | The healing and anti-scar effects of astragaloside IV on the wound repair in vitro and in vivo. |
| PubMed: | [Effect of ERK1/2 signaling pathway on astragaloside IV protects H9c2 cells against H2O2-induced oxidative injury]. |
| PubMed: | Astragaloside IV attenuates complement membranous attack complex induced podocyte injury through the MAPK pathway. |
| PubMed: | Astragaloside IV and cycloastragenol stimulate the phosphorylation of extracellular signal-regulated protein kinase in multiple cell types. |
| PubMed: | [Determination of astragaloside IV of eight area in Astragali Radix is by HPLC-ELSD internal standard method]. |
| PubMed: | Protective effect of astragaloside IV against matrix metalloproteinase-1 expression in ultraviolet-irradiated human dermal fibroblasts. |
| PubMed: | [Effects of astragaloside on IGF-1 and associated protein expression in mice with acute viral myocarditis]. |
| PubMed: | Ultrasonic-assisted liquid-liquid extraction and HILIC-ELSD analysis of ginsenoside Rb(1), astragaloside IV and dulcitol in sugar-free "Fufangfufangteng Heji". |
| PubMed: | [Effect of astragaloside against the oxidative damage on endothelial cells]. |
| PubMed: | Effect comparison of different formulation of Dang-Gui-Bu-Xu-Tang on myelosuppression mouse. |
| PubMed: | [Simultaneous determination of five glycosides in Aidi injection by RP-HPLC-ELSD]. |
| PubMed: | Astragaloside IV protects against ischemia reperfusion in a murine model of orthotopic liver transplantation. |
| PubMed: | Chuanxiongzine-astragaloside IV decreases IL-1β and Caspase-3 gene expressions in rat brain damaged by cerebral ischemia/reperfusion: a study of real-time quantitative PCR assay. |
| PubMed: | [Regulation of Vitreoscilla hemoglobin on biosynthesis of astragaloside IV]. |
| PubMed: | Astragaloside IV stimulates angiogenesis and increases hypoxia-inducible factor-1α accumulation via phosphatidylinositol 3-kinase/Akt pathway. |
| PubMed: | Astragaloside IV improves metabolic syndrome and endothelium dysfunction in fructose-fed rats. |
| PubMed: | Astragaloside IV attenuates impulse noise-induced trauma in guinea pig. |
| PubMed: | Astragaloside IV inhibits adenovirus replication and apoptosis in A549 cells in vitro. |
| PubMed: | Protective effects of astragaloside against ultraviolet A-induced photoaging in human fibroblasts. |
| PubMed: | The osteogenetic effect of astragaloside IV with centrifugating pressure on the OCT-1 cells. |
| PubMed: | Astragaloside IV attenuates myocardial fibrosis by inhibiting TGF-β1 signaling in coxsackievirus B3-induced cardiomyopathy. |
| PubMed: | [Protective effect of astragalosides on anoxia/reoxygenation injury of hippocampal neuron]. |
| PubMed: | Astragaloside IV synergizes with ferulic acid to inhibit renal tubulointerstitial fibrosis in rats with obstructive nephropathy. |
| PubMed: | The known immunologically active components of Astragalus account for only a small proportion of the immunological adjuvant activity when combined with conjugate vaccines. |
| PubMed: | Comparative investigations on the protective effects of rhodioside, ciwujianoside-B and astragaloside IV on radiation injuries of the hematopoietic system in mice. |
| PubMed: | Effects of astragaloside IV on IFN-gamma level and prolonged airway dysfunction in a murine model of chronic asthma. |
| PubMed: | Effect of astragaloside IV on the general and peripartum reproductive toxicity in Sprague-Dawley rats. |
| PubMed: | [Morphological investigation of the protective effect of astragaloside preconditioning against ischemia-reperfusion lung injury in rats]. |
| PubMed: | [Transformation of astragaloside IV in bidirectional solid fermenting of Astragalus membranaceus]. |
| PubMed: | Preparative enrichment and separation of astragalosides from Radix Astragali extracts using macroporous resins. |
