calcium polyphosphate
calcium salts of polyphosphoric acids
 
Notes:
None found
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Category: emulsifiers, moisture-retaining agents, sequestrants, texturizers, acidity regulators
 
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JECFA Food Additive: Calcium Polyphosphate
GSFA Codex: Calcium polyphosphate (452(iv))
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Physical Properties:
Appearance: white crystalline powder (est)
Assay: 50.00 to 100.00 % 
Food Chemicals Codex Listed: No
Soluble in:
 acid medium
Insoluble in:
 water
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Organoleptic Properties:
Odor Description:
at 100.00 %. 
odorless
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: emulsifiers, moisture-retaining agents, sequestrants, texturizers, acidity regulators
Recommendation for calcium polyphosphate usage levels up to:
 not for fragrance use.
 
Recommendation for calcium polyphosphate flavor usage levels up to:
 not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
Assessment of one published review on health risks associated with phosphate additives in food
View page or View pdf
Re-evaluation of phosphoric acid–phosphates – di-, tri- and polyphosphates (E 338–341, E 343, E 450–452) as food additives and the safety of proposed extension of use
View page or View pdf
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References:
None found
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Other Information:
FDA Listing of Food Additive Status: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 calcium salts of polyphosphoric acids
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Articles:
PubMed: Co-culture of peripheral blood-derived mesenchymal stem cells and endothelial progenitor cells on strontium-doped calcium polyphosphate scaffolds to generate vascularized engineered bone.
PubMed: The inhibitory effect of strontium-doped calcium polyphosphate particles on cytokines from macrophages and osteoblasts leading to aseptic loosening in vitro.
PubMed: Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model.
PubMed: A review of phosphate mineral nucleation in biology and geobiology.
PubMed: Supplementation with platelet-rich plasma improves the in vitro formation of tissue-engineered cartilage with enhanced mechanical properties.
PubMed: Porous calcium polyphosphate bone substitutes: additive manufacturing versus conventional gravity sinter processing-effect on structure and mechanical properties.
PubMed: Solid freeform fabrication of porous calcium polyphosphate structures for bone substitute applications: in vivo studies.
PubMed: Application of strontium-doped calcium polyphosphate scaffold on angiogenesis for bone tissue engineering.
PubMed: Cell-mediated degradation of strontium-doped calcium polyphosphate scaffold for bone tissue engineering.
PubMed: Porous calcium polyphosphate as load-bearing bone substitutes: in vivo study.
PubMed: Degradation and drug release in calcium polyphosphate bioceramics: an MRI-based characterization.
PubMed: In vitro and in vivo study of calcium polyphosphate fiber/calcium phosphate cement/micromorselized bone composite for bone defect repair.
PubMed: Application of K/Sr co-doped calcium polyphosphate bioceramic as scaffolds for bone substitutes.
PubMed: The incorporation of a zone of calcified cartilage improves the interfacial shear strength between in vitro-formed cartilage and the underlying substrate.
PubMed: In vivo evaluation of calcium polyphosphate for bone regeneration.
PubMed: A novel alkali metals/strontium co-substituted calcium polyphosphate scaffolds in bone tissue engineering.
PubMed: A novel strontium-doped calcium polyphosphate/erythromycin/poly(vinyl alcohol) composite for bone tissue engineering.
PubMed: Membrane culture of bone marrow stromal cells yields better tissue than pellet culture for engineering cartilage-bone substitute biphasic constructs in a two-step process.
PubMed: In vitro study in stimulating the secretion of angiogenic growth factors of strontium-doped calcium polyphosphate for bone tissue engineering.
PubMed: Mechanical characteristics of solid-freeform-fabricated porous calcium polyphosphate structures with oriented stacked layers.
PubMed: [Preparation and properties of calcium polyphosphate-based composite scaffold for bone tissue engineering].
PubMed: Fabrication of a biodegradable calcium polyphosphate/polyvinyl-urethane carbonate composite for high load bearing osteosynthesis applications.
PubMed: Effect of bone graft substitute on marrow stromal cell proliferation and differentiation.
PubMed: Calcification of cartilage formed in vitro on calcium polyphosphate bone substitutes is regulated by inorganic polyphosphate.
PubMed: Solid freeform fabrication and characterization of porous calcium polyphosphate structures for tissue engineering purposes.
PubMed: Articular cartilage subpopulations respond differently to cyclic compression in vitro.
PubMed: Control of vertebrate skeletal mineralization by polyphosphates.
PubMed: In vivo study of porous strontium-doped calcium polyphosphate scaffolds for bone substitute applications.
PubMed: The study on the degradation and mineralization mechanism of ion-doped calcium polyphosphate in vitro.
PubMed: AP-1 DNA binding activity regulates the cartilage tissue remodeling process following cyclic compression in vitro.
