milk clotting enzyme from mucor pusillus l.
 
Notes:
Used as a food additive [EAFUS]
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FDA internal no.: 977017-75-6 
Category: enzyme preparations and microorganisms
 
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FDA Mainterm (SATF):977017-75-6 ; MILK CLOTTING ENZYME FROM MUCOR PUSILLUS L.
FDA Regulation:
FDA PART 173 -- SECONDARY DIRECT FOOD ADDITIVES PERMITTED IN FOOD FOR HUMAN CONSUMPTION
Subpart B--Enzyme Preparations and Microorganisms
Sec. 173.150 Milk-clotting enzymes, microbial.
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: enzyme preparations and microorganisms
Recommendation for milk clotting enzyme from mucor pusillus l. usage levels up to:
 not for fragrance use.
 
Recommendation for milk clotting enzyme from mucor pusillus l. flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Explanatory Note for the Guidance of the Scientific Panel of Food Contact Material, Enzymes, Flavourings and Processing Aids (CEF) on the Submission of a Dossier on Food Enzymes
View page or View pdf
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0977017756
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References:
Pubchem (sid): 135348830
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): Search
FooDB: FDB009886
FDA Listing of Food Additive Status: View
VCF-Online: VCF Volatile Compounds in Food
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 mucor pusillus
Search  PMC Picture
 rhizomucor pusillus
Search  PMC Picture
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Synonyms:
 rhizomucor pusillus rennet
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Articles:
PubMed: Molecular analysis of NAD(+)-dependent xylitol dehydrogenase from the zygomycetous fungus Rhizomucor pusillus and reversal of the coenzyme preference.
PubMed: Identification and characterization of d-xylose reductase involved in pentose catabolism of the zygomycetous fungus Rhizomucor pusillus.
PubMed: First case report of bloodstream infection by Rhizomucor pusillus in a child with hemophagocytic lymphohistiocytosis.
PubMed: First Detection of TR46/Y121F/T289A and TR34/L98H Alterations in Aspergillus fumigatus Isolates from Azole-Naive Patients in Denmark despite Negative Findings in the Environment.
PubMed: Rapid detection and identification of mucormycetes in bronchoalveolar lavage samples from immunocompromised patients with pulmonary infiltrates by use of high-resolution melt analysis.
PubMed: Serial monitoring of Mucorales DNA load in serum samples of a patient with disseminated mucormycosis after allogeneic bone marrow transplantation.
PubMed: Isavuconazole treatment of a patient with disseminated mucormycosis.
PubMed: Onychomycosis due to rhizomucor in psoriatic patient with HIV infection.
PubMed: [Mixed invasive fungal infection due to Rhizomucor pusillus and Aspergillus niger in an immunocompetent patient.]
PubMed: Biotransformation and improved enzymatic extraction of chlorogenic acid from coffee pulp by filamentous fungi.
PubMed: Production, Purification, and Characterization of Polygalacturonase from Rhizomucor pusillus Isolated from Decomposting Orange Peels.
PubMed: Biotransformation of progesterone by Absidia griseolla var. igachii and Rhizomucor pusillus.
PubMed: Application of a multiplex suspension array for rapid and simultaneous identification of clinically important mold pathogens.
PubMed: Breakthrough filamentous fungal infections in pediatric hematopoetic stem cell transplant and oncology patients receiving caspofungin.
PubMed: Pulmonary, rhino-orbital and cutaneous mucormycosis caused by Rhizomucor pusillus in an immunocompromised patient.
PubMed: Potential of thermophilic fungus Rhizomucor pusillus NRRL 28626 in biotransformation of antihelmintic drug albendazole.
PubMed: In vitro interaction of caspofungin and immunosuppressives against agents of mucormycosis.
PubMed: Synthesis and properties of a novel biosuperabsorbent from alkali soluble Rhizomucor pusillus proteins.
PubMed: Biofilm formation by zygomycetes: quantification, structure and matrix composition.
PubMed: Mucormycosis caused by unusual mucormycetes, non-Rhizopus, -Mucor, and -Lichtheimia species.
PubMed: Zygomycosis presenting a major clinical challenge: case report on Rhizomucor pusillus infection in a stem-cell-transplant recipient.
PubMed: Disseminated Rhizomucor pusillus causing early multiorgan failure during hematopoietic stem cell transplantation for severe aplastic anemia.
