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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 2.00E+04 mg/L @ 27C (exp) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intravenous-cat LDLo 5 mg/kg CARDIAC: OTHER CHANGES
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION Farmakologiya i Toksikologiya Vol. 26, Pg. 10, 1963.
intravenous-guinea pig LD50 12800 ug/kg Archives Internationales de Pharmacodynamie et de Therapie. Vol. 168, Pg. 373, 1967.
intramuscular-mouse LD50 750 mg/kg Archives Internationales de Pharmacodynamie et de Therapie. Vol. 112, Pg. 319, 1957.
intraperitoneal-mouse LD50 160 mg/kg Indian Journal of Physiology and Pharmacology. Vol. 17, Pg. 31, 1973.
intravenous-mouse LD50 81 mg/kg BEHAVIORAL: TREMOR
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Farmakologiya i Toksikologiya Vol. 26, Pg. 10, 1963.
oral-mouse LD50 60 mg/kg Meditsinskii Zhurnal Uzbekistana. Vol. (3), Pg. 61, 1985.
unreported-mouse LD50 250 mg/kg "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980Vol. 8(1), Pg. 122, 1982.
intravenous-rat LD50 30 mg/kg Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 601 mg/kg BEHAVIORAL: ATAXIA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" Farmakologiya i Toksikologiya Vol. 26, Pg. 10, 1963.
subcutaneous-rat LD50 285 mg/kg Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for serotonin usage levels up to: | | | not for fragrance use.
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| Recommendation for serotonin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 3-(2- | aminoethyl)-1H-indol-5-ol | | 3-(beta- | aminoethyl)-5-hydroxyindole | | 3-(2- | aminoethyl)indol-5-ol | | | antemovis | | | hippophain | | | indol-5-ol, 3-(2-aminoethyl)- | | | substance DS | | | thrombocytin | | | thrombotonin | | | tryptamine, 5-hydroxy- |
Articles:
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