lipase from aspergillus oryzae
lipase derived from aspergillus oryzae carrying a gene encoding lipase from fusarium oxysporum
 
Notes:
Used as a food additive [EAFUS]
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FDA internal no.: 977031-68-7 
Category: enzyme preparations and microorganisms
 
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 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 43 Lipase derived from Aspergillus oryzae carrying a gene encoding lipase from Thermomyces lanuginosus View - notice PDF
GRN 75 Lipase derived from Aspergillus oryzae carrying a gene encoding lipase from Fusarium oxysporum View - notice PDF
GRN 103 Lipase enzyme preparation from Aspergillus oryzae carrying a gene constructed from a modified Thermomyces lanuginosus lipase gene and a portion of the Fusarium oxysporum lipase gene View - notice PDF
GRN 113 Lipase enzyme preparation from Aspergillus oryzae View - notice PDF
FDA Mainterm (SATF):977031-68-7 ; LIPASE FROM ASPERGILLUS ORYZAE
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: enzyme preparations and microorganisms
Recommendation for lipase from aspergillus oryzae usage levels up to:
 not for fragrance use.
 
Recommendation for lipase from aspergillus oryzae flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Scientific Opinion on lipase from a genetically modified strain of Aspergillus oryzae (strain NZYM-AL)
View page or View pdf
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0977031687
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References:
Pubchem (cas): 977031-68-7
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): Search
FooDB: FDB009736
FDA Listing of Food Additive Status: View
VCF-Online: VCF Volatile Compounds in Food
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 aspergillus oryzae
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 lipase
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Synonyms:
 lipase derived from aspergillus oryzae carrying a gene encoding lipase from fusarium oxysporum
 lipase derived from aspergillus oryzae carrying a gene encoding lipase from thermomyces lanuginosus
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Articles:
PubMed: Crystal structure of a feruloyl esterase belonging to the tannase family: a disulfide bond near a catalytic triad.
PubMed: Biochemical properties of a new cold-active mono- and diacylglycerol lipase from marine member Janibacter sp. strain HTCC2649.
PubMed: Dry entrapment of enzymes by epoxy or polyester resins hardened on different solid supports.
PubMed: A robust whole-cell biocatalyst that introduces a thermo- and solvent-tolerant lipase into Aspergillus oryzae cells: characterization and application to enzymatic biodiesel production.
PubMed: High-level extracellular production and characterization of Candida antarctica lipase B in Pichia pastoris.
PubMed: Hierarchical meso-macroporous silica grafted with glyoxyl groups: opportunities for covalent immobilization of enzymes.
PubMed: An integrative process model of enzymatic biodiesel production through ethanol fermentation of brown rice followed by lipase-catalyzed ethanolysis in a water-containing system.
PubMed: Production of biodiesel from plant oil hydrolysates using an Aspergillus oryzae whole-cell biocatalyst highly expressing Candida antarctica lipase B.
PubMed: Efficient heterologous expression and secretion in Aspergillus oryzae of a llama variable heavy-chain antibody fragment V(HH) against EGFR.
PubMed: Biocatalytic conversion of aloeresin A to aloesin.
PubMed: Functional analysis of FarA transcription factor in the regulation of the genes encoding lipolytic enzymes and hydrophobic surface binding protein for the degradation of biodegradable plastics in Aspergillus oryzae.
PubMed: Anti-obesity effect of a standardised ethanol extract from Curcuma longa L. fermented with Aspergillus oryzae in ob/ob mice and primary mouse adipocytes.
PubMed: A novel biocatalytic approach to acetylation of 1-β-D-arabinofuranosylcytosine by Aspergillus oryzae whole cell in organic solvents.
PubMed: Development of an Aspergillus oryzae whole-cell biocatalyst coexpressing triglyceride and partial glyceride lipases for biodiesel production.
PubMed: Highly efficient biodiesel production by a whole-cell biocatalyst employing a system with high lipase expression in Aspergillus oryzae.
PubMed: Display of both N- and C-terminal target fusion proteins on the Aspergillus oryzae cell surface using a chitin-binding module.
PubMed: Some biochemical and physical changes during the preparation of the enzyme-ripening sufu, a fermented product of soybean curd.
