glucose isomerase from streptomyces olivochromogen
xylose isomerase from streptomyces olivochromogen
 
Notes:
Used as a food additive [EAFUS]
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FDA internal no.: 977090-07-5 
Category: enzyme preparations and microorganisms
 
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JECFA Food Additive: Glucose Isomerase from Streptomyces olivochromogen
FDA Mainterm (SATF):977090-07-5 ; GLUCOSE ISOMERASE FROM STREPTOMYCES OLIVOCHROMOGENES
FDA Regulation:
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1372 Insoluble glucose isomerase enzyme preparations.
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Physical Properties:
Appearance: white to brown granules or liquid (est)
Food Chemicals Codex Listed: No
Insoluble in:
 alcohol
 water
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: enzyme preparations and microorganisms
Recommendation for glucose isomerase from streptomyces olivochromogen usage levels up to:
 not for fragrance use.
 
Recommendation for glucose isomerase from streptomyces olivochromogen flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0977090075
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References:
Pubchem (sid): 135349804
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): Search
FooDB: FDB009498
FDA Listing of Food Additive Status: View
VCF-Online: VCF Volatile Compounds in Food
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 glucose isomerase
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 streptomyces olivochromogen
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Synonyms:
 xylose isomerase from streptomyces olivochromogen
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Articles:
PubMed: Probing the role of helix α1 in the acid-tolerance and thermal stability of the Streptomyces sp. SK Glucose Isomerase by site-directed mutagenesis.
PubMed: Engineering acidic Streptomyces rubiginosus D-xylose isomerase by rational enzyme design.
PubMed: Crystallization, solubility and thermodynamics of the highly thermostable glucose isomerase from Streptomyces sp. strain.
PubMed: A common mechanism underlying amyloid fibrillation and protein crystallization revealed by the effects of ultrasonication.
PubMed: Engineering xylose metabolism in triacylglycerol-producing Rhodococcus opacus for lignocellulosic fuel production.
PubMed: High-level overproduction of Thermobifida enzyme in Streptomyces lividans using a novel expression vector.
PubMed: Identification of critical residues for the activity and thermostability of Streptomyces sp. SK glucose isomerase.
PubMed: Optimization of Fermentation Medium for the Production of Glucose Isomerase Using Streptomyces sp. SB-P1.
PubMed: Role of invariant water molecules and water-mediated ionic interactions in D-xylose isomerase from Streptomyces rubiginosus.
PubMed: Glucose(xylose) isomerase production by Streptomyces sp. CH7 grown on agricultural residues.
PubMed: Monitoring and scoring counter-diffusion protein crystallization experiments in capillaries by in situ dynamic light scattering.
PubMed: Engineering of a xylose metabolic pathway in Rhodococcus strains.
PubMed: Engineered glucose isomerase from Streptomyces sp. SK is resistant to Ca²⁺ inhibition and Co²⁺ independent.
PubMed: An innovative biocatalyst for production of ethanol from xylose in a continuous bioreactor.
PubMed: Binding energy and catalysis by D-xylose isomerase: kinetic, product, and X-ray crystallographic analysis of enzyme-catalyzed isomerization of (R)-glyceraldehyde.
PubMed: Ligand-protein cross-docking with water molecules.
PubMed: Integrative gene cloning and expression system for Streptomyces sp. US 24 and Streptomyces sp. TN 58 bioactive molecule producing strains.
PubMed: Beneficial effect of solubility enhancers on protein crystal nucleation and growth.
PubMed: Deletion of xylR gene enhances expression of xylose isomerase in Streptomyces lividans TK24.
PubMed: Thermoinactivation mechanism of glucose isomerase.
PubMed: Characterization of the pH-dependent dissociation of a multimeric metalloprotein Streptomyces rubiginosus xylose isomerase by ESI FT-ICR mass spectrometry.
PubMed: The identification of (3R,4S)-5-fluoro-5-deoxy-D-ribulose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya.
PubMed: Cryogenic (<20 K) helium cooling mitigates radiation damage to protein crystals.
