penicillinase from bacillus subtilis
 
Notes:
Used as a food additive [EAFUS]
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FDA internal no.: 977090-13-3 
Category: enzyme preparations and microorganisms
 
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FDA Mainterm (SATF):977090-13-3 ; PENICILLINASE FROM BACILLUS SUBTILIS
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: enzyme preparations and microorganisms
Recommendation for penicillinase from bacillus subtilis usage levels up to:
 not for fragrance use.
 
Recommendation for penicillinase from bacillus subtilis flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0977090133
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References:
Pubchem (cas): 977090-13-3
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): Search
FooDB: FDB010029
FDA Listing of Food Additive Status: View
VCF-Online: VCF Volatile Compounds in Food
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 bacillus subtilis
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 penicillinase
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Synonyms:
 penicillinase from bacillus subtilis
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Articles:
PubMed: Heterologous protein secretion in Lactococcus lactis is enhanced by the Bacillus subtilis chaperone-like protein PrsA.
PubMed: In vitro and in vivo antipseudomonal activity, acute toxicity, and mode of action of a newly synthesized fluoroquinolonyl ampicillin derivative.
PubMed: Beta-lactamase genes of the penicillin-susceptible Bacillus anthracis Sterne strain.
PubMed: Investigation of oxacillin-hydrolyzing beta-lactamase in borderline methicillin-resistant clinical isolates of Staphylococcus aureus.
PubMed: A method for demonstrating gene essentiality in Staphylococcus aureus.
PubMed: Detection of borreliacidal antibodies in Lyme borreliosis patient sera containing antimicrobial agents.
PubMed: Role of enzymes of homologous recombination in illegitimate plasmid recombination in Bacillus subtilis.
PubMed: The expression of a plasmid-specified exported protein causes structural plasmid instability in Bacillus subtilis.
PubMed: Antibodies to meningococcal class 1 outer-membrane protein and its variable regions in patients with systemic meningococcal disease.
PubMed: Simple bacteriological and thin-layer chromatographic methods for determination of individual drug concentrations treated with penicillin-G in combination with one of the aminoglycosides.
PubMed: An efficient expression and secretion system based on Bacillus subtilis phage phi 105 and its use for the production of B. cereus beta-lactamase I.
PubMed: Site-directed mutagenesis and substrate-induced inactivation of beta-lactamase I.
PubMed: Translational coupling in a penP-lacZ gene fusion in Bacillus subtilis and Escherichia coli: use of AUA as a restart codon.
PubMed: Bioassay of teicoplanin in serum containing rifampin or a beta-lactam antibiotic.
PubMed: Mutants of Bacillus subtilis defective in protein export.
PubMed: Cloning and nucleotide sequence of the penicillinase antirepressor gene penJ of Bacillus licheniformis.
PubMed: Disguise of antibiotics.
PubMed: Structural plasmid instability in recombination- and repair-deficient strains of Bacillus subtilis.
PubMed: Some factors affecting the copy number of specific plasmids in Bacillus species.
PubMed: Nucleotide sequence of the penicillinase repressor gene penI of Bacillus licheniformis and regulation of penP and penI by the repressor.
PubMed: The bacteriology of dog bite wounds on initial presentation.
PubMed: Identification of a positive retroregulator that stabilizes mRNAs in bacteria.
PubMed: Construction of high, intermediate and low-copy-number promoter-probe plasmids for Bacillus subtilis.
PubMed: Antibiotic identification by high voltage electrophoresis bioautography.
PubMed: Cloning and sequencing of the beta-lactamase I gene of Bacillus cereus 5/B and its expression in Bacillus subtilis.
PubMed: Effect of in vitro DNA rearrangement in the NH2-terminal region of the penicillinase gene from Bacillus licheniformis on the mode of expression in Bacillus subtilis.
PubMed: Penicillinase inactivates kanamycin in the presence of carbenicillin.
PubMed: Cloning and expression of the Escherichia coli D-xylose isomerase gene in Bacillus subtilis.
PubMed: Processing of Bacillus cereus 569/H beta-lactamase I in Escherichia coli and Bacillus subtilis.
PubMed: Use of the Escherichia coli lac repressor and operator to control gene expression in Bacillus subtilis.
PubMed: Biosynthesis of Bacillus licheniformis penicillinase in Escherichia coli and in Bacillus subtilis.
PubMed: Construction of penP delta 1, Bacillus licheniformis 749/C beta-lactamase lacking site for lipoprotein modification. Expression in Escherichia coli and Bacillus subtilis.
PubMed: Comparative studies on extracellular penicillinases of the same structural gene, penP, expressed in Bacillus licheniformis and Bacillus subtilis.
PubMed: Molecular cloning and nucleotide sequence of the type I beta-lactamase gene from Bacillus cereus.
PubMed: Transcriptional analyses of the Bacillus licheniformis penP gene.
PubMed: Cloning of the genes for penicillinase, penP and penI, of Bacillus licheniformis in some vector plasmids and their expression in Escherichia coli, Bacillus subtilis, and Bacillus licheniformis.
PubMed: Molecular cloning and expression of Bacillus licheniformis beta-lactamase gene in Escherichia coli and Bacillus subtilis.
PubMed: Detection of penicillins in the sera of 'healthy' blood donors.
PubMed: Export of extracellular levansucrase by Bacillus subtilis: inhibition by cerulenin and quinacrine.
