dimethomorph
(2Z)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-(4-morpholinyl)-2-propen-1-one
 
Notes:
None found
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      Product(s):
      110488-70-5 Dimethomorph 95%
      Dimethomorph can be used as a fungicide in agriculture. Agricultural fungicide.
       
       
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CAS Number: 110488-70-5Picture of molecule3D/inchi
FDA UNII: 3EXL2158GV
Beilstein Number: 8794474
MDL: MFCD01632781
XlogP3-AA: 3.90 (est)
Molecular Weight: 387.86214000
Formula: C21 H22 Cl N O4
NMR Predictor: Predict (works with chrome or firefox)
Category: herbicides / pesticides
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: 148.00 °C. @ 760.00 mm Hg
Boiling Point: 584.90 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 7.300000 mmHg @ 7.30 °C. (est)
Flash Point: 586.00 °F. TCC ( 307.50 °C. ) (est)
logP (o/w): 2.680
Soluble in:
 water, 18.72 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
BOC Sciences
For experimental / research use only.
Dimethomorph 95%
Odor: characteristic
Use: Dimethomorph can be used as a fungicide in agriculture. Agricultural fungicide.
Santa Cruz Biotechnology
For experimental / research use only.
Dimethomorph
Sigma-Aldrich
For experimental / research use only.
Dimethomorph PESTANAL®, analytical standard
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Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-duck LD50  > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 296, 1991.

oral-mouse LD50  > 5000 mg/kg
Pesticide Manual. Vol. 9, Pg. 296, 1991.

oral-rat LD50  3900 mg/kg
Pesticide Manual. Vol. 9, Pg. 296, 1991.

Dermal Toxicity:
skin-rat LD50 > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 296, 1991.

Inhalation Toxicity:
inhalation-mammal (species unspecified) LC50 > 4200 mg/m3
Pesticide Manual. Vol. 9, Pg. 296, 1991.

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Safety in Use Information:
Category: herbicides / pesticides
Recommendation for dimethomorph usage levels up to:
 not for fragrance use.
 
