tellimagrandin I
D-glucose, cyclic 4,6-[(1S)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 2,3-bis(3,4,5-trihydroxybenzoate)
 
Notes:
isolated from filipendula palmata.
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CAS Number: 79786-08-6Picture of molecule3D/inchi
XlogP3-AA: 0.90 (est)
Molecular Weight: 786.56362000
Formula: C34 H26 O22
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 1395.26 °C. @ 760.00 mm Hg (est)
Flash Point: 814.00 °F. TCC ( 434.30 °C. ) (est)
logP (o/w): 1.067 (est)
Soluble in:
 water, 9.791 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
Nacalai USA
For experimental / research use only.
Tellimagrandin I
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for tellimagrandin I usage levels up to:
 not for fragrance use.
 
Recommendation for tellimagrandin I flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 73179
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0079786086
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References:
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 73179
Pubchem (sid): 135030188
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
FooDB: FDB018804
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 clove leaf
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 clove plant
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 filipendula palmata
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 flax seed
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 guava leaf
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 guava pineapple guava
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 guava plant
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 pomegranate leaf
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 pomegranate pericarp
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 quercus spp.
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 rose hips
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Synonyms:
D-glucose, cyclic 4,6-(4,4',5,5',6,6'-hexahydroxy(1,1'-biphenyl)-2,2'-dicarboxylate) 2,3-bis(3,4,5-trihydroxybenzoate), (S)-
D-glucose, cyclic 4,6-[(1S)-4,4',5,5',6,6'-hexahydroxy[1,1'-biphenyl]-2,2'-dicarboxylate] 2,3-bis(3,4,5-trihydroxybenzoate)
 tellimagradin I
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Articles:
PubMed: Hydrolyzable tannins from hydroalcoholic extract from Poincianella pluviosa stem bark and its wound-healing properties: phytochemical investigations and influence on in vitro cell physiology of human keratinocytes and dermal fibroblasts.
PubMed: Cytotoxic effects of ellagitannins isolated from walnuts in human cancer cells.
PubMed: Rapid profiling of phenolic compounds of green and fermented Bergenia crassifolia L. leaves by UPLC-DAD-QqQ-MS and HPLC-DAD-ESI-QTOF-MS.
PubMed: Synthesis and biological profiling of tellimagrandin I and analogues reveals that the medium ring can significantly modulate biological activity.
PubMed: Synthesis of ellagitannin natural products.
PubMed: Tellimagrandin I, HCV invasion inhibitor from Rosae Rugosae Flos.
PubMed: Prooxidant action of chebulinic acid and tellimagrandin I: causing copper-dependent DNA strand breaks.
PubMed: Chebulinic acid and tellimagrandin I inhibit DNA strand breaks by hydroquinone/Cu(II) and H(2)O(2)/Cu(II), but potentiate DNA strand breaks by H(2)O(2)/Fe(II).
PubMed: Effect of polyphenol-rich extract from walnut on diet-induced hypertriglyceridemia in mice via enhancement of fatty acid oxidation in the liver.
PubMed: Walnut polyphenols prevent liver damage induced by carbon tetrachloride and d-galactosamine: hepatoprotective hydrolyzable tannins in the kernel pellicles of walnut.
PubMed: [Studies on hydrolysable tannin constituents in seed of Juglans regia(I)].
PubMed: Tellimagrandin I enhances gap junctional communication and attenuates the tumor phenotype of human cervical carcinoma HeLa cells in vitro.
PubMed: Effects of tannins and related polyphenols on methicillin-resistant Staphylococcus aureus.
PubMed: Syntheses of stereochemically diverse nine-membered ring-containing biaryls.
PubMed: Antibacterial activity of hydrolyzable tannins derived from medicinal plants against Helicobacter pylori.
PubMed: Inhibitory effect of tellimagrandin I on chemically induced differentiation of human leukemia K562 cells.
PubMed: Mechanisms of action of corilagin and tellimagrandin I that remarkably potentiate the activity of beta-lactams against methicillin-resistant Staphylococcus aureus.
PubMed: Polyphenolic allelochemicals from the aquatic angiosperm Myriophyllum spicatum inhibit photosystem II.
PubMed: Toxicity of tannins towards the free-living nematode Caenorhabditis elegans and the brine shrimp Artemia salina.
PubMed: Identification of hydrolysable tannins in the reaction zone of Eucalyptus nitens wood by high performance liquid chromatography--electrospray ionisation mass spectrometry.
PubMed: Isolation of virus-cell fusion inhibitory components from Eugenia caryophyllata.
PubMed: Hydrolyzable tannins and related polyphenols from Eucalyptus globulus.
PubMed: Chemistry and function of vegetable polyphenols with high molecular weights.
PubMed: Restoration of effectiveness of beta-lactams on methicillin-resistant Staphylococcus aureus by tellimagrandin I from rose red.
PubMed: [Chemical constituents of tannin in Filipendula palmata Pall].
PubMed: Carbonic anhydrase inhibitors from the pericarps of Punica granatum L.
PubMed: Antitumor activity and interleukin-1 induction by tannins.
PubMed: Tannins of cornaceous plants. I. Cornusiins A, B and C, dimeric monomeric and trimeric hydrolyzable tannins from Cornus officinalis, and orientation of valoneoyl group in related tannins.
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