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Category: cosmetic ingredient for skin protecting
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 117.50 °C. @ 760.00 mm Hg
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| Boiling Point: | 270.20 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 254.00 °F. TCC ( 123.50 °C. ) (est)
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| logP (o/w): | 1.400 (est) |
| Soluble in: |
| | water, 7000 mg/L @ 25 °C (exp) | | | water, 1.226e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | cosmetic ingredient for skin protecting |
| Recommendation for hordenine usage levels up to: | | | not for fragrance use.
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| Recommendation for hordenine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| N,N- | dimethyl-p-hydroxyphenethylamine | | 4-[2-( | dimethylamino)ethyl]phenol | | 4-(2- | dimethylaminoethyl)phenol | | p-(2- | dimethylaminoethyl)phenol | | | eremursine |
Articles:
| PubMed: | The total alkaloids of Aconitum tanguticum protect against lipopolysaccharide-induced acute lung injury in rats. |
| PubMed: | At a supra-physiological concentration, human sexual hormones act as quorum-sensing inhibitors. |
| PubMed: | ["Legal highs" from the German internet--"bath salt drugs" on the rise]. |
| PubMed: | Hordenine, a single compound produced during barley germination, inhibits melanogenesis in human melanocytes. |
| PubMed: | High-performance liquid chromatographic analysis of biogenic amines in pharmaceutical products containing Citrus aurantium. |
| PubMed: | Analysis of anonymous pooled urine from portable urinals in central London confirms the significant use of novel psychoactive substances. |
| PubMed: | Sports drug testing: Analytical aspects of selected cases of suspected, purported, and proven urine manipulation. |
| PubMed: | Alkaloid diversity in Galanthus elwesii and Galanthus nivalis. |
| PubMed: | [Alkaloids from Senecio scandens]. |
| PubMed: | Changes in apolar metabolites during in vitro organogenesis of Pancratium maritimum. |
| PubMed: | Antimicrobial evaluation of clerodane diterpenes from Polyalthia longifolia var. pendula. |
| PubMed: | Certification of standard reference materials containing bitter orange. |
| PubMed: | Mass spectrometric determination of the predominant adrenergic protoalkaloids in bitter orange (Citrus aurantium). |
| PubMed: | Revised NMR data for incartine: an alkaloid from Galanthus elwesii. |
| PubMed: | Fast high-performance liquid chromatography analysis of phenethylamine alkaloids in Citrus natural products on a pentafluorophenylpropyl stationary phase. |
| PubMed: | Chromatographic and electrophoretic methods for the analysis of phenethylamine [corrected] alkaloids in Citrus aurantium. |
| PubMed: | Determination of bitter orange alkaloids in dietary supplement Standard Reference Materials by liquid chromatography with atmospheric-pressure ionization mass spectrometry. |
| PubMed: | Determination of synephrine in weight-loss products using high performance liquid chromatography with acidic potassium permanganate chemiluminescence detection. |
| PubMed: | Determination of synephrine in bitter orange raw materials, extracts, and dietary supplements by liquid chromatography with ultraviolet detection: single-laboratory validation. |
| PubMed: | Efficient and sensitive method for quantitative analysis of alkaloids in hardinggrass (Phalaris aquatica L.). |
| PubMed: | Phenylalkylamine alkaloids from Stapelia hirsuta L. |
| PubMed: | Alkaloids of Haloxylon salicornicum (Moq.) Bunge ex Boiss. (Chenopodiaceae). |
| PubMed: | Galanthindole: a new indole alkaloid from Galanthus plicatus ssp. byzantinus. |
| PubMed: | Characterization of cereal toxicity for celiac disease patients based on protein homology in grains. |
| PubMed: | Development of immunoassays for tyramine and tryptamine toxins of Phalaris aquatica L. |
| PubMed: | Hydroxylating activity of tyrosinase and its dependence on hydrogen peroxide. |
| PubMed: | [Pharmacological effects of hordenine]. |
