rubia tinctorum root
dried, crushed roots of the madder, rubia tinctorum l., rubiaceae
 
Notes:
None found
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Name: rubia tinctorum root
CAS Number: 84650-16-8 
ECHA EC Number: 283-497-9
Category: food additive and cosmetic agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
soothing agents
tonic
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Suppliers:
Aromaplant
Madder Roots
Bristol Botanicals
Madder root powder Rubia tinctorum
Bristol Botanicals
Madder root Rubia tinctoria
Pangaea Sciences
Madder
Pride International
Madder root
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: food additive and cosmetic agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Recommendation for rubia tinctorum root flavor usage levels up to:
 not for flavor use.
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Safety References:
Daily Med: search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 rubia tinctorum root
Chemidplus: 0084650168
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References:
 rubia tinctorum root
Pubchem (sid): 135294213
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Other Information:
FDA Listing of Food Additive Status: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 rubia tinctorum root
Search Trop  Picture
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Synonyms:
 dried, crushed roots of the madder, rubia tinctorum l., rubiaceae
 madder root
 rubia iberica root
 rubia tinctorum var. iberica root
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Articles:
PubMed: Purpurin triggers caspase-independent apoptosis in Candida dubliniensis biofilms.
PubMed: High throughput screening of natural products for anti-mitotic effects in MDA-MB-231 human breast carcinoma cells.
PubMed: The natural compound Alizarin as an osteotropic drug for the treatment of bone tumors.
PubMed: Novel antifungal activity of purpurin against Candida species in vitro.
PubMed: Chemical structure determination of DNA bases modified by active metabolites of lucidin-3-O-primeveroside.
PubMed: Cytohistological and phytochemical study of madder root extracts obtained by ultrasonic and classical extractions.
PubMed: Induction of kidney and liver cancers by the natural food additive madder color in a two-year rat carcinogenicity study.
PubMed: [Study on processing mechanism of Pinellia ternate].
PubMed: [Study on irritation of calcium oxalate crystal in raw Pinellia ternata].
PubMed: Identification and quantification of the constituents of madder root by gas chromatography and high-performance liquid chromatography.
PubMed: The mutagenic potential of madder root in dyeing processes in the textile industry.
PubMed: [Examination of the anthraquinone composition in root-stock and root samples of Rubia tinctorium L. plants of different origins].
PubMed: Staining human lymphocytes and onion root cell nuclei with madder root.
PubMed: Two validated HPLC methods for the quantification of alizarin and other anthraquinones in Rubia tinctorum cultivars.
PubMed: Chemical and enzymatic hydrolysis of anthraquinone glycosides from madder roots.
PubMed: Protection against Trp-P-2 DNA adduct formation in C57bl6 mice by purpurin is accompanied by induction of cytochrome P450.
PubMed: Preventive effects of anthraquinone food pigments on the DNA damage induced by carcinogens in Drosophila.
PubMed: Protection against Trp-P-2 mutagenicity by purpurin: mechanism of in vitro antimutagenesis.
PubMed: Protection against the bacterial mutagenicity of heterocyclic amines by purpurin, a natural anthraquinone pigment.
PubMed: Carcinogenicity and DNA adduct formation observed in ACI rats after long-term treatment with madder root, Rubia tinctorum L.
PubMed: The Composition of Metals Bound to Class III Metallothionein (Phytochelatin and Its Desglycyl Peptide) Induced by Various Metals in Root Cultures of Rubia tinctorum.
PubMed: Acute and subacute toxicity tests of madder root, natural colorant extracted from madder (Rubia tinctorum), in (C57BL/6 X C3H)F1 mice.
PubMed: Comparative studies of rubia cordifolia linn. And rubia tinctorum linn (rubiaceae)(*).
PubMed: Pharmacokinetic studies of alizarin in man.
PubMed: Identification of a mutagenic substance, in Rubia tinctorum L. (madder) root, as lucidin.
PubMed: [Effect of drugs used for the prevention of urinary calculi recurrence on the growth and metabolism of young experimental animals].
PubMed: [The antibiotic effect of the madder root (Rubia tinctorium)].
PubMed: [Madder root for small urinary calculi].
PubMed: [Madder root in the therapy of nephrolithiasis].
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