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Category: cosmetic ingredient for skin conditioning
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | cosmetic ingredient for skin conditioning |
| Recommendation for polygonum multiflorum extract usage levels up to: | | | not for fragrance use.
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| Recommendation for polygonum multiflorum extract flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | elixir of life extract | | | extract of the herb polygonum, polygonum multiflorum, polygonaceae | | | fallopia multiflora extract | | | fo-ti extract |
Articles:
| PubMed: | Emodin inhibits tonic tension through suppressing PKCδ-mediated inhibition of myosin phosphatase in isolated rat thoracic aorta. |
| PubMed: | 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside (THSG) attenuates human platelet aggregation, secretion and spreading in vitro. |
| PubMed: | Effect of Nrf2 activators on release of glutathione, cysteinylglycine and homocysteine by human U373 astroglial cells. |
| PubMed: | Neuroprotective effects of Polygonum multiflorum extract against glutamate-induced oxidative toxicity in HT22 hippocampal cells. |
| PubMed: | Promotion effect of constituents from the root of Polygonum multiflorum on hair growth. |
| PubMed: | [Toxic hepatitis induced by Polygonum multiflorum]. |
| PubMed: | Simultaneous determination of seven hydrophilic bioactive compounds in water extract of Polygonum multiflorum using pressurized liquid extraction and short-end injection micellar electrokinetic chromatography. |
| PubMed: | Icariin from Epimedium brevicornum Maxim promotes the biosynthesis of estrogen by aromatase (CYP19). |
| PubMed: | Hexane extract from Polygonum multiflorum attenuates glutamate-induced apoptosis in primary cultured cortical neurons. |
| PubMed: | Toxicity of raw and processed roots of Polygonum multiflorum. |
| PubMed: | Lipid regulation effects of Polygoni Multiflori Radix, its processed products and its major substances on steatosis human liver cell line L02. |
| PubMed: | In vitro screening on amyloid precursor protein modulation of plants used in Ayurvedic and traditional Chinese medicine for memory improvement. |
| PubMed: | Pharmacokinetic profile of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside in mice after oral administration of Polygonum multiflorum extract. |
| PubMed: | Anti-proliferative effect of an extract of the root of Polygonum multiflorum Thunb. on MCF-7 human breast cancer cells and the possible mechanisms. |
| PubMed: | Ginsenoside Rb1, Rg1 and three extracts of traditional Chinese medicine attenuate ultraviolet B-induced G1 growth arrest in HaCaT cells and dermal fibroblasts involve down-regulating the expression of p16, p21 and p53. |
| PubMed: | Pharmacokinetics and tissue distribution of 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside from traditional Chinese medicine Polygonum multiflorum following oral administration to rats. |
| PubMed: | Topical application of Polygonum multiflorum extract induces hair growth of resting hair follicles through upregulating Shh and β-catenin expression in C57BL/6 mice. |
| PubMed: | In vitro antioxidant activities of maillard reaction products produced in the steaming process of Polygonum multiflorum root. |
| PubMed: | Protection by tetrahydroxystilbene glucoside against neurotoxicity induced by MPP+: the involvement of PI3K/Akt pathway activation. |
| PubMed: | Tetrahydroxystilbene glucoside ameliorates diabetic nephropathy in rats: involvement of SIRT1 and TGF-β1 pathway. |
| PubMed: | 5alpha-reductase inhibitory components as antiandrogens from herbal medicine. |
| PubMed: | Evaluation of anti-oxidant capacity of root of Scutellaria baicalensis Georgi, in comparison with roots of Polygonum multiflorum Thunb and Panax ginseng CA Meyer. |
| PubMed: | [Effect of compound Polygonum multiflorum extract on Alzheimer's disease]. |
| PubMed: | [Effects of extract of Polygonum multiflorum on cell cycle arrest and apoptosis of human liver cell line L02]. |
| PubMed: | Anti-HIV activities of the compounds isolated from Polygonum cuspidatum and Polygonum multiflorum. |
| PubMed: | Farnesyl protein transferase inhibitory components of Polygonum multiflorum. |
| PubMed: | Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-kappaB pathways and inhibition of intracellular ROS/RNS generation. |
| PubMed: | A new stilbene glucoside gallate from the roots of Polygonum multiflorum. |
| PubMed: | Screening of Chinese medicinal plants for inhibition against clinical isolates of methicillin-resistant Staphylococcus aureus (MRSA). |
| PubMed: | Effects of four medicinal herbs on human vascular endothelial cells in culture. |
| PubMed: | Anthraquinones, Cdc25B phosphatase inhibitors, isolated from the roots of Polygonum multiflorum Thunb. |
| PubMed: | An extract of Polygonum multiflorum protects against free radical damage induced by ultraviolet B irradiation of the skin. |
| PubMed: | Preparative isolation and purification of chemical constituents from the root of Polygonum multiflorum by high-speed counter-current chromatography. |
| PubMed: | Protective effect of Polygonum multiflorum Thunb on amyloid beta-peptide 25-35 induced cognitive deficits in mice. |
| PubMed: | Neuroprotective effects of Polygonum multiflorum on nigrostriatal dopaminergic degeneration induced by paraquat and maneb in mice. |
| PubMed: | [Study on optimizing extraction process of root of Polygonum multiflorum]. |
| PubMed: | Beneficial effects of different Polygonum multiflorum Thunb. extracts on memory and hippocampus morphology. |
| PubMed: | Long-term administration of Polygonum multiflorum Thunb. reduces cerebral ischemia-induced infarct volume in gerbils. |
| PubMed: | Anti-inflammatory activity of Chinese medicinal vine plants. |
| PubMed: | In vivo antioxidant action of a lignan-enriched extract of Schisandra fruit and an anthraquinone-containing extract of Polygonum root in comparison with schisandrin B and emodin. |
| PubMed: | The radical scavenging effects of stilbene glucosides from Polygonum multiflorum. |
| PubMed: | Myocardial protection against ischaemia-reperfusion injury by a Polygonum multiflorum extract supplemented 'Dang-Gui decoction for enriching blood', a compound formulation, ex vivo. |
| PubMed: | Myocardial protective effect of an anthraquinone-containing extract of Polygonum multiflorum ex vivo. |
| PubMed: | [Effect of ethanolic extract from root tuber of Polygonum multiflorum Thunb. on liver and brain monoamine oxidase in senescence-accelerated mice in vivo]. |
| PubMed: | Novel Ca(2+)-ATPase inhibitors from the dried root tubers of Polygonum Multiflorum. |
| PubMed: | Moderate inhibition of mutagenicity and carcinogenicity of benzo[a]pyrene, 1,6-dinitropyrene and 3,9-dinitrofluoranthene by Chinese medicinal herbs. |
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