| PubMed: | Metabolic profiling of Gynostemma pentaphyllum extract in rat serum, urine and faeces after oral administration. |
| PubMed: | Hypoglycemic effect of Gynostemma pentaphyllum saponins by enhancing the Nrf2 signaling pathway in STZ-inducing diabetic rats. |
| PubMed: | Determination by UPLC-MS of four dammarane-type saponins from heat-processed Gynostemma pentaphyllum. |
| PubMed: | Gypenoside attenuates hepatic ischemia/reperfusion injury in mice via anti-oxidative and anti-apoptotic bioactivities. |
| PubMed: | Protective effects of Gynostemma pentaphyllum polysaccharides on PC12 cells impaired by MPP(+). |
| PubMed: | Anticancer and immunoregulatory activity of Gynostemma pentaphyllum polysaccharides in H22 tumor-bearing mice. |
| PubMed: | Anti-cancer effect and the underlying mechanisms of gypenosides on human colorectal cancer SW-480 cells. |
| PubMed: | Effects of gypenosides on anxiety disorders in MPTP-lesioned mouse model of Parkinson's disease. |
| PubMed: | The Effect of Gynostemma pentaphyllum Extract on Mouse Dermal Fibroblasts. |
| PubMed: | Attenuation of Aβ25-35-induced parallel autophagic and apoptotic cell death by gypenoside XVII through the estrogen receptor-dependent activation of Nrf2/ARE pathways. |
| PubMed: | Characterization of a novel alkali-soluble heteropolysaccharide from tetraploid Gynostemma pentaphyllum Makino and its potential anti-inflammatory and antioxidant properties. |
| PubMed: | [Molecular diversity of arbuscular mycorrhizal fungi in wild and cultured Gynostemma pentaphyllum roots in Xishuangbanna, Southwest China]. |
| PubMed: | Cytotoxic activity of gypenosides and gynogenin against non-small cell lung carcinoma A549 cells. |
| PubMed: | Two novel anti-inflammatory 21-nordammarane saponins from tetraploid Jiaogulan ( Gynostemma pentaphyllum ). |
| PubMed: | Metabonomics study of the therapeutic mechanism of Gynostemma pentaphyllum and atorvastatin for hyperlipidemia in rats. |
| PubMed: | Arthrobacter gyeryongensis sp. nov., isolated from soil of a Gynostemma pentaphyllum field. |
| PubMed: | Two new saponins from tetraploid jiaogulan (Gynostemma pentaphyllum), and their anti-inflammatory and α-glucosidase inhibitory activities. |
| PubMed: | Herbal medicines for fatty liver diseases. |
| PubMed: | Antiproliferation and anti-migration induced by gypenosides in human colon cancer SW620 and esophageal cancer Eca-109 cells. |
| PubMed: | Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): a randomized, double-blind, placebo-controlled trial. |
| PubMed: | Toxicity evaluation of standardized extract of Gynostemma pentaphyllum Makino. |
| PubMed: | Characterization of a novel polysaccharide from tetraploid Gynostemma pentaphyllum makino. |
| PubMed: | Anxiolytic effects of herbal ethanol extract from Gynostemma pentaphyllum in mice after exposure to chronic stress. |
| PubMed: | Dammarane-type saponins from heat-processed Gynostemma pentaphyllum show fortified activity against A549 cells. |
| PubMed: | [Experimental research on prevention and treatment of fatty liver rats with Abrus cantoniensis]. |
| PubMed: | Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients. |
| PubMed: | Characterization of a heteropolysaccharide isolated from diploid Gynostemma pentaphyllum Makino. |
| PubMed: | Core-shell nanocarriers with ZnO quantum dots-conjugated Au nanoparticle for tumor-targeted drug delivery. |
| PubMed: | Ombuin-3-O-β-D-glucopyranoside from Gynostemma pentaphyllum is a dual agonistic ligand of peroxisome proliferator-activated receptors α and δ/β. |
| PubMed: | Chemical Composition of Three Polysaccharides From Gynostemma pentaphyllum and Their Antioxidant Activity in Skeletal Muscle of Exercised Mice. |
