steareth-1
octadecyl polyoxyethylene ether
 
Notes:
None found
Synonyms   Articles   Notes   Search
CAS Number: 9005-00-9Picture of molecule3D/inchi
Other(deleted CASRN): 106707-02-2
ECHA ELINCS - REACH Pre-Reg: 500-017-8
Nikkaji Web: J110.984G
XlogP3: 8.40 (est)
Molecular Weight: 314.55314000
Formula: C20 H42 O2
NMR Predictor: Predict (works with chrome or firefox)
Category: emulsifiers, surfactants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
FDA Mainterm (IAUFC):9005-00-9 ; PEG STEARYL ETHER
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 413.00 to  414.00 °C. @ 760.00 mm Hg (est)
Flash Point: > 212.00 °F. TCC ( > 100.00 °C. )
logP (o/w): 7.966 (est)
Soluble in:
 water, 0.01014 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
Odor Strength: none
 
Odor Description:
at 100.00 %. 
bland
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: surfactants
surfactant - emulsifying
Synonyms   Articles   Notes   Search   Top
Suppliers:
 None found
Synonyms   Articles   Notes   Search   Top
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  25000 mg/kg
Yakkyoku. Pharmacy. Vol. 31, Pg. 471, 1980.

oral-rat LD50  2900 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 690, 1969.

oral-rat LD50  1900 mg/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 690, 1969.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: emulsifiers, surfactants
Recommendation for steareth-1 usage levels up to:
 not for fragrance use.
 
Recommendation for steareth-1 flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA Substance Registry Services (TSCA): 9005-00-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 75050
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 2
 2-octadecoxyethanol
Chemidplus: 0002136723
RTECS: WI6250000 for cas# 9005-00-9
Synonyms   Articles   Notes   Search   Top
References:
 2-octadecoxyethanol
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 9005-00-9
Pubchem (cid): 75050
Pubchem (sid): 135031380
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Indirect Additives used in Food Contact Substances:View
CHEMBL: View
KEGG (GenomeNet): D08975
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
2-octadecoxyethanol
 octadecyl polyoxyethylene ether
 polyoxyl stearyl ether
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Surfactant effect on the physicochemical characteristics of cationic solid lipid nanoparticles.
PubMed: A cost-effective method to prepare curcumin nanosuspensions with enhanced oral bioavailability.
PubMed: A simple derivation of the critical condition for the ultrasonic atomization of polymer solutions.
PubMed: Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery.
PubMed: The in vitro impact of toothpaste extracts on cell viability.
PubMed: Curcumin-loaded solid lipid nanoparticles with Brij78 and TPGS improved in vivo oral bioavailability and in situ intestinal absorption of curcumin.
PubMed: Thermosensitive liposomes for the delivery of gemcitabine and oxaliplatin to tumors.
PubMed: Key structure of brij for overcoming multidrug resistance in cancer.
PubMed: EliA facilitates the induction of lipase expression by stearyl alcohol in Ralstonia sp. NT80.
PubMed: Solubilisation capacity of Brij surfactants.
PubMed: A thermosensitive liposome prepared with a Cu²⁺ gradient demonstrates improved pharmacokinetics, drug delivery and antitumor efficacy.
PubMed: In vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain.
PubMed: Tailored microcrystal growth: a facile solution-phase synthesis of gold rings.
PubMed: Efficient tumor regression by a single and low dose treatment with a novel and enhanced formulation of thermosensitive liposomal doxorubicin.
PubMed: Tresyl-based conjugation of protein antigen to lipid nanoparticles increases antigen immunogenicity.
PubMed: Development of the loratadine gel for enhanced transdermal delivery.
PubMed: Templating multiple length scales by combining phase separation, self-assembly and photopatterning in porous films.
PubMed: Preparation and characterization of solid lipid nanoparticles containing silibinin.
PubMed: Cell-free production of G protein-coupled receptors for functional and structural studies.
PubMed: Preparation and characterization of nickel nanoparticles for binding to his-tag proteins and antigens.
PubMed: The metabolism of fatty alcohols in lipid nanoparticles by alcohol dehydrogenase.
PubMed: Highly enantioselective epoxidation of 2,4-diarylenones by using dimeric cinchona phase-transfer catalysts: enhancement of enantioselectivity by surfactants.
PubMed: Paclitaxel nanoparticles for the potential treatment of brain tumors.
PubMed: A collaborative evaluation of the cytotoxicity of two surfactants by using the human corneal epithelial cell line and the WST-1 test.
PubMed: Intranasal administration of plasmid DNA-coated nanoparticles results in enhanced immune responses.
PubMed: Scale-up of an oil/water cream containing 40% diethylene glycol monoethyl ether.
PubMed: Growth and survival of Helicobacter pylori in defined medium and susceptibility to Brij 78.
PubMed: Inhibitory effects of polyoxyethylene stearate, PANTA, and neutral pH on growth of Mycobacterium genavense in BACTEC primary cultures.
PubMed: Effect of Brij-78 on systemic delivery of insulin from an ocular device.
PubMed: Immobilization of functionalized alkyl-poly(ethylene oxide) surfactants on poly(ethylene) surfaces by means of an argon plasma treatment.
PubMed: Effects of the structures of polyoxyethylene alkyl ethers on uptake of butyl p-hydroxybenzoate by Escherichia coli and its antibacterial activity.
PubMed: Albumin can reverse the release of potassium from human erythrocytes treated with the non-ionic detergent, Brij 58.
PubMed: Feasibility of glucagon eyedrops for clinical use in hypoglycemia.
PubMed: Chronic systemic delivery of insulin through the ocular route.
PubMed: Enhancement of systemic delivery of met-enkephalin and leu-enkephalin eyedrops with permeation enhancers.
PubMed: Effects of permeation enhancers BL-9 and Brij-78 on absorption of four peptide eyedrops in rabbits.
PubMed: Glucagon administration to the rat via eye drops.
PubMed: Systemic absorption of oxytocin and vasopressin through eyes in rabbits.
PubMed: Effect of permeation enhancers on beta-endorphin systemic uptake after topical application to the eye.
PubMed: Adjustment of blood sugar levels with insulin and glucagon eyedrops in normal and diabetic rabbits.
PubMed: A nuclear magnetic resonance (nmr) investigation of the micellar structure of a long-chain non-ionic surfactant.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2021 Perflavory ™ Disclaimer Privacy Policy