PubMed: [Preparation of chitosan-encapsulated porous calcium polyphosphate bioceramic].
PubMed: In vitro study on the influence of strontium-doped calcium polyphosphate on the angiogenesis-related behaviors of HUVECs.
PubMed: Compaction strategies for modifying the drug delivery capabilities of gelled calcium polyphosphate matrices.
PubMed: Measurement of fluid ingress into calcium polyphosphate bioceramics using nuclear magnetic resonance microscopy.
PubMed: Characterization of short-chain poly3-hydroxybutyrate in baker's yeast.
PubMed: [Effect of processing parameters on the degradation of calcium polyphosphate bioceramic for bone tissue scaffolds].
PubMed: Effect of polymerization degree of calcium polyphosphate on its microstructure and in vitro degradation performance.
PubMed: Formation of biphasic constructs containing cartilage with a calcified zone interface.
PubMed: Osteochondral defect repair using a novel tissue engineering approach: sheep model study.
PubMed: Low-power laser stimulation of tissue engineered cartilage tissue formed on a porous calcium polyphosphate scaffold.
PubMed: [Structure and performance of calcium polyphosphate for bone tissue engineering].
PubMed: Gelled calcium polyphosphate matrices delay antibiotic release.
PubMed: Biodegradable porous calcium polyphosphate scaffolds for the three-dimensional culture of dental pulp cells.
PubMed: Repair of osteochondral defects with biphasic cartilage-calcium polyphosphate constructs in a sheep model.
PubMed: A high-conductance mode of a poly-3-hydroxybutyrate/calcium/polyphosphate channel isolated from competent Escherichia coli cells.
PubMed: Effect of strontium ions on the growth of ROS17/2.8 cells on porous calcium polyphosphate scaffolds.
PubMed: Formation of a nucleus pulposus-cartilage endplate construct in vitro.
PubMed: Isolation and structure determination of complexed poly(3-hydroxyalkanoate) from beet (Beta vulgaris L.).
PubMed: Vancomycin release behaviour from amorphous calcium polyphosphate matrices intended for osteomyelitis treatment.
PubMed: [Advances in research on calcium polyphosphate bioceramic for bone tissue engineering scaffold].
PubMed: Influence of anionic monomer content on the biodegradation and toxicity of polyvinyl-urethane carbonate-ceramic interpenetrating phase composites.
PubMed: Spectroscopic investigation of a new hybrid glass formed by the interaction between croconate ion and calcium polyphosphate.
PubMed: The effect of processing on the structural characteristics of vancomycin-loaded amorphous calcium phosphate matrices.
PubMed: A large, voltage-dependent channel, isolated from mitochondria by water-free chloroform extraction.
PubMed: [Structure characterization of calcium polyphosphate bioceramics during sintering process].
PubMed: Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage.
PubMed: Three-dimensional matrices of calcium polyphosphates support bone growth in vitro and in vivo.
PubMed: Tissue engineered nucleus pulposus tissue formed on a porous calcium polyphosphate substrate.
PubMed: [Repair of upper tibial epiphyseal defect with engineered epiphyseal cartilage in rabbits].
PubMed: Chondrocyte interactions with porous titanium alloy and calcium polyphosphate substrates.
PubMed: Synthesis and characterization of a novel polymer-ceramic system for biodegradable composite applications.
PubMed: [Experiment of histocompatibility and degradation in vivo of artificial material calcium polyphosphate fiber].
PubMed: [Feasibility of calcium polyphosphate fiber as scaffold materials for tendon tissue engineering in vitro].
PubMed: Characterization of cartilagenous tissue formed on calcium polyphosphate substrates in vitro.
PubMed: Attachment, spreading, and matrix formation by human gingival fibroblasts on porous-structured titanium alloy and calcium polyphosphate substrates.
PubMed: Porous calcium polyphosphate scaffolds for bone substitute applications in vivo studies.
PubMed: Fabrication of porous calcium polyphosphate implants by solid freeform fabrication: a study of processing parameters and in vitro degradation characteristics.
PubMed: Porous calcium polyphosphate scaffolds for bone substitute applications -- in vitro characterization.
PubMed: Detection, synthesis, structure, and function of oligo(3-hydroxyalkanoates): contributions by synthetic organic chemists.
PubMed: Proof for a nonproteinaceous calcium-selective channel in Escherichia coli by total synthesis from (R)-3-hydroxybutanoic acid and inorganic polyphosphate.
PubMed: Poly(3-hydroxybutyrate) is associated with specific proteins in the cytoplasm and membranes of Escherichia coli.
PubMed: Poly-3-hydroxybutyrate/polyphosphate complexes form voltage-activated Ca2+ channels in the plasma membranes of Escherichia coli.
PubMed: Genetic competence in Escherichia coli requires poly-beta-hydroxybutyrate/calcium polyphosphate membrane complexes and certain divalent cations.
PubMed: Evaluation of new high-performance calcium polyphosphate bioceramics as bone graft materials.
PubMed: Poly-beta-hydroxybutyrate/calcium polyphosphate complexes in eukaryotic membranes.
PubMed: Putative structure and functions of a poly-beta-hydroxybutyrate/calcium polyphosphate channel in bacterial plasma membranes.
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