(S)-(-)-perillyl alcohol, 18457-55-1

Articles:

PubMed:	Synthesis and antiproliferative effects of amino-modified perillyl alcohol derivatives.
PubMed:	A novel temozolomide-perillyl alcohol conjugate exhibits superior activity against breast cancer cells in vitro and intracranial triple-negative tumor growth in vivo.
PubMed:	Long-term outcome in patients with recurrent malignant glioma treated with Perillyl alcohol inhalation.
PubMed:	Perillyl alcohol suppresses antigen-induced immune responses in the lung.
PubMed:	Chemical composition and mosquito repellency of essential oil of Conyza newii propagated in different geographical locations of Kenya.
PubMed:	Intranasal administration of perillyl alcohol activates peripheral and bronchus-associated immune system in vivo.
PubMed:	Chemoprevention gene therapy (CGT) of pancreatic cancer using perillyl alcohol and a novel chimeric serotype cancer terminator virus.
PubMed:	Skin repair properties of d-Limonene and perillyl alcohol in murine models.
PubMed:	Anti-stress effects of d-limonene and its metabolite perillyl alcohol.
PubMed:	Influence of GSTM1 and GSTT1 polymorphisms on the survival rate of patients with malignant glioma under perillyl alcohol-based therapy.
PubMed:	Metabolic engineering of Escherichia coli for limonene and perillyl alcohol production.
PubMed:	Perillyl alcohol as a protective modulator against rat hepatocarcinogenesis via amelioration of oxidative damage and cell proliferation.
PubMed:	Double reduction of cyclic aromatic sulfonamides: synthesis of (+)-mesembrine and (+)-mesembranol.
PubMed:	Whole-cell-based CYP153A6-catalyzed (S)-limonene hydroxylation efficiency depends on host background and profits from monoterpene uptake via AlkL.
PubMed:	Perillyl alcohol causes G1 arrest through p15(INK4b) and p21(WAF1/Cip1) induction.
PubMed:	Perillyl alcohol for the treatment of temozolomide-resistant gliomas.
PubMed:	The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells.
PubMed:	Growth-inhibiting effects of Paeonia lactiflora root steam distillate constituents and structurally related compounds on human intestinal bacteria.
PubMed:	Analysis of EGF+61A>G polymorphism and EGF serum levels in Brazilian glioma patients treated with perillyl alcohol-based therapy.
PubMed:	Microbial hydroxylation of S-(-)-perillyl alcohol by Fusarium heterosporium.
PubMed:	Calcium blockers decrease the bortezomib resistance in mantle cell lymphoma via manipulation of tissue transglutaminase activities.
PubMed:	Anticancer efficacy of perillyl alcohol-bearing PLGA microparticles.
PubMed:	Influence of the active compounds of Perilla frutescens leaves on lipid membranes.
PubMed:	An efficient route to selective bio-oxidation catalysts: an iterative approach comprising modeling, diversification, and screening, based on CYP102A1.
PubMed:	Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C-H-oxyfunctionalization.
PubMed:	Evaluation of the antioxidant and antiproliferative potential of bioflavors.
PubMed:	Perillyl alcohol protects against ethanol induced acute liver injury in Wistar rats by inhibiting oxidative stress, NFκ-B activation and proinflammatory cytokine production.
PubMed:	Chemo-resistant protein expression pattern of glioblastoma cells (A172) to perillyl alcohol.
PubMed:	The anticancer drug perillyl alcohol is a Na/K-ATPase inhibitor.
PubMed:	Efficacy of monoterpene perillyl alcohol upon survival rate of patients with recurrent glioblastoma.
PubMed:	Dynamic proteomic overview of glioblastoma cells (A172) exposed to perillyl alcohol.
PubMed:	(1S,2R,4S)-1-[(Benzyl-amino)-meth-yl]-4-(prop-1-en-2-yl)cyclo-hexane-1,2-diol.
PubMed:	Protective effects of mastic oil from Pistacia lentiscus variation chia against experimental growth of lewis lung carcinoma.
PubMed:	Perillyl alcohol and methyl jasmonate sensitize cancer cells to cisplatin.
PubMed:	Tricistronic overexpression of cytochrome P450cam, putidaredoxin, and putidaredoxin reductase provides a useful cell-based catalytic system.
PubMed:	Components of lemon essential oil attenuate dementia induced by scopolamine.
PubMed:	Anti-thrombin as a prognostic biomarker candidate for patients with recurrent glioblastoma multiform under treatment with perillyl alcohol.
PubMed:	Perillyl alcohol attenuates Ras-ERK signaling to inhibit murine skin inflammation and tumorigenesis.
PubMed:	Mechanism of in vitro pancreatic cancer cell growth inhibition by melanoma differentiation-associated gene-7/interleukin-24 and perillyl alcohol.
PubMed:	Chemoprevention by perillyl alcohol coupled with viral gene therapy reduces pancreatic cancer pathogenesis.
PubMed:	Fragrance material review on p-mentha-1,8-dien-7-ol.
