Articles:
Notes:
Very widespread in the plant world, e.g. in Brassicaceae, Apocynaceae, Dilleniaceae, Ranunculaceae, Leguminosae, etc. Found esp. in broccoli, capers, chives, kale, garden cress, fennel, lovage, dill weed and tarragon [CCD]
Kaempferol is a natural flavonol, a type of flavonoid. Many glycosides of kaempferol, such as kaempferitrin and astragalin, have been isolated as natural products from plants. Kaempferol consumption in tea and broccoli has been associated with reduced risk of heart disease. [Wikipedia]
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 520-18-3 Kaempferol >98% Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources.
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Glentham Life Sciences Ltd The Chemical, Biochemical & Research Essentials Supplier Glentham Life Sciences is a supplier of fine chemicals and raw materials with warehousing, laboratories and packaging facilities in the UK. With a Glentham Life Sciences account you can view more product details, request quotes and order products online. Email: Info Email: Sales Email: Tech Support Voice: +44 (0) 1225 667798 Fax: +44 (0) 2033 978909 Facebook Twitter Linkedin Google+ News Distribution Products List: View Product(s): GP7425 Kaempferol
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| CAS Number: | 520-18-3 |  3D/inchi
|
| ECHA EINECS - REACH Pre-Reg: | 208-287-6 | |
| FDA UNII: | 731P2LE49E | |
| Nikkaji Web: | J1.575J | |
| Beilstein Number: | 0304401 | |
| MDL: | MFCD00016938 | |
| XlogP3: | 1.90 (est) | |
| Molecular Weight: | 286.23990000 | |
| Formula: | C15 H10 O6 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Appearance: | yellow needles (est) |
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Melting Point: | 277.00 °C. @ 760.00 mm Hg |
| Boiling Point: | 582.00 to 583.00 °C. @ 860.00 mm Hg (est) |
| Flash Point: | 439.00 °F. TCC ( 226.10 °C. ) (est) |
| logP (o/w): | 2.685 (est) |
| Soluble in: | |
| alcohol | |
| water, 1191 mg/L @ 25 °C (est) | |
| Insoluble in: | |
| water | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| CosIng: | cosmetic data |
| Cosmetic Uses: |
antioxidants skin conditioning - emollient |
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Kaempferol 98% |
| BOC Sciences |
| For experimental / research use only. |
| Kaempferol >98%
Odor: characteristic Use: Kaempferol is a natural flavonol, a type of flavonoid, that has been isolated from plant sources. |
| Changzhou Longo Chemical |
| Kempferol |
| Coompo |
| For experimental / research use only. |
| Kempferol from Plants ≥96%
Odor: characteristic Use: Kaempferol have a wide range of pharmacological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, cardioprotective, neuroprotective, antidiabetic, antiosteoporotic, estrogenic/antiestrogenic, anxiolytic, analgesic, and antiallergic activities.
Keampferol is a strong antioxidant and helps to prevent oxidative damage of our cells, lipids and DNA. Kaempferol seems to prevent arteriosclerosis by inhibiting the oxidation of low density lipoprotein and the formation of platelets in the blood. Studies have also confirmed that kaempferol acts as a chemopreventive agent, which means that it inhibits the formation of cancer cells.
Kaempferol inhibits monocyte chemoattractant protein (MCP-1). MCP-1 plays a role in the initial steps of atherosclerotic plaque formation. Kaempferol can help to fight cancer because it reduces the resistance of cancer cells to anti-cancer drugs such as vinbalstine and paclitaxel.
Kaempferol consumption is also correlated with a reduced lung cancer incidence. Kaempferol may be a potent prophylactic against NOX-mediated neurodegeneration. |
| ExtraSynthese |
| For experimental / research use only. |
| Kaempferol (HPLC) ≥90% |
| Glentham Life Sciences |
| Kaempferol |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Kempferol ≥98% |
| Shaanxi Y-Herb Biotechnology |
| CAS 520-18-3 Kaempferia Galanga Extract Kaempferol Powder 30% 50% 70% 90% 98% |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Kempferol ≥97.0% (HPLC) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | cosmetic agents | ||
| Recommendation for kempferol usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for kempferol flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| Carcinogenic Potency Database: | Search |
| EPA GENetic TOXicology: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 5280863 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one | |
| Chemidplus: | 0000520183 |
References:
| 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5280863 |
| Pubchem (sid): | 134976840 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| Golm Metabolome Database: | Search |
| KEGG (GenomeNet): | C05903 |
| HMDB (The Human Metabolome Database): | HMDB05801 |
| FooDB: | FDB000633 |
| YMDB (Yeast Metabolome Database): | YMDB01722 |
| MedlinePlusSupp: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
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Synonyms:
| campherol | |
| kaempferol | |
| nimbecetin | |
| pelargidenolon | |
| populnetin | |
| rhamnolutein | |
| robigenin | |
| swartziol | |
| 3,4',5,7- | tetrahydroxyflavone |
| trifolitin | |
| 3,5,7- | trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| 3,5,7- | trihydroxy-2-(4-hydroxyphenyl)chromen-4-one |