serotonin
hippophain
 
Notes:
Isol. from bananas and other fruits. Also from cotton (Gossypium hirsutum) [DFC]
  • BOC Sciences
    • BOC Sciences
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      Product(s):
      50-67-9 5-Hydroxytryptamine >98%
       
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CAS Number: 50-67-9Picture of molecule3D/inchi
FDA UNII: 333DO1RDJY
Nikkaji Web: J4.107F
Beilstein Number: 0143524
MDL: MFCD00055054
XlogP3: 0.20 (est)
Molecular Weight: 176.21884000
Formula: C10 H12 N2 O
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 water, 2.00E+04 mg/L @ 27C (exp)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
BOC Sciences
For experimental / research use only.
5-Hydroxytryptamine >98%
Sigma-Aldrich
For experimental / research use only.
Serotonin analytical standard
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-cat LDLo  5 mg/kg
CARDIAC: OTHER CHANGES LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Farmakologiya i Toksikologiya Vol. 26, Pg. 10, 1963.

intravenous-guinea pig LD50  12800 ug/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 168, Pg. 373, 1967.

intramuscular-mouse LD50  750 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 112, Pg. 319, 1957.

intraperitoneal-mouse LD50  160 mg/kg
Indian Journal of Physiology and Pharmacology. Vol. 17, Pg. 31, 1973.

intravenous-mouse LD50  81 mg/kg
BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Farmakologiya i Toksikologiya Vol. 26, Pg. 10, 1963.

oral-mouse LD50  60 mg/kg
Meditsinskii Zhurnal Uzbekistana. Vol. (3), Pg. 61, 1985.

unreported-mouse LD50  250 mg/kg
"CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 8(1), Pg. 122, 1982.

intravenous-rat LD50  30 mg/kg
Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.

Dermal Toxicity:
subcutaneous-mouse LD50 601 mg/kg
BEHAVIORAL: ATAXIA BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Farmakologiya i Toksikologiya Vol. 26, Pg. 10, 1963.

subcutaneous-rat LD50 285 mg/kg
Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for serotonin usage levels up to:
 not for fragrance use.
 
Recommendation for serotonin flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
ClinicalTrials.gov: search
Daily Med: search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 5202
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 3
 3-(2-aminoethyl)-1H-indol-5-ol
Chemidplus: 0000050679
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References:
 3-(2-aminoethyl)-1H-indol-5-ol
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 5202
Pubchem (cas): 50-67-9
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
Golm Metabolome Database: Search
Metabolomics Database: Search
KEGG (GenomeNet): C00780
HMDB (The Human Metabolome Database): HMDB00259
FooDB: FDB012158
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 avocado fruit
Search Trop  Picture
 banana fruit
Search Trop  Picture
 banana hull husk
Search Trop  Picture
 banana plant
Search Trop  Picture
 bean scarlet runner bean
Search Trop  Picture
 buckthorn sea buckthorn
Search Trop  Picture
 buckthorn sea buckthorn bark
Search Trop  Picture
 cacao bean
Search Trop  Picture
 cacao plant
Search Trop  Picture
 corn plant
Search Trop  Picture
 cotton fruit
Search Trop  Picture
 cotton mexican cotton
Search Trop  Picture
 date palm fruit
Search Trop  Picture
 eggplant fruit
Search Trop  Picture
 melon bitter melon fruit
Search Trop  Picture
 papaya plant
Search Trop  Picture
 pea leaf
Search Trop  Picture
 pineapple
Search Trop  Picture
 pineapple fruit
Search Trop  Picture
 pineapple plant
Search Trop  Picture
 plum fruit
Search Trop  Picture
 pomegranate fruit juice
Search Trop  Picture
 pomegranate seed
Search Trop  Picture
 potato fruit
Search Trop  Picture
 potato leaf
Search Trop  Picture
 tomato fruit
Search Trop  Picture
 walnut black walnut embryo
Search Trop  Picture
 walnut black walnut nut
Search Trop  Picture
 walnut english walnut embryo
Search Trop  Picture
 walnut english walnut nut
Search Trop  Picture
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Synonyms:
3-(2-aminoethyl)-1H-indol-5-ol
3-(beta-aminoethyl)-5-hydroxyindole
3-(2-aminoethyl)indol-5-ol
 antemovis
 hippophain
 indol-5-ol, 3-(2-aminoethyl)-
 substance DS
 thrombocytin
 thrombotonin
 tryptamine, 5-hydroxy-
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