PubMed:	Synthesis of phosphatidylated-monoterpene alcohols catalyzed by phospholipase D and their antiproliferative effects on human cancer cells.
PubMed:	Preliminary results from a phase I/II study of perillyl alcohol intranasal administration in adults with recurrent malignant gliomas.
PubMed:	Perillyl alcohol and perillic acid induced cell cycle arrest and apoptosis in non small cell lung cancer cells.
PubMed:	Anaplastic oligodendroglioma responding favorably to intranasal delivery of perillyl alcohol: a case report and literature review.
PubMed:	Cell cycle arrest by the isoprenoids perillyl alcohol, geraniol, and farnesol is mediated by p21(Cip1) and p27(Kip1) in human pancreatic adenocarcinoma cells.
PubMed:	Effects of perillyl alcohol and heat shock treatment in gene expression of human lung adenocarcinoma cell line A549.
PubMed:	Mastic oil from Pistacia lentiscus var. chia inhibits growth and survival of human K562 leukemia cells and attenuates angiogenesis.
PubMed:	Perillyl alcohol induces c-Myc-dependent apoptosis in Bcr/Abl-transformed leukemia cells.
PubMed:	Polycyclic aromatic hydrocarbon-induced CYP1B1 activity is suppressed by perillyl alcohol in MCF-7 cells.
PubMed:	Perillyl alcohol inhibits a calcium-dependent constitutive nuclear factor-kappaB pathway.
PubMed:	Perillyl alcohol inhibits the expression and function of the androgen receptor in human prostate cancer cells.
PubMed:	Protein and m-RNA expression of farnesyl-transferases, RhoA and RhoB in rat liver hepatocytes: action of perillyl alcohol and vitamin A in vivo.
PubMed:	CaaX-prenyltransferases are essential for expression of genes involvedin the early stages of monoterpenoid biosynthetic pathway in Catharanthus roseus cells.
PubMed:	Biocatalytic production of perillyl alcohol from limonene by using a novel Mycobacterium sp. cytochrome P450 alkane hydroxylase expressed in Pseudomonas putida.
PubMed:	Perillyl alcohol induces apoptosis in human glioblastoma multiforme cells.
PubMed:	Effect of D-limonene on immune response in BALB/c mice with lymphoma.
PubMed:	An HPLC method for quantitation of perillyl alcohol in a topical pharmaceutical cream formulation.
PubMed:	A pilot surrogate end point biomarker trial of perillyl alcohol in breast neoplasia.
PubMed:	R-(+)-perillyl alcohol-induced cell cycle changes, altered actin cytoskeleton, and decreased ras and p34(cdc2) expression in colonic adenocarcinoma SW480 cells.
PubMed:	Monoterpenes enhanced the sensitivity of head and neck cancer cells to radiation treatment in vitro.
PubMed:	Perillyl alcohol is an angiogenesis inhibitor.
PubMed:	A phase I trial of perillyl alcohol administered four times daily for 14 days out of 28 days.
PubMed:	Perillyl alcohol inhibits human breast cancer cell growth in vitro and in vivo.
PubMed:	Perillyl alcohol-mediated inhibition of lung cancer cell line proliferation: potential mechanisms for its chemotherapeutic effects.
PubMed:	Development of a perillyl alcohol topical cream formulation.
PubMed:	Effect of antiproliferative agents on vascular function in normal and in vitro balloon-injured porcine coronary arteries.
PubMed:	Phase II trial of perillyl alcohol (NSC 641066) administered daily in patients with metastatic androgen independent prostate cancer.
PubMed:	Anti-leukemia effect of perillyl alcohol in Bcr/Abl-transformed cells indirectly inhibits signaling through Mek in a Ras- and Raf-independent fashion.
PubMed:	Cytotoxicity of perillyl alcohol against cancer cells is potentiated by hyperthermia.
PubMed:	Perillyl alcohol and perillaldehyde induced cell cycle arrest and cell death in BroTo and A549 cells cultured in vitro.
PubMed:	Phase I trial of perillyl alcohol administered four times daily continuously.
PubMed:	Perillyl alcohol mediated radiosensitization via augmentation of the Fas pathway in prostate cancer cells.
PubMed:	Perillyl alcohol as a radio-/chemosensitizer in malignant glioma.
PubMed:	Phase II trial of perillyl alcohol in patients with metastatic colorectal cancer.
PubMed:	Perillyl alcohol as a chemopreventive agent in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.
PubMed:	A phase I trial of perillyl alcohol in patients with advanced solid tumors.
PubMed:	Monoterpene regulation of Ras and Ras-related protein expression.
PubMed:	Effects of the isoprenoids perillyl alcohol and farnesol on apoptosis biomarkers in pancreatic cancer chemoprevention.
PubMed:	Effects of perillyl alcohol in glial C6 cell line in vitro and anti-metastatic activity in chorioallantoic membrane model.
PubMed:	Monoterpenes inhibit proliferation of human colon cancer cells by modulating cell cycle-related protein expression.