PubMed: Simultaneous detection and identification of Aspergillus and mucorales species in tissues collected from patients with fungal rhinosinusitis.
PubMed: Temperature shifts for extraction and purification of zygomycetes chitosan with dilute sulfuric acid.
PubMed: Molecular detection and identification of zygomycetes species from paraffin-embedded tissues in a murine model of disseminated zygomycosis: a collaborative European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Fungal Infection Study Group (EFISG) evaluation.
PubMed: In vitro interaction of posaconazole with calcineurin inhibitors and sirolimus against zygomycetes.
PubMed: Zygomycotic lymphadenitis in slaughtered feedlot cattle.
PubMed: Different drying technologies and alternation of mycobiots in the raw material of Hyssopus officinalis L.
PubMed: Isolation and identification of Rhizomucor pusillus from pleural zygomycosis in an immunocompetent patient.
PubMed: Spectrum of zygomycete species identified in clinically significant specimens in the United States.
PubMed: Combined antifungal therapy, iron chelation and surgical resection as treatment of hepatic zygomycosis in a patient with haematological malignancy.
PubMed: Determination of glucosamine and N-acetyl glucosamine in fungal cell walls.
PubMed: Protease production by different thermophilic fungi.
PubMed: [Invasive zygomycosis in patients treated for haematological malignancies].
PubMed: Extraction and precipitation of chitosan from cell wall of zygomycetes fungi by dilute sulfuric acid.
PubMed: Biosorption of simulated dyed effluents by inactivated fungal biomasses.
PubMed: Toxic micromycetes in grain raw material during its processing.
PubMed: Identification and retting efficiencies of fungi isolated from dew-retted flax in the United States and europe.
PubMed: Molecular identification of zygomycetes from culture and experimentally infected tissues.
PubMed: Production of saccharogenic and dextrinogenic amylases by Rhizomucor pusillus A 13.36.
PubMed: Fungal survival during anaerobic digestion of organic household waste.
PubMed: Molecular identification of Rhizomucor pusillus as a cause of sinus-orbital zygomycosis in a patient with acute myelogenous leukemia.
PubMed: Decolorization of bleach plant effluent by mucoralean and white-rot fungi in a rotating biological contactor reactor.
PubMed: Zygomycosis.
PubMed: In vitro susceptibility of 15 strains of zygomycetes to nine antifungal agents as determined by the NCCLS M38-A microdilution method.
PubMed: Susceptibility of filamentous fungi to voriconazole tested by two microdilution methods.
PubMed: Differentiation of Rhizomucor species on the basis of their different sensitivities to lovastatin.
PubMed: A multicopy vector system for genetic studies in Mucor circinelloides and other zygomycetes.
PubMed: Substrate specificity of the alpha-L-arabinofuranosidase from Rhizomucor pusillus HHT-1.
PubMed: The production of D-xylose by enzymatic hydrolysis of agricultural wastes.
PubMed: Cure of pulmonary Rhizomucor pusillus infection in a patient with hairy-cell leukemia: role of liposomal amphotericin B and GM-CSF.
PubMed: Microbial, chemical and physical aspects of citrus waste composting.
PubMed: Animal models of zygomycosis--Absidia, Rhizopus, Rhizomucor, and Cunninghamella.
PubMed: Physicochemical properties of a novel alpha-L-arabinofuranosidase from Rhizomucor pusillus HHT-1.
PubMed: Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus.
PubMed: Liposomal amphotericin B and surgery in the successful treatment of invasive pulmonary mucormycosis in a patient with acute T-lymphoblastic leukemia.
PubMed: Replacements of amino acid residues at subsites and their effects on the catalytic properties of Rhizomucor pusillus pepsin, an aspartic proteinase from Rhizomucor pusillus.
PubMed: Determination of the disulfide structure of sillucin, a highly knotted, cysteine-rich peptide, by cyanylation/cleavage mass mapping.
PubMed: Intraspecific variation in two species of Rhizomucor assessed by random amplified polymorphic DNA analysis.
PubMed: Phylogeny and PCR identification of clinically important Zygomycetes based on nuclear ribosomal-DNA sequence data.
PubMed: Characterization of an alg2 mutant of the zygomycete fungus Rhizomucor pusillus.