PubMed: Trehalose phosphorylase from Pleurotus ostreatus: characterization and stabilization by covalent modification, and application for the synthesis of alpha,alpha-trehalose.
PubMed: Involvement of alanine 103 residue in kinetic and physicochemical properties of glucose isomerases from Streptomyces species.
PubMed: High-pressure acceleration of the growth kinetics of glucose isomerase crystals.
PubMed: Optimizing crystal volume for neutron diffraction: D-xylose isomerase.
PubMed: Locating active-site hydrogen atoms in D-xylose isomerase: time-of-flight neutron diffraction.
PubMed: A quasi-Laue neutron crystallographic study of D-xylose isomerase.
PubMed: Expression of xylA genes encoding xylose isomerases from Escherichia coli and Streptomyces coelicolor in the methylotrophic yeast Hansenula polymorpha.
PubMed: Multi-frequency high-field EPR studies on metal-substituted xylose isomerase.
PubMed: Direct comparison of the crystal and solution structure of glucose/xylose isomerase from Streptomyces rubiginosus.
PubMed: Quantitative imaging by confocal scanning fluorescence microscopy of protein crystallization via liquid-liquid phase separation.
PubMed: Molecular cloning and expression of a thermostable xylose (glucose) isomerase gene, xylA, from Streptomyces chibaensis J-59.
PubMed: Engineering the substrate specificity of xylose isomerase.
PubMed: Chromatographic separation of nucleosides using a cross-linked xylose isomerase crystal stationary phase.
PubMed: Glucose isomerase of the Streptomyces sp. SK strain: purification, sequence analysis and implication of alanine 103 residue in the enzyme thermostability and acidotolerance.
PubMed: Novel reactions of L-rhamnose isomerase from Pseudomonas stutzeri and its relation with D-xylose isomerase via substrate specificity.
PubMed: Xylose isomerase in substrate and inhibitor michaelis states: atomic resolution studies of a metal-mediated hydride shift.
PubMed: A preliminary time-of-flight neutron diffraction study of Streptomyces rubiginosus D-xylose isomerase.
PubMed: SAD manganese in two crystal forms of glucose isomerase.
PubMed: [Correlation of conformational change with enzyme activity of glucose isomerase in denaturants monitored with high performance liquid chromatography].
PubMed: Effect of pH on simultaneous saccharification and isomerization by glucoamylase and glucose isomerase.
PubMed: Mechanism of action of D-xylose isomerase.
PubMed: Glucose-to-fructose conversion at high temperatures with xylose (glucose) isomerases from Streptomyces murinus and two hyperthermophilic Thermotoga species.
PubMed: [Overexpression and detection of the mutated glucose isomerase GIG138P and GIG138P-G247D in Streptomyces lividans].
PubMed: Construction of double-copy glucose isomerase gene engineering strain of Streptomyces diastaticus by homologous recombination.
PubMed: Site-specific integration of the double-mutation glucose isomerase (GIG138PG247D) gene in Streptomyces lividans and its stable expression.
PubMed: Rapid purification and biochemical characterization of glucose kinase from Streptomyces peucetius var. caesius.
PubMed: Molecular cloning of acid-stable glucose isomerase gene from Streptomyces olivaceoviridis E-86 by a simple two-step PCR method, and its expression in Escherichia coli.
PubMed: Isolation and characterization of a xylose-glucose isomerase from a new strain Streptomyces thermovulgaris 127, var. 7-86.
PubMed: Simultaneous catalysis and product separation by cross-linked enzyme crystals.
PubMed: Heterologous expression of the single-mutation glucose isomerase (GIG138P) gene in Streptomyces lividans and its genetic instability.
PubMed: Kinetics of glucose isomerization to fructose by immobilized glucose isomerase: anomeric reactivity of D-glucose in kinetic model.
PubMed: Characterization of acid-induced unfolding intermediates of glucose/xylose isomerase.
PubMed: [Glucose isomerase gene knock-out by denatured double-stranded DNA].
PubMed: Characterization of acid-stable glucose isomerase from Streptomyces sp., and development of single-step processes for high-fructose corn sweetener (HFCS) production.