Recommendation for dimethomorph flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Reasoned opinion on the modification of the existing MRLs for dimethomorph in seeds of spices and caraway
View page or View pdf
Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf
Modification of the existing maximum residue levels (MRLs) for dimethomorph in various crops
View page or View pdf
Setting of import tolerance for dimethomorph in papaya
View page or View pdf
Evaluation of confirmatory data following the Article 12 MRL review for dimethomorph
View page or View pdf
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5463781
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 (Z)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one
Chemidplus: 0110488705
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References:
 (Z)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 5463781
Pubchem (sid): 135042781
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Formulations/Preparations:
•formulation types: dispersible concentrate; wettable powder; water dispersible granules •composition: (e) isomer to (z) isomer ratio is 1:1. •(dimethomorph +) mancozeb; dithianon; copper compounds; fentin hydroxide
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
(2Z)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-(4-morpholinyl)-2-propen-1-one
(2Z)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-(morpholin-4-yl)prop-2-en-1-one
(Z)-3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-morpholin-4-ylprop-2-en-1-one
4-(3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)acryloyl)morpholine
2-propen-1-one, 3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-(4-morpholinyl)-, (2Z)-
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Articles:
PubMed: Determination of fungicides in white grape bagasse by pressurized liquid extraction and gas chromatography tandem mass spectrometry.
PubMed: Efficacy of combined formulations of fungicides with different modes of action in controlling botrytis gray mold disease in chickpea.
PubMed: Influence of new generation fungicides on Saccharomyces cerevisiae growth, grape must fermentation and aroma biosynthesis.
PubMed: Environmental monitoring of pesticide residues from farms at a neighbouring primary and pre-school in the Western Cape in South Africa.
PubMed: Multiresidue pesticide analysis of botanical dietary supplements using salt-out acetonitrile extraction, solid-phase extraction cleanup column, and gas chromatography-triple quadrupole mass spectrometry.
PubMed: Pesticide flow analysis to assess human exposure in greenhouse flower production in Colombia.
PubMed: Simultaneous effects of two fungicides (copper and dimethomorph) on their phytoremediation using Lemna minor.
PubMed: Heterogeneous ozonolysis of folpet and dimethomorph: a kinetic and mechanistic study.
PubMed: Finding of pesticides in fashionable fruit juices by LC-MS/MS and GC-MS/MS.
PubMed: Resistance to the novel fungicide pyrimorph in Phytophthora capsici: risk assessment and detection of point mutations in CesA3 that confer resistance.
PubMed: Influence of molecular mass of lignosulfonates on the resulting surface charges of solid particles.
PubMed: Competitive androgen receptor antagonism as a factor determining the predictability of cumulative antiandrogenic effects of widely used pesticides.
PubMed: Behavior of mixed formulation of metalaxyl and dimethomorph in grape and soil under field conditions.
PubMed: Assessing the risk that Phytophthora melonis can develop a point mutation (V1109L) in CesA3 conferring resistance to carboxylic acid amide fungicides.
PubMed: Toxicity of metalaxyl, azoxystrobin, dimethomorph, cymoxanil, zoxamide and mancozeb to Phytophthora infestans isolates from Serbia.
PubMed: [Rapid determination of 6 pesticide residues in tomato paste by ultra performance liquid chromatography-tandem mass spectrometry].
PubMed: Determination of sixteen pesticides in peppers using high-performance liquid chromatography/mass spectrometry.
PubMed: Studies on the supramolecular interaction between dimethomorph and disulfide linked β-cyclodextrin dimer by spectrofluorimetry and its analytical application.
PubMed: Dissipation and residue of dimethomorph in pepper and soil under field conditions.
PubMed: Removal of pesticide mixtures in a stormwater wetland collecting runoff from a vineyard catchment.
PubMed: Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens.
PubMed: Enzymatic basis for fungicide removal by Elodea canadensis.
PubMed: Baseline sensitivity and resistance-risk assessment of Phytophthora capsici to iprovalicarb.
PubMed: A quantitative review of fungicide efficacy for managing downy mildew in cucurbits.
PubMed: Antifungal activity of the osthol derivative JS-B against Phytophthora capsici.
PubMed: Different responses of E:Z-isomers of pesticides in liquid chromatography-electrospray ionization-mass spectrometry.
PubMed: Synthesis and biological activity of some novel trifluoromethyl-substituted 1,2,4-triazole and bis(1,2,4-triazole) Mannich bases containing piperazine rings.
PubMed: Generation and characterization of isolates of Peronophythora litchii resistant to carboxylic acid amide fungicides.
PubMed: Fungicides and herbicide removal in Scenedesmus cell suspensions.
PubMed: Residue analysis of multi-class pesticides in watermelon by LC-MS/MS.
PubMed: Influence of initial pesticide concentrations and plant population density on dimethomorph toxicity and removal by two duckweed species.
PubMed: Fate of vinclozolin, thiabendazole and dimethomorph during storage, handling and forcing of chicory.
PubMed: Phytoremediation of fungicides by aquatic macrophytes: toxicity and removal rate.
PubMed: Antifungal activity of CHE-23C, a dimeric sesquiterpene from Chloranthus henryi.
PubMed: Multiresidue analysis of pesticides with hydrolyzable functionality in cooked vegetables by liquid chromatography tandem mass spectrometry.
PubMed: Effect of additives in aqueous formulation on the foliar uptake of dimethomorph by cucumbers.
PubMed: Toxicity of copper/dimethomorph combination for Lemna minor and depuration of the fungicides by aquatic plant.
PubMed: Commercial Fungicide Formulations Induce In Vitro Oospore Formation and Phenotypic Change in Mating Type in Phytophthora infestans.
PubMed: Differential Activity of Carboxylic Acid Amide Fungicides Against Various Developmental Stages of Phytophthora infestans.
PubMed: Selection for Fungicide Resistance Within a Growing Season in Field Populations of Phytophthora infestans at the Center of Origin.
PubMed: Method development for the determination of selected pesticides on tobacco by high-performance liquid chromatography-electrospray ionisation-tandem mass spectrometry.
PubMed: Assessing the risk of resistance in Pseudoperonospora cubensis to the fungicide flumorph in vitro.
PubMed: Toxicity and removal of pesticides by selected aquatic plants.
PubMed: Assessment of pesticide susceptibility for Typhlodromus exhilaratus and Typhlodromus phialatus strains (Acari: Phytoseiidae) from vineyards in the south of France.
PubMed: Resistance Induction and Enhanced Tuber Production by Pre-inoculation with Bacterial Strains in Potato Plants against Phytophthora infestans.
PubMed: Investigating the role of ABC transporters in multifungicide insensitivity in Phytophthora infestans.
PubMed: Multiresidue determination of pesticides in malt beverages by capillary gas chromatography with mass spectrometry and selected ion monitoring.
PubMed: Application of liquid chromatography with electrospray tandem mass spectrometry to the determination of a new generation of pesticides in processed fruits and vegetables.
PubMed: Detection of resistance to fungicides, mating types and fitness of Phytophthora infestans in Hebei, China.
PubMed: Method development and fate determination of pesticide-treated hops and their subsequent usage in the production of beer.
PubMed: Laboratory studies to assess the risk of development of resistance to zoxamide.
PubMed: Gas chromatographic-mass spectrometric method for the analysis of dimethomorph fungicide in dried hops.
PubMed: Applications of capillary electrochromatography analysis for formulated pesticide products.
PubMed: Toxicological evaluation of dimethomorph: basis for assessment of risks from dietary exposure.
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