| PubMed: | Protein tyrosine phosphatase 1B inhibitory effect by dammarane-type triterpenes from hydrolyzate of total Gynostemma pentaphyllum saponins. |
| PubMed: | Chemical differentiation of two taste variants of Gynostemma pentaphyllum by using UPLC-Q-TOF-MS and HPLC-ELSD. |
| PubMed: | Antidiabetic Effects of Add-On Gynostemma pentaphyllum Extract Therapy with Sulfonylureas in Type 2 Diabetic Patients. |
| PubMed: | Reversal of P-gp and MRP1-mediated multidrug resistance by H6, a gypenoside aglycon from Gynostemma pentaphyllum, in vincristine-resistant human oral cancer (KB/VCR) cells. |
| PubMed: | Two new triterpene saponins from Gynostemma pentaphyllum. |
| PubMed: | Chemical composition of three polysaccharides from Gynostemma pentaphyllum and their antioxidant activity in skeletal muscle of exercised mice. |
| PubMed: | Protective effects of gypenosides against fatty liver disease induced by high fat and cholesterol diet and alcohol in rats. |
| PubMed: | Purification of a polysaccharide from Gynostemma pentaphyllum Makino and its therapeutic advantages for psoriasis. |
| PubMed: | Dammarane glycosides from the root of Machilus yaoshansis. |
| PubMed: | Isolation and antitumor activities of acidic polysaccharide from Gynostemma pentaphyllum Makino. |
| PubMed: | Restoration of electric footshock-induced immunosuppression in mice by Gynostemma pentaphyllum components. |
| PubMed: | Nuciferine stimulates insulin secretion from beta cells-an in vitro comparison with glibenclamide. |
| PubMed: | [Determination of arsenic, mercury and selenium in Gynostemma pentaphyllum and rhizospheric soil samples collected from different regions by hydride generation atomic fluorescence spectrometry]. |
| PubMed: | Heat-processed Gynostemma pentaphyllum extract improves obesity in ob/ob mice by activating AMP-activated protein kinase. |
| PubMed: | Preconditioning of brain slices against hypoxia induced injury by a Gynostemma pentaphyllum extract--stimulation of anti-oxidative enzyme expression. |
| PubMed: | Prevention of free fatty acid-induced lipid accumulation, oxidative stress, and cell death in primary hepatocyte cultures by a Gynostemma pentaphyllum extract. |
| PubMed: | Triterpenes possessing an unprecedented skeleton isolated from hydrolyzate of total saponins from Gynostemma pentaphyllum. |
| PubMed: | New dammarane-type glycosides from the roots of Gynostemma pentaphyllum. |
| PubMed: | [Study of xiaozhang recipe combined with lamivudine in treatment of 84 chronic viral hepatitis B patients with compensated liver cirrhosis]. |
| PubMed: | A new triterpenoid saponin from Gynostemma pentaphyllum. |
| PubMed: | New dammarane-type glucosides as potential activators of AMP-activated protein kinase (AMPK) from Gynostemma pentaphyllum. |
| PubMed: | Antiproliferation effect and apoptosis mechanism of prostate cancer cell PC-3 by flavonoids and saponins prepared from Gynostemma pentaphyllum. |
| PubMed: | Gypenosides improve cognitive impairment induced by chronic cerebral hypoperfusion in rats by suppressing oxidative stress and astrocytic activation. |
| PubMed: | Transcriptome profiling and insilico analysis of Gynostemma pentaphyllum using a next generation sequencer. |
| PubMed: | Antimicrobial activity of Gynostemma pentaphyllum extracts against fungi producing aflatoxin and fumonisin and bacteria causing diarrheal disease. |
| PubMed: | Gypenosides suppress growth of human oral cancer SAS cells in vitro and in a murine xenograft model: the role of apoptosis mediated by caspase-dependent and caspase-independent pathways. |
