Articles:
L-epigallocatechin gallate
Notes:
antimutagen in green tea (camellia sinensis); a steroid 5alpha-reductase inhibitor. Present in black tea and green tea (Thea sinensis)
Epigallocatechin gallate (EGCG) is the principal catechin in tea from Camellia sinensis, the most consumed beverage worldwide (after water). Depending on brew time and temperature, a single cup of green tea may contain 100-200 mg EGCG.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 989-51-5 Epigallocatechin Gallate EGCG, also called Epigallocatechin gallate, under the IUPAC name [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate,
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GP0260 Epigallocatechin gallate
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O'Laughlin Industries Inc. Manufacturer of chemicals and ingredients used in flavors, fragrances, food, beverages and cosmetics Leading the Flavor and Fragrance Industry since 1980. O'Laughlin was established in 1980 by its owner and chief executive Michael O'Laughlin, when he moved to Beijing, China and established a small office. Since then it has grown to be a world class producer of chemicals, with significant production facilities in China, and distribution and sales in all major world markets. Email: Sales US Email: John Gick Voice: (852) 2527-1031 Fax: (852) 2529-0231 US Voice: (973) 376-4600 US Fax: (973) 376-4630 Product(s): 774-7142 EGCG Natural 90
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| CAS Number: | 989-51-5 |  3D/inchi
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| Other(deleted CASRN): | 863-65-0 | |
| FDA UNII: | BQM438CTEL | |
| Nikkaji Web: | J134.058A | |
| Beilstein Number: | 3658838 | |
| MDL: | MFCD00075940 | |
| XlogP3: | 1.20 (est) | |
| Molecular Weight: | 458.37666000 | |
| Formula: | C22 H18 O11 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: antioxidants
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 222.00 to 224.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 909.00 to 910.00 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 608.00 °F. TCC ( 320.00 °C. ) (est) |
| logP (o/w): | 0.639 (est) |
| Soluble in: | |
| water, 32.77 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
antioxidants |
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Epigallocatechin gallate 98% |
| BOC Sciences |
| For experimental / research use only. |
| Epigallocatechin Gallate
Odor: characteristic Use: EGCG, also called Epigallocatechin gallate, under the IUPAC name [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate, |
| EMD Millipore |
| For experimental / research use only. |
| (–)-epiGallocatechin Gallate |
| ExtraSynthese |
| For experimental / research use only. |
| (-)-Epigallocatechin gallate (HPLC) ≥98% |
| Givaudan |
| Inoveol® EGCG
Odor: characteristic Use: Green tea benefits from a long term botanical tradition in Asia due to its fantastic preventive and protective effects on health. EGCG (EpigalloCatechin Gallate) is one of green tea most active molecule. Inoveol® EGCG is a
new cosmetic dedicated form of EGCG: highly water soluble, stabilised and purified, this « molecular sponge » captures free radicals, detoxifies and prevents ageing. |
| Glentham Life Sciences |
| Epigallocatechin gallate |
| Nacalai USA |
| For experimental / research use only. |
| (-)-epiGallocatechin Gallate |
| O'Laughlin Industries |
| EGCG Natural 90 |
| Sigma-Aldrich |
| For experimental / research use only. |
| (-)-Epigallocatechin Gallate
analytical standard |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
oral-mouse LD50 2170 mg/kg Kiso to Rinsho. Clinical Report. Vol. 21, Pg. 4601, 1987. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | antioxidants | ||
| Recommendation for epigallocatechin gallate usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for epigallocatechin gallate flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| European Food Safety Authority (EFSA) reference(s): | |
| Scientific opinion on the safety of green tea catechins View page or View pdf | |
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 65064 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 2 |
| [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate | |
| Chemidplus: | 0000989515 |
| RTECS: | KB5200000 for cas# 989-51-5 |
References:
| [(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 65064 |
| Pubchem (sid): | 135021682 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C09731 |
| HMDB (The Human Metabolome Database): | HMDB03153 |
| FooDB: | FDB017702 |
| MedlinePlusSupp: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| grape Search Trop Picture | |
| pomegranate fruit juice Search Trop Picture | |
| pomegranate leaf Search Trop Picture | |
| star fruit Search Trop Picture | |
| tea black tea Search Trop Picture | |
| tea green tea Search Trop Picture | |
| tea leaf Search Trop Picture | |
| tea shoot Search Trop Picture |
Synonyms:
| benzoic acid, 3,4,5-trihydroxy-, (2R,3R)-3,4-dihydro-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-2H-1-benzopyran-3-yl ester | |
| (2R,3R)-5,7- | dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate |
| [(2R,3R)-5,7- | dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate |
| (2R,3R)-5,7- | dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl 3,4,5-trihydroxybenzoate |
| [(2R,3R)-5,7- | dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate |
| EGCG | |
| (-)-epi | gallocatechin 3-gallate |
| epi | gallocatechin 3-gallate |
| (-)-epi | gallocatechin 3-O-gallate |
| (-)-epi | gallocatechin gallate |
| L-epi | gallocatechin gallate |
| epi | gallocatechin-3-monogallate |
| (-)-epi | gallocatechin-3-o-gallate |
| (-)-epi | gallocatechol gallate |
| tea catechin | |
| teavigo |