| PubMed: | Influence of organic cations on basic amino-acid uptake by human placental villi. |
| PubMed: | Biologically active secondary metabolites of barley. IV. Hordenine production by different barley lines. |
| PubMed: | Biologically active secondary metabolites of barley. III. A method for identification and quantification of hordenine and gramine in barley by high-performance liquid chromatography. |
| PubMed: | Biologically active secondary metabolites of barley. II. Phytotoxicity of barley allelochemicals. |
| PubMed: | Technical note: an improved method for extraction and quantification of toxic phenethylamines from Acacia berlandieri. |
| PubMed: | Screening and confirmation of drugs in urine: interference of hordenine with the immunoassays and thin layer chromatography methods. |
| PubMed: | Kaempferol-3-O-glucosyl(1-2)rhamnoside from Ginkgo biloba and a reappraisal of other gluco(1-2, 1-3 and 1-4)rhamnoside structures. |
| PubMed: | Hordenine: pharmacology, pharmacokinetics and behavioural effects in the horse. |
| PubMed: | Deamination of hordenine by monoamine oxidase and its action on vasa deferentia of the rat. |
| PubMed: | Experimental evidence that tryptamine alkaloids do not cause Phalaris aquatica sudden death syndrome in sheep. |
| PubMed: | Rapid formation of N-nitrosodimethylamine from gramine, a naturally occurring precursor in barley malt. |
| PubMed: | Separation of two distinct S-adenosylmethionine dependent N-methyltransferases involved in hordenine biosynthesis in Hordeum vulgare. |
| PubMed: | N-nitrosodimethylamine in malt beverages--anticipatory action by the brewing industry. |
| PubMed: | N-nitrosodimethylamine precursors in malt. |
| PubMed: | Candicine from Stapelia gigantea. |
| PubMed: | Some hematological and histopathological effects of the alkaloids gramine and hordenine on meadow voles (Microtus pennsylvanicus). |
| PubMed: | [Scope and limitations of the analytical use of dansyl chloride, I: The reaction of aromatic sulfonyl chlorides with aliphatic tertiary amines: the microanalytical aspects of the Hinsberg test (author's transl)]. |
| PubMed: | Cactus alkaloids. XXXIV. Hordenine HCL from Coryphantha vivipara var. arizonica. |
| PubMed: | Cactus alkaloids. XXXI. beta-Phenethylamines and tetrahydroisoquinolines from the Mexican cactus dolichothele uberiformis. |
| PubMed: | Hordenine for Polyporous berkeleyi. |
| PubMed: | The action of hordenine on the superior cervical ganglion of the cat. |
| PubMed: | yote Alkaloids: Identification in the Mexican ictus Pelecyphora aselliformis Ehrenberg. |
| PubMed: | [Power of posthypophyseal preparations partially to reestablish the hypertensive action of hordenine first suppressed by adrenolytics]. |
| PubMed: | Cactus alkaloids. X. Isolation of hordenine and N-methyltyramine from Ariocarpus kotschoubeyanus. |
| PubMed: | Identity of peyocactin, an antibiotic from peyote (Lophophora williamsii), and hordenine. |
| PubMed: | The distribution of tyramine, N-methyltyramine, hordenine, octopamine, and synephrine in higher plants. |
| PubMed: | Cactus alkaloids. VI. Identification of hordenine and N--methyltyramine in Ariocarpus fissuratus varieties fissuratus and lloydii. |
| PubMed: | Cactus alkaloids. V. Isolation of hordenine and N-methyltyramine from Ariocarpus retusus. |
| PubMed: | Action of various sympathomimetic amines on the isolated stripped vas deferens of the guinea-pig. |
| PubMed: | Presence of hordenine in Lophophora williamsii. |
| PubMed: | THE ISOLATION OF HORDENINE AND NORSECURININE FROM SECURINEGA VIROSA (BAILL.). THE STRUCTURE OF NORSECURININE. |
| PubMed: | Effects of hordenine sulfate and methiodide on the receptors for the sweating axon reflex and on the sweat glands in the human skin. |
| PubMed: | Biosynthesis of Hordenine in Tissue Homogenates of Panicum miliaceum L. |
| PubMed: | The accumulation of hordenine in the seedings of Panicum miliaceum. |
| PubMed: | [Effect of hypocapnic anoxemia on hordenine induced vasoconstriction]. |
| PubMed: | [Not available]. |
| PubMed: | Action of hordenine compounds on the central nervous system. |
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