| PubMed: | Herbal extract of gynostemma pentaphyllum decreases hepatic glucose output in type 2 diabetic goto-kakizaki rats. |
| PubMed: | Microsatellite markers in the traditional Chinese medicinal herb Gynostemma pentaphyllum (Cucurbitaceae). |
| PubMed: | Dammarane-type saponins from Gynostemma pentaphyllum. |
| PubMed: | Chromatographic fingerprint analysis and rutin and quercetin compositions in the leaf and whole-plant samples of di- and tetraploid Gynostemma pentaphyllum. |
| PubMed: | Gypenoside TN-2 ameliorates scopolamine-induced learning deficit in mice. |
| PubMed: | Triterpenoid saponins from Gynostemma pentaphyllum. |
| PubMed: | Taxonomic significance of trichomes micromorphology in cucurbits. |
| PubMed: | Preparative chromatography of flavonoids and saponins in Gynostemma pentaphyllum and their antiproliferation effect on hepatoma cell. |
| PubMed: | Chinese herbal extracts (SK0506) as a potential candidate for the therapy of the metabolic syndrome. |
| PubMed: | Preparation of carotenoids and chlorophylls from Gynostemma pentaphyllum (Thunb.) Makino and their antiproliferation effect on hepatoma cell. |
| PubMed: | Chemical composition of five commercial Gynostemma pentaphyllum samples and their radical scavenging, antiproliferative, and anti-inflammatory properties. |
| PubMed: | An experimental study on the antileukemia effects of gypenosides in vitro and in vivo. |
| PubMed: | Gypenosides protects dopaminergic neurons in primary culture against MPP(+)-induced oxidative injury. |
| PubMed: | Long-term oral administration of Gynostemma pentaphyllum extract attenuates airway inflammation and Th2 cell activities in ovalbumin-sensitized mice. |
| PubMed: | Gypenosides causes DNA damage and inhibits expression of DNA repair genes of human oral cancer SAS cells. |
| PubMed: | Gypenosides inhibits migration and invasion of human oral cancer SAS cells through the inhibition of matrix metalloproteinase-2 -9 and urokinase-plasminogen by ERK1/2 and NF-kappa B signaling pathways. |
| PubMed: | Dammarane saponins from Gynostemma pentaphyllum. |
| PubMed: | Dammaranes from Gynostemma pentaphyllum and synthesis of their derivatives as inhibitors of protein tyrosine phosphatase 1B. |
| PubMed: | Neuroprotective effects of herbal ethanol extracts from Gynostemma pentaphyllum in the 6-hydroxydopamine-lesioned rat model of Parkinson's disease. |
| PubMed: | Dammarane-type saponins from Gynostemma pentaphyllum. |
| PubMed: | Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients. |
| PubMed: | Gynostemma pentaphyllum protects mouse male germ cells against apoptosis caused by zearalenone via Bax and Bcl-2 regulation. |
| PubMed: | Selective induction of apoptosis in glioma tumour cells by a Gynostemma pentaphyllum extract. |
| PubMed: | Dammarane-type glycosides from Gynostemma pentaphyllum and their effects on IL-4-induced eotaxin expression in human bronchial epithelial cells. |
| PubMed: | Gypenoside LXXIV ameliorates scopolamine-induced learning deficit in mice. |
| PubMed: | Gynostemosides A-E, megastigmane glycosides from Gynostemma pentaphyllum. |
| PubMed: | The inhibitory effect of Gynostemma pentaphyllum on MCP-1 and type I procollagen expression in rat hepatic stellate cells. |
| PubMed: | Screening of the hypoglycemic effect of eight Vietnamese herbal drugs. |
| PubMed: | [Fingerprints identification of Gynostemma pentaphyllum by RAPD and cloning and analysis of its specific DNA fragment]. |
| PubMed: | Effect of Gynostemma Pentaphyllum polysaccharide on boar spermatozoa quality following freezing-thawing. |
| PubMed: | Protection of hippocampal slices against hypoxia/hypoglycemia injury by a Gynostemma pentaphyllum extract. |