PubMed: Kinetic resolution of alpha-lipoic acid via enzymatic differentiation of a remote stereocenter.
PubMed: Improved production of raw starch degrading enzyme by Aspergillus oryzae F-30 using methyl glucoside sesqui-stearate.
PubMed: Preparation and comparative characterization of immobilized Aspergillus oryzae expressing Fusarium heterosporum lipase for enzymatic biodiesel production.
PubMed: New, efficient synthesis of oseltamivir phosphate (Tamiflu) via enzymatic desymmetrization of a meso-1,3-cyclohexanedicarboxylic acid diester.
PubMed: Role of N-terminal 28-amino-acid region of Rhizopus oryzae lipase in directing proteins to secretory pathway of Aspergillus oryzae.
PubMed: [Lipase-catalyzed production of biodiesel from high acid value waste oil with ultrasonic assistant].
PubMed: Effects of fermented soybean meal on digestive enzyme activities and intestinal morphology in broilers.
PubMed: Development of recombinant Aspergillus oryzae whole-cell biocatalyst expressing lipase-encoding gene from Candida antarctica.
PubMed: Preliminary studies on production of extracellular lipase by an isolate from soil : Aspergillus flavus oryzae.
PubMed: Chemometric analysis of in-line multi-wavelength fluorescence measurements obtained during cultivations with a lipase producing Aspergillus oryzae strain.
PubMed: Proteomic methods applied to the analysis of immobilized biocatalysts.
PubMed: Functional expression of Candida antarctica lipase B in Eschericha coli.
PubMed: Olive-mill wastewaters: a promising substrate for microbial lipase production.
PubMed: Simultaneous display of bacterial and fungal lipases on the cell surface of Bacillus subtilis.
PubMed: Accumulation of a recombinant Aspergillus oryzae lipase artificially localized on the Bacillus subtilis cell surface.
PubMed: Change in hyphal morphology of Aspergillus oryzae during fed-batch cultivation.
PubMed: Acidolysis between triolein and short-chain fatty acid by lipase in organic solvents.
PubMed: Lipase production by recombinant strains of Aspergillus niger expressing a lipase-encoding gene from Thermomyces lanuginosus.
PubMed: Enantioselective transesterification using immobilized Aspergillus oryzae overexpressing lipase.
PubMed: New cationic exchanger support for reversible immobilization of proteins.
PubMed: Protein expression and secretion in the yeast Yarrowia lipolytica.
PubMed: Cloning of the Aspergillus oryzae 5-aminolevulinate synthase gene and its use as a selectable marker.
PubMed: Cloning and sequencing of the triacylglycerol lipase gene of Aspergillus oryzae and its expression in Escherichia coli.
PubMed: Using DNA-tagged mutagenesis to improve heterologous protein production in Aspergillus oryzae.
PubMed: Production of extracellular lipases by Penicillium cyclopium purification and characterization of a partial acylglycerol lipase.
PubMed: Reversible enzyme immobilization via a very strong and nondistorting ionic adsorption on support-polyethylenimine composites.
PubMed: Molecular cloning and expression of the gene encoding a phospholipase A1 from Aspergillus oryzae.
PubMed: Purification and characterization of triacylglycerol lipase from Aspergillus oryzae.
PubMed: Characteristics of antibody responses induced in mice by protein allergens.
PubMed: Efficient expression of mono- and diacylglycerol lipase gene from Penicillium camembertii U-150 in Aspergillus oryzae under the control of its own promoter.
PubMed: Cloning and nucleotide sequence of the mono- and diacylglycerol lipase gene (mdlB) of Aspergillus oryzae.
PubMed: Safety evaluation of a lipase expressed in Aspergillus oryzae.
PubMed: Purification and characterization of a lipase from Aspergillus oryzae.
PubMed: Genome structure and nucleotide sequence of a lipolytic enzyme gene of Aspergillus oryzae.
PubMed: Serological responses induced in mice by immunogenic proteins and by protein respiratory allergens.
PubMed: Structure-function relationships in naturally occurring mutants of pancreatic lipase.
PubMed: An overview of the safety evaluation of the Rhizomucor miehei lipase enzyme.
PubMed: A structural domain (the lid) found in pancreatic lipases is absent in the guinea pig (phospho)lipase.
PubMed: Rhizomucor miehei triglyceride lipase is processed and secreted from transformed Aspergillus oryzae.
PubMed: [Premedication for sonography. Enzyme-paractol in comparison with a placebo].
PubMed: On a rabbit hyperlipemia induced by a fungic galactomannane peptide.
PubMed: [Experiences with substitution therapy using a new pancreatic enzyme of plant origin].
PubMed: Histamine induction and release following proteolytic enzyme exposure.
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