Articles:
(2R-(2alpha,3beta(R*),4(E(R*))))-3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethyl) 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofura
Notes:
isolated from salvia miltiorrhiza.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 115939-25-8 Salvianolicacid B >98% Salvianolic acid A is extracted from the root of Salvia miltiorrhiza Bge.
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| CAS Number: | 115939-25-8 |  3D/inchi
|
| Other(deleted CASRN): | 115939-25-8 | |
| FDA UNII: | C1GQ844199 | |
| XlogP3-AA: | 4.00 (est) | |
| Molecular Weight: | 718.62230000 | |
| Formula: | C36 H30 O16 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | yellow-brown powder (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 1020.27 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 612.00 °F. TCC ( 322.10 °C. ) (est) |
| logP (o/w): | 2.140 (est) |
| Soluble in: | |
| water, 1.04 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Salvianolicacid B >98%
Odor: characteristic Use: Salvianolic acid A is extracted from the root of Salvia miltiorrhiza Bge. |
| Coompo |
| For experimental / research use only. |
| Salvianolic Acid B from Plants ≥96%
Odor: characteristic Use: Salvianolic acid B showed a protective action against the ischemia-reperfusion induced injury in rat brain by reducing lipid peroxides, scavenging free radicals and improving the energy metabolism.
In cerebral ischemia rats, Sal B reduced learning and memory dysfunctions induced by ischemia. Moreover, salvianolic acids, including Sal B, were shown to improve regional cerebral blood flow in the ischemic hemisphere and inhibit platelet aggregation in rats. More recently, Sal B was reported to be capable of improving the recovery of motor function after cerebral ischemia in rats. However, the mechanism responsible for such protective effects remains largely unknown. It has been considered that cerebral endothelium apoptosis caused by reactive oxygen species including hydrogen peroxide (H2O2) is implicated in the pathogenesis of cerebrovascular disorders.
It was shown to inhibit apoptosis in many cell types, also inhibits apoptosis that is induced by the death receptor in the HL-7702 hepatocyte cell line. Sal B can effectively inhibit hepatocyte apoptosis as well as the underlying mechanisms related to regulating mediators in death receptor and mitochondrial pathways. |
| ExtraSynthese |
| For experimental / research use only. |
| Salvianolic Acid B (HPLC) ≥95% |
| Qingdao Dacon Trading |
| Salvianolic acid B+Tanshinone IIA |
Safety Information:
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | natural substances and extractives | ||
| Recommendation for salvianolic acid B usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for salvianolic acid B flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 13991587 |
| National Institute of Allergy and Infectious Diseases: | Data |
| Chemidplus: | 0115939258 |
References:
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 13991587 |
| Pubchem (sid): | 135120056 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| sage red sage Search Trop Picture |
Synonyms:
| (2R-(2alpha,3beta(R*),4(E(R*))))-3-(1- | carboxy-2-(3,4-dihydroxyphenyl)ethyl) 4-(3-(1-carboxy-2-(3,4-dihydroxyphenyl)ethoxy)-3-oxo-1-propenyl)-2-(3,4-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-3-benzofura |
| salvianolicacid B |