| PubMed: | Protein tyrosine phosphatase 1B inhibitory by dammaranes from Vietnamese Giao-Co-Lam tea. |
| PubMed: | Polyploid origins in Gynostemma pentaphyllum (Cucurbitaceae) inferred from multiple gene sequences. |
| PubMed: | Potential hypoglycemic effect of an ethanol extract of Gynostemma pentaphyllum in C57BL/KsJ-db/db mice. |
| PubMed: | Immunomodulatory effects of cadmium and Gynostemma pentaphyllum herbal tea on rat splenocyte proliferation. |
| PubMed: | Determination of flavonoids and saponins in Gynostemma pentaphyllum (Thunb.) Makino by liquid chromatography-mass spectrometry. |
| PubMed: | Gypenosides induced G0/G1 arrest via CHk2 and apoptosis through endoplasmic reticulum stress and mitochondria-dependent pathways in human tongue cancer SCC-4 cells. |
| PubMed: | Isolation and characterization of immunostimulatory polysaccharide from an herb tea, Gynostemma pentaphyllum Makino. |
| PubMed: | Determination of chlorophylls and their derivatives in Gynostemma pentaphyllum Makino by liquid chromatography-mass spectrometry. |
| PubMed: | Gynostemma pentaphyllum decreases allergic reactions in a murine asthmatic model. |
| PubMed: | Gypenosides inhibited invasion and migration of human tongue cancer SCC4 cells through down-regulation of NFkappaB and matrix metalloproteinase-9. |
| PubMed: | Gypenosides induced G0/G1 arrest via inhibition of cyclin E and induction of apoptosis via activation of caspases-3 and -9 in human lung cancer A-549 cells. |
| PubMed: | [The effect of Gynostemma pentaphyllum (GP) on plasma lipoprotein metabolism and lipoperoxidation lipoprotein in the experimental hyperglycemia rats]. |
| PubMed: | The molecular mechanism of gypenosides-induced G1 growth arrest of rat hepatic stellate cells. |
| PubMed: | Method development for gypenosides fingerprint by high performance liquid chromatography with diode-array detection and the addition of internal standard. |
| PubMed: | [Influence of FPS on the expression of LDL-R mRNA in the liver tissues of hyperlipidemic rats]. |
| PubMed: | [Studies on the HPLC fingerprint spectrum of flavonoids in Gynostemma pentaphyllum]. |
| PubMed: | Specific reversal of multidrug resistance to colchicine in CEM/VLB(100) cells by Gynostemma pentaphyllum extract. |
| PubMed: | Determination of the three-dimensional structure of Gynoside A in solution using NMR and molecular modeling. |
| PubMed: | Gypenosides inhibited N-acetylation of 2-aminofluorene, N-acetyltransferase gene expression and DNA adduct formation in human cervix epithelioid carcinoma cells (HeLa). |
| PubMed: | Extract of Gynostemma pentaphyllum enhanced the production of antibodies and cytokines in mice. |
| PubMed: | Gypenoside XLIX, a naturally occurring PPAR-alpha activator, inhibits cytokine-induced vascular cell adhesion molecule-1 expression and activity in human endothelial cells. |
| PubMed: | Phytopreventative effects of Gynostemma pentaphyllum against acute Indomethacin-induced gastrointestinal and renal toxicity in rats. |
| PubMed: | The possible mechanisms by which phanoside stimulates insulin secretion from rat islets. |
| PubMed: | Anti-hyperlipidemic and hypoglycemic effects of Gynostemma pentaphyllum in the Zucker fatty rat. |
| PubMed: | Gypenosides induced apoptosis in human colon cancer cells through the mitochondria-dependent pathways and activation of caspase-3. |
| PubMed: | Nine new dammarane saponins from Gynostemma pentaphyllum. |
| PubMed: | Gypenoside XLIX, a naturally occurring gynosaponin, PPAR-alpha dependently inhibits LPS-induced tissue factor expression and activity in human THP-1 monocytic cells. |