PubMed: Genetic transformation of a Rhizomucor pusillus mutant defective in asparagine-linked glycosylation: production of a milk-clotting enzyme in a less-glycosylated form.
PubMed: [Fungal flora in chicken stalls and its etiopathogenic importance for humans and animals].
PubMed: Rhizomucor pusillus mucormycosis combined with chlamydiosis in an African grey parrot (Psittacus erithacus erithacus).
PubMed: Characterization of alg2 encoding a mannosyltransferase in the zygomycete fungus Rhizomucor pusillus.
PubMed: Differentiation of Rhizomucor species by carbon source utilization and isoenzyme analysis.
PubMed: Structure of asparagine-linked oligosaccharides of an aspartic proteinase from the zygomycete fungus Rhizomucor pusillus.
PubMed: Incidence and detection of thermotolerant and thermophilic fungi from maize with particular reference to Thermoascus species.
PubMed: Site-directed mutagenesis of conserved Trp39 in Rhizomucor pusillus pepsin: possible role of Trp39 in maintaining Tyr75 in the correct orientation for maximizing catalytic activity.
PubMed: Involvement of a residue at position 75 in the catalytic mechanism of a fungal aspartic proteinase, Rhizomucor pusillus pepsin. Replacement of tyrosine 75 on the flap by asparagine enhances catalytic efficiency.
PubMed: Integrative transformation of the zygomycete Rhizomucor pusillus by homologous recombination.
PubMed: [Zygomycosis: review of 16 cases].
PubMed: Immunohistochemical diagnosis of systemic bovine zygomycosis by murine monoclonal antibodies.
PubMed: [Disseminated aspergillosis and mucormycosis. A case report].
PubMed: Crystallization and preliminary X-ray structure solution of Rhizomucor miehei aspartic proteinase.
PubMed: Zygospores: the last word in identification of rare or atypical zygomycetes isolated from clinical specimens.
PubMed: Extracellular amylase activities of Rhizomucor pusillus and Humicola lanuginosa at initial stages of growth.
PubMed: Mycoflora and natural occurrence of mycotoxins in tobacco from cigarettes in Egypt.
PubMed: Infection due to Rhizomucor pusillus: report of four cases in patients with leukemia and review.
PubMed: Mycoflora and mycotoxin of hazelnut (Corylus avellana L.) and walnut (Juglans regia L.) seeds in Egypt.
PubMed: Survey of mycoflora and mycotoxins in Egyptian soybean seeds.
PubMed: [Inhibitory effects of organic acids and salts on selected micromycetes].
PubMed: Keratinolysis by Absidia cylindrospora and Rhizomucor pusillus: biochemical proof.
PubMed: Fungi associated with bovine abortion in the northern plains states (USA).
PubMed: Systemic zygomycosis: nosocomial infection by Rhizomucor pusillus.
PubMed: Studies on the mycoflora of Aswan High Dam Lake, Egypt: monthly variations.
PubMed: Fungal flora associated with combine harvester wheat and sorghum dusts from Egypt.
PubMed: Cellulitis caused by Rhizomucor pusillus in a diabetic patient receiving continuous insulin infusion pump therapy.
PubMed: Indirect enzyme-linked immunosorbent assay for zygomycosis.
PubMed: Storage temperature and viability of sporangiospores of potentially human pathogenic species of Rhizomucor from Nigerian tobacco.
PubMed: Fungal flora of poultry feedstuff ingredients.
PubMed: Separation of fungal propagules by partition in aqueous polymer two-phase systems.
PubMed: Mucormycotic infection in mice following prolonged incubation of spores in vivo and the role of spore agglutinating antibodies on spore germination.
PubMed: Passive immunization in murine mucormycosis.
PubMed: Immunodiffusion and complement fixation assays with sera from mucormycotic-infected mice.
PubMed: Nosocomial infection by Rhizomucor pusillus in a clinical haematology unit.
PubMed: Murine model of pulmonary mucormycosis in cortisone-treated mice.
PubMed: Experimental cerebral zygomycosis in alloxan-diabetic rabbits: variation in virulence among zygomycetes.
PubMed: [Cerebral mucormycosis in the cat caused by Mucor pusillus].
PubMed: Induced azygospore formation in Mucor (Rhizomucor) pusillus by Absidia corymbifera.
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