PubMed: A bifunctional beta-xylosidase-xylose isomerase from Streptomyces sp. EC 10.
PubMed: Structure of xylose isomerase from Streptomyces diastaticus no. 7 strain M1033 at 1.85 A resolution.
PubMed: Structure of the human glycogen-associated protein phosphatase 1 regulatory subunit hGM: homology modeling revealed an (alpha/beta)8-barrel-like fold in the multidomain protein.
PubMed: Increasing the thermostability of D-xylose isomerase by introduction of a proline into the turn of a random coil.
PubMed: Stability of native and cross-linked crystalline glucose isomerase.
PubMed: Lowering the pH optimum of D-xylose isomerase: the effect of mutations of the negatively charged residues.
PubMed: Sequence similarity between xylose isomerase and replicase: another TIM-barrel in the replicase structure?
PubMed: High fructose syrups: evaluation of a new glucose isomerase from Streptomyces sp.
PubMed: Molecular cloning and expression of the glucose/xylose isomerase gene from Streptomyces sp. NCIM 2730 in Escherichia coli.
PubMed: The tentative (alpha/beta)8-barrel in the pathway of beta-carotene biosynthesis: lycopene cyclase has an amino acid sequence similar to that of xylose isomerase.
PubMed: Extranuclear expression of the bacterial xylose isomerase (xylA) and the UDP-glucose dehydrogenase (hasB) genes in yeast with Kluyveromyces lactis linear killer plasmids as vectors.
PubMed: Molecular and industrial aspects of glucose isomerase.
PubMed: Probing the roles of active site residues in D-xylose isomerase.
PubMed: Design, synthesis, and characterization of a potent xylose isomerase inhibitor, D-threonohydroxamic acid, and high-resolution X-ray crystallographic structure of the enzyme-inhibitor complex.
PubMed: [Promoter activity detection and transcription initiation site determination of the D-xylose isomerase gene of Streptomyces diastaticus strain No.7 M1033].
PubMed: [Glucose isomerase of S. violaceoniger. Fundamental and applied aspects].
PubMed: X-ray crystallographic structures of D-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis.
PubMed: Medium optimization for the production of glucose isomerase from thermophilic Streptomyces thermonitrificans.
PubMed: A structural role for arginine in proteins: multiple hydrogen bonds to backbone carbonyl oxygens.
PubMed: Structure determination of glucose isomerase from Streptomyces murinus at 2.6 A resolution.
PubMed: Optimization of enzyme ratios in a coimmobilized enzyme reactor for the analysis of D-xylose and D-xylulose in a flow system.
PubMed: Isotopic exchange plus substrate and inhibition kinetics of D-xylose isomerase do not support a proton-transfer mechanism.
PubMed: Role of the divalent metal ion in sugar binding, ring opening, and isomerization by D-xylose isomerase: replacement of a catalytic metal by an amino acid.
PubMed: Perturbing the metal site in D-xylose isomerase. Effect of mutations of His-220 on enzyme stability.
PubMed: The sequence of xylose isomerase gene from Streptomyces diastaticus No. 7 M1033.
PubMed: X- and Q-band EPR studies on the two Mn(2+)-substituted metal-binding sites of D-xylose isomerase.
PubMed: Binding characteristics of Mn2+, Co2+ and Mg2+ ions with several D-xylose isomerases.
PubMed: Evidence for the existence of isozymes of glucose isomerase from Streptomyces phaeochromogenes.
PubMed: Equilibrium kinetics of D-glucose to D-fructose isomerization catalyzed by glucose isomerase enzyme from Streptomyces phaeochromogenus.
PubMed: Organization and characterization of three genes involved in D-xylose catabolism in Lactobacillus pentosus.
PubMed: Genetic organization and regulation of the xylose degradation genes in Streptomyces rubiginosus.
PubMed: Immunoaffinity purification of glucose/xylose isomerase from Streptomyces.
PubMed: Kinetic studies of Mg(2+)-, Co(2+)- and Mn(2+)-activated D-xylose isomerases.