| PubMed: | [Simultaneous determination of total flavone and total saponin in Gynostemma pentaphyllum by signal multiplier spectrophotometry]. |
| PubMed: | [The extraction, purification and assaying of Gynostemma pentaphyllum polysaccharides]. |
| PubMed: | Determination of trace elements in herbal tea products and their infusions consumed in Thailand. |
| PubMed: | Management of SAH with traditional Chinese medicine in China. |
| PubMed: | The add-on effects of Gynostemma pentaphyllum on nonalcoholic fatty liver disease. |
| PubMed: | Gypenoside XLIX isolated from Gynostemma pentaphyllum inhibits nuclear factor-kappaB activation via a PPAR-alpha-dependent pathway. |
| PubMed: | Phytopreventative anti-hyperlipidemic effects of gynostemma pentaphyllum in rats. |
| PubMed: | Haemolytic activities and adjuvant effect of Gynostemma pentaphyllum saponins on the immune responses to ovalbumin in mice. |
| PubMed: | Three dammarane-type saponins from Gynostemma pentaphyllum. |
| PubMed: | Cardiovascular effects of the aqueous extract of Gynostemma pentaphyllum Makino. |
| PubMed: | Antimutagenicity and DT-diaphorase inducing activity of Gynostemma pentaphyllum Makino extract. |
| PubMed: | Hairy root cultures of Gynostemma pentaphyllum (Thunb.) Makino: a promising approach for the production of gypenosides as an alternative of ginseng saponins. |
| PubMed: | A novel LXR-alpha activator identified from the natural product Gynostemma pentaphyllum. |
| PubMed: | Bronchodilatory effects of the aqueous extract of Gynostemma pentaphyllum and gypenosides III and VIII in anaesthetized guinea-pigs. |
| PubMed: | [Histochemical localization of ginsenosides in Gynostemma pentaphyllum and the content changes of total gypenosides]. |
| PubMed: | [Study on spectral properties of Chinese herbal medicines additives in cosmetic]. |
| PubMed: | [The analysis of Gynostemma pentaphyllum (Thunb) Makino for Chinese crude drug by FTIR and FT-Raman]. |
| PubMed: | [Photosynthetic characteristics of Gynostemma pentaphyllum under shade]. |
| PubMed: | [Composition analysis and dominance test of three kinds of raw variety of Gynostemma pentaphyllum]. |
| PubMed: | Novel dammarane-type glycosides from Gynostemma pentaphyllum. |
| PubMed: | [Studies on sex identification and variation of endogenous hormones in female and male plants of Gynostemma pentaphyllum]. |
| PubMed: | Chronic toxicity of Gynostemma pentaphyllum. |
| PubMed: | [Effect of Chinese herbal medicine 1023 Recipe in blocking cancer transformation of experimental precancerous lesion and its mechanism]. |
| PubMed: | The anti-gastric ulcer effect of Gynostemma pentaphyllum Makino. |
| PubMed: | Five new Ocotillone-type saponins from Gynostemma pentaphyllum. |
| PubMed: | A novel insulin-releasing substance, phanoside, from the plant Gynostemma pentaphyllum. |
| PubMed: | Dammarane-type glycosides from Gynostemma pentaphyllum. |
| PubMed: | [Determination of six nutritional elements in Chinese herbal medicines by graphite furnace atomic absorption spectrometry]. |
| PubMed: | [Light environment characteristics of forest gap in deciduous broad-leaved forest and its effects on growth features of Gynostemma pentaphyllum in Jianghuai watershed]. |
| PubMed: | Gypenosides derived from Gynostemma pentaphyllum suppress NO synthesis in murine macrophages by inhibiting iNOS enzymatic activity and attenuating NF-kappaB-mediated iNOS protein expression. |
| PubMed: | [Comparison of total saponin content in three wild species of Gynostemma on Mount Emei]. |
| PubMed: | [Scavenging effects of Astragalus and Gynostemma pentaphyllum with its product on O2-. and .OH]. |
| PubMed: | Regulation of Bcl-2 family molecules and activation of caspase cascade involved in gypenosides-induced apoptosis in human hepatoma cells. |