| PubMed: | [Study on preventative and curative effects of astragaloside (AST) on mice memory impairment and expression of amyloid precursor protein and beta secretase mRNA induced by dexamethasone]. |
| PubMed: | Protective effect of astragaloside on focal cerebral ischemia/reperfusion injury in rats. |
| PubMed: | [Stem cell factor secretion by bone mesenchymal stem cells stimulated with astragaloside IV]. |
| PubMed: | Astragaloside IV improves homocysteine-induced acute phase endothelial dysfunction via antioxidation. |
| PubMed: | [Inhibitory effect on activated renin-angiotensin system by astragaloside IV in rats with pressure-overload induced cardiac hypertrophy]. |
| PubMed: | Cigarette smoke enhances {beta}-defensin 2 expression in rat airways via nuclear factor-{kappa}B activation. |
| PubMed: | Proteomic characterization of the cellular response to chemopreventive triterpenoid astragaloside IV in human hepatocellular carcinoma cell line HepG2. |
| PubMed: | Effects of cycloartane saponins from hairy roots of Astragalus membranaceus Bge., on human tumor cell targets. |
| PubMed: | Ligustilide suppresses the biological properties of Danggui Buxue Tang: a Chinese herbal decoction composed of radix astragali and radix angelica sinensis. |
| PubMed: | Astragalosides isolated from the root of astragalus radix inhibit the formation of advanced glycation end products. |
| PubMed: | Effect of astragaloside IV on hepatic glucose-regulating enzymes in diabetic mice induced by a high-fat diet and streptozotocin. |
| PubMed: | Protective effects of astragaloside IV on porcine-serum-induced hepatic fibrosis in rats and in vitro effects on hepatic stellate cells. |
| PubMed: | Neuroprotective effects of Astragaloside IV in 6-hydroxydopamine-treated primary nigral cell culture. |
| PubMed: | [Study on the determination method of the astragaloside IV in health food]. |
| PubMed: | Astragaloside IV attenuates cerebral ischemia-reperfusion-induced increase in permeability of the blood-brain barrier in rats. |
| PubMed: | Effect of astragaloside IV on the embryo-fetal development of Sprague-Dawley rats and New Zealand White rabbits. |
| PubMed: | Anti-hepatitis B virus activities of astragaloside IV isolated from radix Astragali. |
| PubMed: | Astragaloside IV attenuates hypoxia-induced cardiomyocyte damage in rats by upregulating superoxide dismutase-1 levels. |
| PubMed: | Astragaloside IV attenuates lipolysis and improves insulin resistance induced by TNFalpha in 3T3-L1 adipocytes. |
| PubMed: | [Study on absorption kinetics of astragaloside IV in rats intestines]. |
| PubMed: | Astragaloside IV improves high glucose-induced podocyte adhesion dysfunction via alpha3beta1 integrin upregulation and integrin-linked kinase inhibition. |
| PubMed: | Inhibitory effects of astragaloside IV on ovalbumin-induced chronic experimental asthma. |
| PubMed: | Astragaloside IV inhibits proliferation and promotes apoptosis in rat vascular smooth muscle cells under high glucose concentration in vitro. |
| PubMed: | [Determination of the total content of astragaloside IV in Radix Astragali]. |
| PubMed: | [Amic solution hydrolysis for improving content of astragaloside IV in extract of Radix Astragali]. |
| PubMed: | Astragaloside IV improved intracellular calcium handling in hypoxia-reoxygenated cardiomyocytes via the sarcoplasmic reticulum Ca-ATPase. |
| PubMed: | Simultaneous determination of calycosin-7-O-beta-D-glucoside, ononin, astragaloside IV, astragaloside I and ferulic acid in rat plasma after oral administration of Danggui Buxue Tang extract for their pharmacokinetic studies by liquid chromatography-mass spectrometry. |
| PubMed: | [Effects of AST and ASI on metabolism of free radical in senescent rats treated by HC]. |
| PubMed: | Aqueous extract of Astragali Radix induces human natriuresis through enhancement of renal response to atrial natriuretic peptide. |