PubMed:	Phase I study of perillyl alcohol in patients with refractory malignancies.
PubMed:	A phase II trial of daily perillyl alcohol in patients with advanced ovarian cancer: Eastern Cooperative Oncology Group Study E2E96.
PubMed:	Effects of perillyl alcohol on melanoma in the TPras mouse model.
PubMed:	Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes.
PubMed:	Antileukemia activity of perillyl alcohol (POH): uncoupling apoptosis from G0/G1 arrest suggests that the primary effect of POH on Bcr/Abl-transformed cells is to induce growth arrest.
PubMed:	Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes.
PubMed:	Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol.
PubMed:	Chemopreventive efficacy of promising farnesyltransferase inhibitors.
PubMed:	Failure to demonstrate chemoprevention by the monoterpene perillyl alcohol during early rat hepatocarcinogenesis: a cautionary note.
PubMed:	Phase I pharmacokinetic trial of perillyl alcohol (NSC 641066) in patients with refractory solid malignancies.
PubMed:	Cytotoxicity and biotransformation of the anticancer drug perillyl alcohol in PC12 cells and in the rat.
PubMed:	Perillyl alcohol inhibits TCR-mediated [Ca(2+)](i) signaling, alters cell shape and motility, and induces apoptosis in T lymphocytes.
PubMed:	Phase I clinical and pharmacokinetic study of perillyl alcohol administered four times a day.
PubMed:	Perillyl alcohol, an inhibitor of geranylgeranyl transferase, induces apoptosis of immortalized human vascular smooth muscle cells in vitro.
PubMed:	Drug development in prostate cancer.
PubMed:	Perillyl alcohol selectively induces G0/G1 arrest and apoptosis in Bcr/Abl-transformed myeloid cell lines.
PubMed:	Induction of AP-1 activity by perillyl alcohol in breast cancer cells.
PubMed:	Enhancement of sterol synthesis by the monoterpene perillyl alcohol is unaffected by competitive 3-hydroxy-3-methylglutaryl-CoA reductase inhibition.
PubMed:	Gas chromatographic-mass spectrometric analysis of perillyl alcohol and metabolites in plasma.
PubMed:	Activation of the transforming growth factor beta signaling pathway and induction of cytostasis and apoptosis in mammary carcinomas treated with the anticancer agent perillyl alcohol.
PubMed:	Monoterpenes inhibit cell growth, cell cycle progression, and cyclin D1 gene expression in human breast cancer cell lines.
PubMed:	Effects of the antitumor agent perillyl alcohol on H-Ras vs. K-Ras farnesylation and signal transduction in pancreatic cells.
PubMed:	Phase I clinical trial of perillyl alcohol administered daily.
PubMed:	Inhibitory effects of perillyl alcohol on UVB-induced murine skin cancer and AP-1 transactivation.
PubMed:	Quantification of carvone, cineole, perillaldehyde, perillyl alcohol and sobrerol by isocratic high-performance liquid chromatography.
PubMed:	Induction of the apoptosis-promoting protein Bak by perillyl alcohol in pancreatic ductal adenocarcinoma relative to untransformed ductal epithelial cells.
PubMed:	Inhibition of type I and type II geranylgeranyl-protein transferases by the monoterpene perillyl alcohol in NIH3T3 cells.
PubMed:	Total Synthesis of the Enantiomer of the Furanocembrane Rubifolide.
PubMed:	Oral monoterpene therapy (perillyl alcohol) reduces vein graft intimal hyperplasia.
PubMed:	Inhibition of pancreatic cancer growth by the dietary isoprenoids farnesol and geraniol.
PubMed:	Chemoprevention of colon carcinogenesis by dietary perillyl alcohol.
PubMed:	Chemopreventive effect of perillyl alcohol on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induced tumorigenesis in (C3H/HeJ X A/J)F1 mouse lung.
PubMed:	Inhibition of tumor cell growth by monoterpenes in vitro: evidence of a Ras-independent mechanism of action.
PubMed:	Effects of monoterpenes and mevinolin on murine colon tumor CT-26 in vitro and its hepatic "metastases" in vivo.
PubMed:	Chemotherapy of pancreatic cancer with the monoterpene perillyl alcohol.
PubMed:	Induction of differentiation in neuro-2A cells by the monoterpene perillyl alcohol.
PubMed:	Differential effects of monoterpenes and lovastatin on RAS processing.
PubMed:	Pharmacokinetics of active drug metabolites after oral administration of perillyl alcohol, an investigational antineoplastic agent, to the dog.
PubMed:	Isoprenylation of proteins in the protozoan Giardia lamblia.
PubMed:	The inhibition of protein prenyltransferases by oxygenated metabolites of limonene and perillyl alcohol.
PubMed:	Induction of apoptosis in liver tumors by the monoterpene perillyl alcohol.
PubMed:	Inhibition of ubiquinone and cholesterol synthesis by the monoterpene perillyl alcohol.
PubMed:	Mammary carcinoma regression induced by perillyl alcohol, a hydroxylated analog of limonene.