3-hydroxy-4-pentene nitrile, 27451-36-1

Articles:

PubMed:	Could nitrile derivatives of turnip (Brassica rapa) glucosinolates be hepato- or Cholangiotoxic in cattle?
PubMed:	Biomarkers of exocrine pancreatic injury in 2 rat acute pancreatitis models.
PubMed:	Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1-cyano-2-hydroxy-3-butene in the rat.
PubMed:	Induction of apoptosis by crambene protects mice against acute pancreatitis via anti-inflammatory pathways.
PubMed:	Identification of novel peptide safety markers for exocrine pancreatic toxicity induced by cyanohydroxybutene.
PubMed:	Evaluation of two novel peptide safety markers for exocrine pancreatic toxicity.
PubMed:	Crambene induces pancreatic acinar cell apoptosis via the activation of mitochondrial pathway.
PubMed:	Synergy among phytochemicals within crucifers: does it translate into chemoprotection?
PubMed:	Crambene, a bioactive nitrile derived from glucosinolate hydrolysis, acts via the antioxidant response element to upregulate quinone reductase alone or synergistically with indole-3-carbinol.
PubMed:	The cruciferous nitrile crambene has bioactivity similar to sulforaphane when administered to Fischer 344 rats but is far less potent in cell culture.
PubMed:	Rapid isolation and purification of 1-cyano-2-hydroxy-3-butene (crambene) from Crambe abyssinica seed meal using immiscible solvent extraction and high-performance liquid chromatography.
PubMed:	The synergistic upregulation of phase II detoxification enzymes by glucosinolate breakdown products in cruciferous vegetables.
PubMed:	Preparation and biological activity of four epiprogoitrin myrosinase-derived products.
PubMed:	Induction of rat pancreatic glutathione S-transferase and quinone reductase activities by a mixture of glucosinolate breakdown derivatives found in Brussels sprouts.
PubMed:	Induction of apoptosis in pancreatic acinar cells reduces the severity of acute pancreatitis.
PubMed:	The cruciferous nitrile, crambene, induces rat hepatic and pancreatic glutathione S-transferases.
PubMed:	A comparison of the individual and collective effects of four glucosinolate breakdown products from brussels sprouts on induction of detoxification enzymes.
PubMed:	Studies on the toxic effects of crambe meal and two of its constituents, 1-cyano-2-hydroxy-3-butene (CHB) and epi-progoitrin, in broiler chick diets.
PubMed:	Differential effect of cyanohydroxybutene on glutathione synthesis in liver and pancreas of male rats.
PubMed:	Differential effects of cyanohydroxybutene and selenium on normal and neoplastic canine mammary cells in vitro.
PubMed:	In vitro metabolism of cyanohydroxybutene: formation of a glutathione-S-transferase catalyzed product.
PubMed:	Separation of the toxic and glutathione-enhancing effects of the naturally occurring nitrile, cyanohydroxybutene.
PubMed:	The acute pancreatotoxic effects of the plant nitrile 1-cyano-2-hydroxy-3-butene.
PubMed:	Enhancement of pancreatic and hepatic glutathione levels in rats during cyanohydroxybutene intoxication.
PubMed:	The relationship of vehicle to target organ toxicology induced by the naturally occurring nitrile 1-cyano-2-hydroxy-3-butene.
PubMed:	Selective pancreato-toxicity in the rat induced by the naturally occurring plant nitrile 1-cyano-2-hydroxy-3-butene.
PubMed:	Studies on the effects of rapeseed meal on thyroid status of cattle, glucosinolate and iodine content of milk and other parameters.
PubMed:	(S)- and (R)-1-cyano-2-hydroxy-3-butene from myrosinase hydrolysis of epi-progoitrin and progoitrin.