| PubMed: | Astragaloside IV inhibits spontaneous synaptic transmission and synchronized Ca2+ oscillations on hippocampal neurons. |
| PubMed: | [Astragalus polysaccharides and astragalosides regulate cytokine secretion in LX-2 cell line]. |
| PubMed: | [Investigation on one-pot extraction of active ingredient group from Yupingfeng powder by HPLC]. |
| PubMed: | [Protective effects of Astragaloside and Quercetin on rat myocardial cells after hypoxia]. |
| PubMed: | [Effect of astragaloside on myocardial fibrosis in chronic myocarditis]. |
| PubMed: | Pharmacokinetics of astragaloside iv in beagle dogs. |
| PubMed: | Simultaneous characterization of isoflavonoids and astragalosides in two Astragalus species by high-performance liquid chromatography coupled with atmospheric pressure chemical ionization tandem mass spectrometry. |
| PubMed: | Determination of seventeen main flavonoids and saponins in the medicinal plant Huang-qi (Radix astragali) by HPLC-DAD-ELSD. |
| PubMed: | [Fundamentally study on mathematical kinetic model of component extraction from FTCM]. |
| PubMed: | Development of microwave assisted extraction for the simultaneous determination of isoflavonoids and saponins in radix astragali by high performance liquid chromatography. |
| PubMed: | Modification of alterations in cardiac function and sarcoplasmic reticulum by astragaloside IV in myocardial injury in vivo. |
| PubMed: | Effect of astragaloside on cardiomyocyte apoptosis in murine coxsackievirus B3 myocarditis. |
| PubMed: | Mechanisms underlying vasorelaxant action of astragaloside IV in isolated rat aortic rings. |
| PubMed: | Effects of Astragalus polysaccharides and astragalosides on the phagocytosis of Mycobacterium tuberculosis by macrophages. |
| PubMed: | [The effect of icariin and astragalosid I on the proliferation and differentiation of bone marrow stromal cells]. |
| PubMed: | [Anti-apoptosis effect of astragaloside on adriamycin induced rat's cardiotoxicity]. |
| PubMed: | [Study on fingerprints of astragalosides injection by HPLC-ELSD]. |
| PubMed: | [Determination of three constituents in Radix Astragali by HPLC-MS]. |
| PubMed: | Simultaneous analysis of seven astragalosides in Radix Astragali and related preparations by liquid chromatography coupled with electrospray ionization time-of-flight mass spectrometry. |
| PubMed: | Promotion of axonal maturation and prevention of memory loss in mice by extracts of Astragalus mongholicus. |
| PubMed: | Inhibitory effects of astragaloside IV on diabetic peripheral neuropathy in rats. |
| PubMed: | Astragaloside IV dilates aortic vessels from normal and spontaneously hypertensive rats through endothelium-dependent and endothelium-independent ways. |
| PubMed: | Absorption enhancement study of astragaloside IV based on its transport mechanism in caco-2 cells. |
| PubMed: | Astragaloside IV improved barrier dysfunction induced by acute high glucose in human umbilical vein endothelial cells. |
| PubMed: | Chemical and biological assessment of a chinese herbal decoction containing Radix Astragali and Radix Angelicae Sinensis: Determination of drug ratio in having optimized properties. |
| PubMed: | Preclinical pharmacokinetics and tissue distribution of a natural cardioprotective agent astragaloside IV in rats and dogs. |
| PubMed: | Astragaloside IV exerts antiviral effects against coxsackievirus B3 by upregulating interferon-gamma. |
| PubMed: | Astragaloside IV from Astragalus membranaceus shows cardioprotection during myocardial ischemia in vivo and in vitro. |
| PubMed: | Pharmacokinetics of Astragaloside IV in rats by liquid chromatography coupled with tandem mass spectrometry. |
| PubMed: | Effects of astragaloside IV on pathogenesis of metabolic syndrome in vitro. |
| PubMed: | [Study on new extraction technology of astragaloside IV]. |
| PubMed: | The role of astragaloside in regeneration of the peripheral nerve system. |