PubMed: Xylose (glucose) isomerase gene from the thermophile Thermus thermophilus: cloning, sequencing, and comparison with other thermostable xylose isomerases.
PubMed: Visible, EPR and electron nuclear double-resonance spectroscopic studies on the two metal-binding sites of oxovanadium (IV)-substituted D-xylose isomerase.
PubMed: A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 A Streptomyces rubiginosus structures with xylitol and D-xylose.
PubMed: Refinement of glucose isomerase from Streptomyces albus at 1.65 A with data from an imaging plate.
PubMed: Spectroscopic studies on the metal-ion-binding sites of Co2(+)-substituted D-xylose isomerase from Streptomyces rubiginosus.
PubMed: Catalytic mechanism of xylose (glucose) isomerase from Clostridium thermosulfurogenes. Characterization of the structural gene and function of active site histidine.
PubMed: Molecular cloning of the xylA gene encoding xylose isomerase from Streptomyces griseofuscus S-41: primary structure of the gene and its product.
PubMed: Localization of the essential histidine and carboxylate group in D-xylose isomerases.
PubMed: Identification of essential histidine residues in the active site of Escherichia coli xylose (glucose) isomerase.
PubMed: [Cloning and expression of E. coli glucose isomerase gene in Streptomyces lividans].
PubMed: Resistance of spores and vegetative cells of Streptomyces thermovulgaris strain 127 and the glucose isomerase produced by them to temperature and glutaraldehyde.
PubMed: Site-directed mutagenesis applied to glucose isomerase from Streptomyces violaceoniger and Streptomyces olivochromogenes.
PubMed: Single active-site histidine in D-xylose isomerase from Streptomyces violaceoruber. Identification by chemical derivatization and peptide mapping.
PubMed: Crystallographic studies of the mechanism of xylose isomerase.
PubMed: X-ray analysis of D-xylose isomerase at 1.9 A: native enzyme in complex with substrate and with a mechanism-designed inactivator.
PubMed: Reaction of Woodward's reagent K with D-xylose isomerases. Modification of an active site carboxylate residue.
PubMed: Crystallisation and preliminary analysis of glucose isomerase from Streptomyces albus.
PubMed: Mechanism of thermoinactivation of immobilized glucose isomerase.
PubMed: Streptomyces glucose/xylose isomerase has a single active site for glucose and xylose.
PubMed: [Effect of carbon and nitrogen source on the yield of D-glucose isomerase in Streptomyces roseocastaneus strain No. 336].
PubMed: Characterization of crystals of xylose isomerase from Streptomyces violaceoniger.
PubMed: Nucleotide sequence of the xylose isomerase gene from Streptomyces violaceoniger.
PubMed: Evidence for the essential histidine residue at the active site of glucose/xylose isomerase from Streptomyces.
PubMed: Metal ion binding to D-xylose isomerase from Streptomyces violaceoruber.
PubMed: Evidence for an essential histidine residue in D-xylose isomerases.
PubMed: Cultural stability of Streptomyces fradiae in the production of xylose isomerase: studies in shake flasks.
PubMed: [Glucose isomerase biosynthesis, the isolation of immobilized preparations and their characteristics in the continuous process of isomerization].
PubMed: Comparison of backbone structures of glucose isomerase from Streptomyces and Arthrobacter.
PubMed: The 3.0 A crystal structure of xylose isomerase from Streptomyces olivochromogenes.
PubMed: Location and purification of enzymes on polyacrylamide gels using dialyzable fluorescent markers.
PubMed: Safety evaluation of Streptomyces murinus glucose isomerase.
PubMed: Sequence of the Ampullariella sp. strain 3876 gene coding for xylose isomerase.
PubMed: Characterization and cloning of glucose isomerase from Streptomyces violaceoniger.
PubMed: [Kinetics of the assimilation of labelled carbon substrates in Streptomyces thermovulgaris strain 127 in connection with the inductive biosynthesis of glucose isomerase].
PubMed: Removal of contaminating proteinases from crude preparations of microbial enzymes.
