Articles:
matridin-15-one
Notes:
alkaloid from sophora flavescens with anthelmintic activity.
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| CAS Number: | 519-02-8 |  3D/inchi
|
| FDA UNII: | N390W430AC | |
| Beilstein Number: | 0085851 | |
| MDL: | MFCD00210527 | |
| XlogP3-AA: | 1.60 (est) | |
| Molecular Weight: | 248.36948000 | |
| Formula: | C15 H24 N2 O | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: antioxidants
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 76.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 396.00 to 397.00 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 343.00 °F. TCC ( 172.70 °C. ) (est) |
| logP (o/w): | 1.440 (est) |
| Soluble in: | |
| water, 831.5 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
antioxidants skin conditioning |
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Matrine 98% |
| AuNutra® Industries |
| Matrine P.E. |
| BOC Sciences |
| For experimental / research use only. |
| Matrine >98%
Odor: characteristic Use: Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist. |
| Coompo |
| For experimental / research use only. |
| Matrine from Plants ≥95%
Odor: characteristic Use: Matrine has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor and µ-receptor agonist.
Matrine possesses strong antitumor activities in vitro and in vivo. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine's antitumor activities.
The main clinical applications are treatment of people with cancer, viral hepatitis, cardiac diseases (such as viral myocarditis), and skin diseases (such as psoriasis and eczema). |
| Glentham Life Sciences |
| Matrine |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Matrine ≥98% |
| Shaanxi Haokang Bio-technology |
| Sophorae Flavescentis Extract (2.5% Matrine) |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Matrine |
| TCI AMERICA |
| For experimental / research use only. |
| Matrine >98.0%(GC)(T) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intraperitoneal-rat LD50 125 mg/kg Chemical and Pharmaceutical Bulletin. Vol. 18, Pg. 2555, 1970. intravenous-mouse LD50 64.85 mg/kg Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992. intraperitoneal-mouse LD50 150 mg/kg Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 18, Pg. 214, 1987. intramuscular-mouse LD50 74150 ug/kg Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992. intravenous-mouse LD50 64850 ug/kg Zhongguo Yaoxue Zazhi. Chinese Pharmacuetical Journal. Vol. 27, Pg. 201, 1992. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | antioxidants | ||
| Recommendation for matrine usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for matrine flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 638232 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| Chemidplus: | 0000519028 |
| RTECS: | OQ1754000 for cas# 519-02-8 |
References:
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 638232 |
| Pubchem (sid): | 135048634 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| HMDB (The Human Metabolome Database): | Search |
| Export Tariff Code: | 2933.99.9700 |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| sophora flavescens Search Trop Picture |
Synonyms:
| matridin-15-one |