| PubMed: | Sensitive and selective liquid chromatography-electrospray ionisation-mass spectrometry analysis of astragaloside-IV in rat plasma. |
| PubMed: | Gastroprotective effect of Astragaloside IV: role of prostaglandins, sulfhydryls and nitric oxide. |
| PubMed: | Quantitation of astragaloside IV in rat plasma by liquid chromatography-tandem mass spectrometry. |
| PubMed: | Quantitative determination of Astragaloside IV, a natural product with cardioprotective activity, in plasma, urine and other biological samples by HPLC coupled with tandem mass spectrometry. |
| PubMed: | Separation of compounds interacting with liposome membrane in combined prescription of traditional Chinese medicines with immobilized liposome chromatography. |
| PubMed: | Effect of astragalosides on intracellular calcium overload in cultured cardiac myocytes of neonatal rats. |
| PubMed: | [Studies on chromatography fingerprint of huangqi by HPLC]. |
| PubMed: | Transport and bioavailability studies of astragaloside IV, an active ingredient in Radix Astragali. |
| PubMed: | [Effect of astrgaloside IV on the long-term consequences of renal ischemia-reperfusion injury in rat]. |
| PubMed: | Astragaloside IV protects against ischemic brain injury in a murine model of transient focal ischemia. |
| PubMed: | Determination of Astragaloside IV in rat plasma by liquid chromatography electrospray ionization mass spectrometry. |
| PubMed: | Astragaloside IV and polysaccharide production by hairy roots of Astragalus membranaceus in bioreactors. |
| PubMed: | Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression. |
| PubMed: | Determination of serum astragaloside in rats fed with Buyanghuanwu dicoction using solidphase extraction, chemical derivatization and fluorospectrophotometry. |
| PubMed: | [Scavenging effects of Astragalus and Gynostemma pentaphyllum with its product on O2-. and .OH]. |
| PubMed: | [Effects of components isolated from Astragalus membranaceus Bunge on cardiac function injured by myocardial ischemia reperfusion in rats]. |
| PubMed: | Effects of astragaloside IV on myocardial calcium transport and cardiac function in ischemic rats. |
| PubMed: | [Determination of astragaloside IV in radix Astragali by HPLC with evaporative light scattering detector]. |
| PubMed: | Effect of astragaloside IV on T, B lymphocyte proliferation and peritoneal macrophage function in mice. |
| PubMed: | Antinociceptive effect of astragalosides and its mechanism of action. |
| PubMed: | Determination of astragaloside IV in Radix astragali (Astragalus membranaceus var. monghulicus) using high-performance liquid chromatography with evaporative light-scattering detection. |
| PubMed: | [Experimental studies on the quality of ostracean powder]. |
| PubMed: | [A study on processing of the root of Astragalus membranaceus Bge. by HPLC]. |
| PubMed: | A precolumn derivatization high-performance liquid chromatographic method with improved sensitivity and specificity for the determination of astragaloside IV in Radix Astragali. |
| PubMed: | Regulation of the fibrinolytic potential of cultured human umbilical vein endothelial cells: astragaloside IV downregulates plasminogen activator inhibitor-1 and upregulates tissue-type plasminogen activator expression. |
| PubMed: | [Nuclear cardiology study on effective ingredients of Astragalus membranaceus in treating heart failure]. |
| PubMed: | [A new method for qualitative determination of astragaloside]. |
| PubMed: | [Comparative study of the effect of cycloartane and cardiac glycosides on various parameters of myocardial metabolism in animals]. |
| PubMed: | [Effects of astragalus (ASI, SK) on experimental liver injury]. |
| PubMed: | [Recent development of chemical studies on some medicinal plants of Astragalus spp]. |
| PubMed: | [Quantitative determination of astragaloside A in Astragalus membranaceus]. |