melissa officinalis flower/leaf/stem extract
extract of the flowers, leaves and stems of the balmint, melissa officinalis l., labiatae
 
Notes:
None found
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Name: melissa officinalis flower/leaf/stem extract
CAS Number: 84082-61-1 
ECHA EC Number: 282-007-0
Category: cosmetic, flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 2112 balm flower/leaf/stem extract (melissa officinalis)
FDA:No longer provide for the use of these seven synthetic flavoring substances
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: soothing agents
tonic
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Suppliers:
Lipotec USA
Actiphyte® of Balm Of Mint Extract
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic, flavor and fragrance agents
Recommendation for melissa officinalis flower/leaf/stem extract usage levels up to:
 PROHIBITED: Should not be used as a fragrance ingredient.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): -2000.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Scientific Opinion on the use of oregano and lemon balm extracts as a food additive
View page or View pdf
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: 1
 melissa officinalis flower/leaf/stem extract
Chemidplus: 0084082611
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References:
 melissa officinalis flower/leaf/stem extract
Pubchem (sid): 135284663
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 lemon balm
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Synonyms:
bee balm flower/leaf/stem extract
lemon balm flower/leaf/stem extract
sweet balm flower/leaf/stem extract
 balm flower/leaf/stem extract (melissa officinalis)
 balm lemon flower/leaf/stem extract (melissa officinalis)
actiphyte of balm of mint extract
 extract of the flowers, leaves and stems of the balmint, melissa officinalis l., labiatae
 melissa bicornis flower/leaf/stem extract
 melissa flower/leaf/stem extract (melissa officinalis)
 xiang feng hua flower/leaf/stem extract
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Articles:
PubMed: Anti-stress effects of lemon balm-containing foods.
PubMed: Melissa officinalis extract inhibits laser-induced choroidal neovascularization in a rat model.
PubMed: Comparison between effects of different doses of Melissa officinalis and atorvastatin on the activity of liver enzymes in hypercholesterolemia rats.
PubMed: Efficacy of Melissa officinalis in suppressing ventricular arrhythmias following ischemia-reperfusion of the heart: a comparison with amiodarone.
PubMed: Attachment and penetration of acyclovir-resistant herpes simplex virus are inhibited by Melissa officinalis extract.
PubMed: Healthy reduced-fat Bologna sausages enriched in ALA and DHA and stabilized with Melissa officinalis extract.
PubMed: Lemon balm extract causes potent antihyperglycemic and antihyperlipidemic effects in insulin-resistant obese mice.
PubMed: Comparison of Neuroprotective Effects of Melissa officinalis Total Extract and Its Acidic and Non-Acidic Fractions against A β-Induced Toxicity.
PubMed: Melissa officinalis and Passiflora caerulea infusion as physiological stress decreaser.
PubMed: Quality consistency evaluation of Melissa officinalis L. commercial herbs by HPLC fingerprint and quantitation of selected phenolic acids.
PubMed: Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
PubMed: An evaluation of the inhibitory effects against rotavirus infection of edible plant extracts.
PubMed: Anxiolytic and antidepressant-like effects of Melissa officinalis (lemon balm) extract in rats: Influence of administration and gender.
PubMed: Melissa officinalis extract inhibits attachment of herpes simplex virus in vitro.
PubMed: Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances.
PubMed: In vitro amoebicidal activities of Satureja cuneifolia and Melissa officinalis on Acanthamoeba castellanii cysts and trophozoites.
PubMed: Protective effect of Melissa officinalis aqueous extract against Mn-induced oxidative stress in chronically exposed mice.
PubMed: Anti-proliferative effect of Melissa officinalis on human colon cancer cell line.
PubMed: Evaluation of the genotoxic and antigenotoxic potential of Melissa officinalis in mice.
PubMed: The effects of powdered fertilized eggs on depression.
PubMed: Inhibition of HIV-1 infection by aqueous extracts of Prunella vulgaris L.
PubMed: The anti-angiogenic herbal extracts Ob-X from Morus alba, Melissa officinalis, and Artemisia capillaris suppresses adipogenesis in 3T3-L1 adipocytes.
PubMed: Neuroprotective properties of melissa officinalis L. Extract against ecstasy-induced neurotoxicity.
PubMed: "High in omega-3 fatty acids" bologna-type sausages stabilized with an aqueous-ethanol extract of Melissa officinalis.
PubMed: Effects of Melissa officinalis L. (lemon balm) extract on neurogenesis associated with serum corticosterone and GABA in the mouse dentate gyrus.
PubMed: Phenolic composition and antioxidant properties of some traditionally used medicinal plants affected by the extraction time and hydrolysis.
PubMed: Assessment of the antioxidant potential of selected plant extracts--in vitro and in vivo experiments on pork.
