alpha-damascenone
1-(2,6,6-trimethylcyclohexa-2,4-dienyl)but-2-en-1-one
 
Notes:
None found
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CAS Number: 35044-63-4 
FDA UNII: 2885IA3NW1
Molecular Weight: 190.28566000
Formula: C13 H18 O
Category: flavor and fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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DG SANTE Food Flavourings: 07.231  alpha-damascenone
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Specific Gravity: 1.01500 to 1.02100 @  25.00 °C.
Pounds per Gallon - (est).: 8.446 to  8.496
Refractive Index: 1.50200 to 1.50800 @  20.00 °C.
Soluble in:
 alcohol
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: flavor and fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
IFRA Critical Effect: Sensitization
IFRA fragrance material specification:
 Should not be used as fragrance ingredients such that the total level in finished cosmetic products exceeds 0.02%, individually or in combination. Based on test data showing sensitising potential for these materials and on evidence of cross-reactivity. (IFRA guidelines)
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 0.07 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 2979.42 (μg/person/day)
Structure Class: I
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 9.8100025.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): 15.0000020.00000
Edible ices, including sherbet and sorbet (03.0): 1.750003.00000
Processed fruit (04.1): 0.030001.00000
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): 8.3000025.00000
Confectionery (05.0): 14.0000040.00000
Chewing gum (05.0): --
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): 9.0000025.00000
Bakery wares (07.0): 9.9800030.00000
Meat and meat products, including poultry and game (08.0): 1.0000010.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): --
Eggs and egg products (10.0): 5.000005.00000
Sweeteners, including honey (11.0): 2.500002.50000
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 0.630005.00000
Foodstuffs intended for particular nutritional uses (13.0): 1.250002.00000
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): 2.030005.05000
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 1.800004.00000
Ready-to-eat savouries (15.0): 1.000001.50000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): --
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Safety References:
European Food Safety Athority(EFSA): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 210: alpha,beta-Unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19[1]
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 210 Revision 2 (FGE.210Rev2): Consideration of genotoxic potential for a,ß-unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19
View page or View pdf
Scientific Opinion on Flavouring Group Evaluation 210 Revision 3 (FGE.210Rev3): Consideration of genotoxic potential for a,ß-unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19
View page or View pdf
AIDS Citations: Search
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Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0035044634
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References:
Pubchem (cas): 35044-63-4
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Other Information:
HMDB (The Human Metabolome Database): Search
VCF-Online: VCF Volatile Compounds in Food
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 mindium laevigatum
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Synonyms:
1-(2,6,6-trimethyl cyclohexa-2,4-dienyl) but-2-en-1-one
1-(2,6,6-trimethylcyclohexa-2,4-dienyl)but-2-en-1-one
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