hirudin
L-glutamine, glycyl-D-a-aspartyl-L-phenylalanyl-L-a-glutamyl-L-a-glutamyl-L-alloisoleucyl-L-prolyl-D-a-glutamyl-L-a-glutamyl-L-tyrosyl-L-leucyl-
 
Notes:
None found
Synonyms   Articles   Notes   Search
CAS Number: 113274-56-9Picture of molecule3D/inchi
Nikkaji Web: J378.864D
XlogP3-AA: -4.50 (est)
Molecular Weight: 1468.53821000
Formula: C66 H93 N13 O25
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
PubMed: Search
NCBI: Search
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Appearance: white fine powder (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 1913.60 °C. @ 760.00 mm Hg (est)
Flash Point: 2032.00 °F. TCC ( 1111.10 °C. ) (est)
logP (o/w): -0.190 (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
 None found
Synonyms   Articles   Notes   Search   Top
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: natural substances and extractives
Recommendation for hirudin usage levels up to:
 not for fragrance use.
 
Recommendation for hirudin flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Synonyms   Articles   Notes   Search   Top
References:
NIST Chemistry WebBook: Search Inchi
Pubchem (sid): 277335945
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
HMDB (The Human Metabolome Database): Search
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
L-glutamine, glycyl-D-a-aspartyl-L-phenylalanyl-L-a-glutamyl-L-a-glutamyl-L-alloisoleucyl-L-prolyl-D-a-glutamyl-L-a-glutamyl-L-tyrosyl-L-leucyl-
 glycyl-D-a-aspartyl-L-phenylalanyl-L-a-glutamyl-L-a-glutamyl-L-alloisoleucyl-L-prolyl-D-a-glutamyl-L-a-glutamyl-L-tyrosyl-L-leucyl-L-glutamine
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Pharmacokinetics study of recombinant hirudin in the plasma of rats using chromogenic substrate, ELISA, and radioisotope assays.
PubMed: New oral anticoagulants: comparative pharmacology with vitamin K antagonists.
PubMed: Use of oil bodies and oleosins in recombinant protein production and other biotechnological applications.
PubMed: Brave new world: the current and future use of novel anticoagulants.
PubMed: Expression and intein-mediated purification of novel staphylokinase SakSTAR with reduced immunogenicity and antiplatelet and antithrombin activation.
PubMed: Novel method of expression and purification of hirudin based on pBAD TOPO, pTYB12 vectors and gene synthesis.
PubMed: Lepirudin: a bivalent direct thrombin inhibitor for anticoagulation therapy.
PubMed: Current anticoagulant therapy--unmet clinical needs.
PubMed: Coexpression of BiP increased antithrombotic hirudin production in recombinant Saccharomyces cerevisiae.
PubMed: Selective inhibition of coagulation factors: advances in antithrombotic therapy.
PubMed: New drugs 2002. Part II.
PubMed: Bivalirudin: a direct thrombin inhibitor.
PubMed: Current status of the anticoagulant hirudin: its biotechnological production and clinical practice.
PubMed: Cardiovascular drug highlight: hirudin.
PubMed: Use of recombinant hirudin in heparin-induced thrombocytopenia and thrombosis (HITT) and renal failure--a case report.
PubMed: Effects of methanol on expression of an anticoagulant hirudin in recombinant Hansenula polymorpha.
PubMed: From the Food and Drug Administration.
PubMed: Enhanced production of anticoagulant hirudin in recombinant Saccharomyces cerevisiae by chromosomal delta-integration.
PubMed: FDA panel votes against approval for bivalirudin.
PubMed: Therapy for patients with heparin-induced thrombocytopenia marketed.
PubMed: Separation of r-hirudin from similar substances by capillary electrophoresis.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2021 Perflavory ™ Disclaimer Privacy Policy