PubMed: [Testing the sterility of injection preparations of penicillin series antibiotics].
PubMed: Secretion of lipids induced by inhibition of peptidoglycan synthesis in streptococci.
PubMed: Rapid bioassay for clindamycin alone and in the presence of aminoglycoside antibiotics.
PubMed: [Characteristics of determining the microbial contamination of penicillin series antibiotic powders and tablets].
PubMed: Penicillin-binding proteins of bacteria.
PubMed: [Resistance to beta-lactam antibiotics and aminoglycosides in gram negative bacteria. 2. Mechanism of resistance (author's transl)].
PubMed: The formation of functional penicillin-binding proteins.
PubMed: Beta-lactamase assays.
PubMed: Binding of (14C)penicillin G to the membrane-bound and the purified D-alanine carboxypeptidases from Bacillus stearothermophilus and Bacillus subtilis and its release.
PubMed: Progress of competence development in Bacillus subtilis.
PubMed: Total synthesis of bisnorpenicillin V.
PubMed: Pirazocillin: a new acid and penicillinase resistant semisynthetic penicillin.
PubMed: Effect of penicillin irradiation on bacterial growth and penicillin resistance.
PubMed: Specific assay of gentamicin in the presence of penicillins and cephalosporins. Use of commercially manufactured beta-lactamases.
PubMed: An enzyme preparation inactivating all penicillins and cephalosporins.
PubMed: A rapid micro-assay of gentamicin, kanamycin or streptomycin in serum containing penicillins or cephalosporins.
PubMed: [Gentamicin in purulent meningitis].
PubMed: [Interspecies transduction of determinants of penicillinase activity in Bacillus licheniformis and Bacillus subtilis].
PubMed: Measurement of beta-lactamase activity and rate of inactivation of penicillins by a pH-stat alkalimetric titration method.
PubMed: Multiple penicillin-binding components in Bacillus subtilis, Bacillus cereus, Staphylococcus aureus, and Escherichia coli.
PubMed: Electron microscopic study of the secretion of some bacterial enzymes and toxins.
PubMed: [Spectrophotometric determination of the hydrolysis of beta-lactam ring in penicillins].
PubMed: [Use of antipenicillinase serums for the inhibition of penicillinase activity].
PubMed: An introspective view of penicillinase.
PubMed: Investigation of the penicillinase activity in L colonies of Staphylococcus aureus.
PubMed: Biosynthesis of the peptidoglycan of bacterial cell walls. XVI. The reversible fixation of radioactive penicillin G to the D-alanine carboxypeptidase of Bacillus subtilis.
PubMed: Biosynthesis of the peptidoglycan of bacterial cell walls. XV. The binding of radioactive penicillin to the particulate enzyme preparation of Bacillus subtilis and its reversal with hydroxylamine or thiols.
PubMed: Possible involvement of beta-lactamase in sporulation in Bacillus cereus.
PubMed: Procedures for the assay of carbenicillin in body fluids.
PubMed: Enzyme and bacteriophage concentration by membrane filtration.
PubMed: [Biologically active metabolites of benzylpenicillin observed in guinea pigs].
PubMed: Characteristics of secretion of penicillinase, alkaline phosphatase, and nuclease by Bacillus species.
PubMed: [Problems posed by the control of products containing several antibiotics].
PubMed: A penicillinase-specific ribonucleic acid component from Bacillus cereus. I. Ribonucleic acid extraction and definition of the in vivo test system.
PubMed: Penicillin production and its mode of inheritance in Aspergillus nidulans.
PubMed: [Liberation of extracellular penicillinase during the process of enzyme induction in penicillase producing bacteria].
PubMed: [A comparative immunologic study of penicillinase extracted from various microorganisms].
PubMed: [Regularities of the induction of enzyme synthesis by penicillin age-producing cultures of Staph. aureus, Bac. cereus 569, Bac. subtilis].
PubMed: Naphcillin and its microbiological study.
PubMed: [Relation of the penicillin sensitivity of penicillinase-producing strains of Bacillus subtilis to the rate of their spore germination].
PubMed: THE INTERACTION OF PENICILLINASE WITH PENICILLINS. 3. COMPARISON OF EXOPENICILLINASE PREPARATIONS OF VARIOUS ORIGINS.
PubMed: [COMPARATIVE RESISTANCE OF SEMI-SYNTHETIC PENICILLINS TO PENICILLINASE OF VARIOUS ORIGINS].
PubMed: PENICILLIN RESISTANCE OF COMPETENT CELLS IN DEOXYRIBONUCLEIC ACID TRANSFORMATION OF BACILLUS SUBTILIS.
PubMed: THE NATURE OF THE INSENSITIVITY OF GRAM-NEGATIVE BACTERIA TOWARDS PENICILLINS.
PubMed: THE DIFFERENTIAL EFFECT OF ACTINOMYCIN D ON THE BIOSYNTHESIS OF ENZYMES IN BACILLUS SUBTILIS AND BACILLUS CEREUS.
PubMed: THE PH VALUE AT THE SURFACE OF BACILLUS SUBTILIS.
PubMed: MICROBIAL DEGRADATION OF CEPHALOSPORIN C.
PubMed: A STUDY OF PURIFICATION AND PROPERTIES OF BACILLUS SUBTILIS EXOPENICILLINASE.
PubMed: [Preparation of penicillinase from Bacillus subtilis (of Indian origin) and from Bacillus cereus, strain 569 N. R. R. L].
PubMed: The mechanism of liberation of penicillinase from Bacillus subtilis.
PubMed: The measurement of the liberation of penicillinase from Bacillus subtilis.
PubMed: The location of cell-bound penicillinase in Bacillus subtilis.
PubMed: Staphylococcal penicillinase. I. Inhibition and stimulation of activity.
PubMed: [Penicillinase synthesis by certain sporogenous microorganisms].
PubMed: Laboratory studies on the purified penicillinase of Bacillus subtilis.
PubMed: An immunological study of Bacillus subtilis penicillinases.
PubMed: [Research on penicillinase biosynthesis].
PubMed: A comparison of the properties of penicillinase produced by Bacillus subtilis and Bacillus cereus with and without addition of penicillin.
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