PubMed: Effect of lyophilized water extracts of Melissa officinalis on the stability of algae and linseed oil-in-water emulsion to be used as a functional ingredient in meat products.
PubMed: Selenium, iodine, omega-3 PUFA and natural antioxidant from Melissa officinalis L.: a combination of components from healthier dry fermented sausages formulation.
PubMed: Effects of chronic administration of Melissa officinalis L. extract on anxiety-like reactivity and on circadian and exploratory activities in mice.
PubMed: Neuroprotective and neurological properties of Melissa officinalis.
PubMed: Composition of the fresh leaves and stems of Melissa officinalis and evaluation of skin irritation in a reconstituted human epidermis model.
PubMed: Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice.
PubMed: Bioassay-guided fractionation of lemon balm (Melissa officinalis L.) using an in vitro measure of GABA transaminase activity.
PubMed: Acetylcholinesterase inhibitory guided fractionation of Melissa officinalis L.
PubMed: Inhibitory activity of Melissa officinalis L. extract on Herpes simplex virus type 2 replication.
PubMed: Antioxidant effects of different extracts from Melissa officinalis, Matricaria recutita and Cymbopogon citratus.
PubMed: Endothelium-dependent induction of vasorelaxation by Melissa officinalis L. ssp. officinalis in rat isolated thoracic aorta.
PubMed: [Advances on the effects of the compounds of a phytotherapic agent (COLIMIL) on upper gastrointestinal transit in mice].
PubMed: Radical scavenging, antibacterial, and antiproliferative activities of Melissa officinalis L. extracts.
PubMed: Aqueous extracts from peppermint, sage and lemon balm leaves display potent anti-HIV-1 activity by increasing the virion density.
PubMed: Effects of traditionally used anxiolytic botanicals on enzymes of the gamma-aminobutyric acid (GABA) system.
PubMed: Effects of the herbal formulation ColiMil on upper gastrointestinal transit in mice in vivo.
PubMed: The psychopharmacology of European herbs with cognition-enhancing properties.
PubMed: Larvicidal activity of some Labiatae (Lamiaceae) plant extracts from Turkey.
PubMed: The in vitro screening for acetylcholinesterase inhibition and antioxidant activity of medicinal plants from Portugal.
PubMed: Selective extraction of derivates of p-hydroxy-benzoic acid from plant material by using a molecularly imprinted polymer.
PubMed: A randomized double-blind placebo-controlled trial of a standardized extract of Matricariae recutita, Foeniculum vulgare and Melissa officinalis (ColiMil) in the treatment of breastfed colicky infants.
PubMed: Protective role of Melissa officinalis L. extract on liver of hyperlipidemic rats: a morphological and biochemical study.
PubMed: Screening of traditionally used Lebanese herbs for neurological activities.
PubMed: Antiviral activity of the volatile oils of Melissa officinalis L. against Herpes simplex virus type-2.
PubMed: Antioxidant activity of supercritical extract of Melissa officinalis subsp. officinalis and Melissa officinalis subsp. inodora.
PubMed: Traditional medicine in Sakarya province (Turkey) and antimicrobial activities of selected species.
PubMed: Attenuation of laboratory-induced stress in humans after acute administration of Melissa officinalis (Lemon Balm).
PubMed: The effect of the Melissa officinalis extract on immune response in mice.
PubMed: Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties.
PubMed: Antibacterial activity of medicinal plant extracts against periodontopathic bacteria.
PubMed: Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial.
PubMed: Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm).
PubMed: Balm mint extract (Lo-701) for topical treatment of recurring herpes labialis.
PubMed: Dry plant extracts loaded on fumed silica for direct compression: preparation and preformulation.
PubMed: Protective effects of the aerial parts of Salvia officinalis, Melissa Officinalis and Lavandula angustifolia and their constituents against enzyme-dependent and enzyme-independent lipid peroxidation.
PubMed: Anti-HIV-1 activity of herbs in Labiatae.
PubMed: The substances of plant origin that inhibit protein biosynthesis.
PubMed: Screening of medicinal plants for induction of somatic segregation activity in Aspergillus nidulans.
PubMed: Local therapy of herpes simplex with dried extract from Melissa officinalis.
PubMed: Neurotropic action of the hydroalcoholic extract of Melissa officinalis in the mouse.
PubMed: The inhibitory effect of rosmarinic acid on complement involves the C5 convertase.
PubMed: A simple method for screening of fresh plant material for glycosidic bound volatile compounds.
PubMed: [Comparative studies of the sensitizing capacity of drugs used in herpes simplex].
PubMed: The components of Melissa officinalis L. that influence protein biosynthesis in-vitro.
PubMed: ANTIVIRAL ACTIVITY OF MELISSA OFFICINALIS (LEMON BALM) EXTRACT.
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