| PubMed: | [Dynamic features of some biochemical constituents in Gynostemma pentaphyllum under different environments]. |
| PubMed: | Inhibitory effects of gynostemma pentaphyllum on the UV induction of bacteriophage lambda in lysogenic Escherichia coli. |
| PubMed: | Effect of gynostemma pentaphyllum mak on carcinomatous conversions of golden hamster cheek pouches induced by dimethylbenzanthracene: a histological study. |
| PubMed: | Therapeutic effect of gypenoside on chronic liver injury and fibrosis induced by CCl4 in rats. |
| PubMed: | Antioxidant and hepatoprotective effects of Anoectochilus formosanus and Gynostemma pentaphyllum. |
| PubMed: | Gypenoside induces apoptosis in human Hep3B and HA22T tumour cells. |
| PubMed: | The direct release of nitric oxide by gypenosides derived from the herb Gynostemma pentaphyllum. |
| PubMed: | Gynostemma pentaphyllum: identification of major sapogenins and differentiation from Panax species. |
| PubMed: | [Determination on the glycosyl sequence of gypenoside A by TLC-FABMS]. |
| PubMed: | [The study of influencing cellular dynamics of gynostemma pentaphyllum on golden hamster cheek pouch premalignancy] |
| PubMed: | New triterpenoid saponins from Gynostemma pentaphyllum. |
| PubMed: | [The effect of Gynostemma pentaphyllum mak (GP) on carcinogenesis of the golden hamster cheek pouch induced by DMBA]. |
| PubMed: | [Observation of the effectiveness of compound Gynostemma Pentaphyllum Mak in golden hamster cheek pouch's premalignancy] |
| PubMed: | Protective effects of Gynostemma pentaphyllum in gamma-irradiated mice. |
| PubMed: | [A preliminary observation of preventive and blocking effect of Gynostemma pentaphyllum (Thunb) Makino on esophageal cancer in rats]. |
| PubMed: | New dammarane-type glycosides from Gynostemma pentaphyllum. |
| PubMed: | [Effects of 24 Chinese medicinal herbs on nucleic acid, protein and cell cycle of human lung adenocarcinoma cell]. |
| PubMed: | Protoplast culture and plant regeneration from the suspension cells of Gynostemma pentaphyllum (Thumb) Mak. |
| PubMed: | [Systematic concept and development model for the production base of Gynostemma pentaphyllum (Thunb.) Madino]. |
| PubMed: | [Agronomic standardization of Gynostemma pentaphyllum (Thunb.) Makino]. |
| PubMed: | [Intercropping techniques for Gynostemma pentaphyllum (Thunb.) Makino]. |
| PubMed: | [Semi-culture techniques for Gynostemma pentaphyllum (Thunb.) Makino]. |
| PubMed: | [Antithrombotic effect of Gynostemma pentaphyllum]. |
| PubMed: | Evaluation of the anti-inflammatory and liver-protective effects of anoectochilus formosanus, ganoderma lucidum and gynostemma pentaphyllum in rats. |
| PubMed: | Protective effect of gypenosides against oxidative stress in phagocytes, vascular endothelial cells and liver microsomes. |
| PubMed: | [Introduction and cultivation of Gynostemma pentaphyllum Mark. in Beijing]. |
| PubMed: | Effects of gynostemma pentaphyllum makino on the immunological function of cancer patients. |
| PubMed: | [Spectrophotometric determination of micro-amounts of zinc in Gynostemma pentaphyllum (Thunb.) Makino]. |
| PubMed: | [Isolation and identification of flavonoids and organic acids from Gynostemma pentaphyllum Makino]. |
| PubMed: | [Clonal propagation of Gynostemma pentaphyllum (Thumb.) Makino in test tubes]. |
| PubMed: | [A comparative identification of four Gynostemma spp. herbs and their various species from Guangxi]. |
| PubMed: | [Rapid propagation of Gynostemma pentaphyllum Makino via tissue culture]. |
| PubMed: | A new platelet aggregation factor from Gynostemma pentaphyllum Makino. |