PubMed: [Variability of Streptomyces griseoflavus strain 1339--producer of the enzyme glucose isomerase--following gamma ray exposure].
PubMed: [Properties of glucose isomerase from Streptomyces robeus S-606].
PubMed: An investigation of the equilibria between aqueous ribose, ribulose, and arabinose.
PubMed: [Effect of metal ions on the glucose isomerase activity of Streptomyces robeus S-606].
PubMed: [Effect of vitamins and various amino acids on glucose isomerase biosynthesis by Streptomyces albogriseolus culture].
PubMed: Selective isolation of acidophilic streptomyces strains for glucose isomerase production.
PubMed: X-ray crystal structure of D-xylose isomerase at 4-A resolution.
PubMed: [Optimization of the conditions for D-glucose isomerization to D-fructose with the glucose isomerase from Streptomyces atroolivaceus strain 700].
PubMed: [Natural dissociation in Streptomyces griseoflavus 1339, producer of the enzyme glucose isomerase].
PubMed: [Production of glucose isomerase by Streptomyces phaeochromogenes].
PubMed: [Biosynthesis of glucose isomerase in strains of the genus Streptomyces].
PubMed: Production of glucose isomerase by genus Streptomyces.
PubMed: [Effect of metal ions on the biosynthesis of the enzyme glucose isomerase by 2 Streptomyces sp strains].
PubMed: [Effect of carbon and nitrogen sources on the biosynthesis of the enzyme glucose isomerase by Streptomyces sp].
PubMed: [Comparative study of methods for isolating glucose isomerase from Streptomyces albogriseolus mycelium].
PubMed: [Role of metal ions in D-glucose and D-fructose isomerization by a glucose isomerase produced by 2 strains of streptomyces sp].
PubMed: [Effect of the pH and temperature in the isomerization process on the enzyme glucose isomerase produced by 2 Streptomyces sp. strains].
PubMed: [Selection of prospective Streptomyces genus strains producing the enzyme glucose isomerase].
PubMed: Studies on the combined action of amylases and glucose isomerase on starch and its hydrolyzate. Part I. Production, extraction, purification and kinetic behavior of glucose isomerase.
PubMed: Purification, Immobilization, and Some Properties of Glucose Isomerase from Streptomyces flavogriseus.
PubMed: Extraction of glucose isomerase from Streptomyces flavogriseus.
PubMed: Production of Glucose Isomerase by Streptomyces flavogriseus.
PubMed: Immobilization of Glucose Isomerase-Containing Streptomyces phaeochromogenes Cells in Fine-Particle Form.
PubMed: D-Lyxose as a substrate for Streptomyces D-xylose isomerase.
PubMed: Modeling the role of cyclic AMP in catabolite repression of inducible enzyme biosynthesis in microbial cells.
PubMed: [Glucose-isomerizing enzyme from Actinomyces olivocinereus and its immobilization on aminosilochrome].
PubMed: [Glucose isomerase activity in actinomycetes].
PubMed: Production of glucose-isomerase by Streptomyces fradiae.
PubMed: Studies on glucose isomerase from a Streptomyces species.
PubMed: Proton magnetic relaxation studies of the interaction of D-xylose and xylitol with D-xylose isomerase. Characterization of metal-enzyme-substrate interactions.
PubMed: D-Glucose isomerase: constitutive and catabolite repression-resistant mutants of Streptomyces phaeochromogenes.
PubMed: Subunit structure and amino acid composition of xylose isomerase from Streptomyces albus.
PubMed: An immobilized glucose isomerase for the continuous conversion of glucose to fructose.
PubMed: Properties of D-xylose isomerase from Streptomyces albus.
PubMed: Crystallographic studies of D-xylose isomerase.
PubMed: Properties of free and immobilized glucose isomerase.
PubMed: Kinetic and magnetic resonance studies of the mechanism of D-xylose isomerase. I. Binary and ternary complexes with manganese(II), substrates, and inhibitors.
PubMed: Free and immobilized glucose isomerase from Streptomyces phaeochromogenes.
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