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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 0.02371 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for alpha-eleostearic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for alpha-eleostearic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (9Z,11E,13E)- | octadeca-9,11,13-trienoic acid | | (9E,11Z,13E)-9,11,13- | octadecatrienoic acid | | (E,Z,E)-9,11,13- | octadecatrienoic acid | | 9,11,13- | octadecatrienoic acid, (9Z,11E,13E)- |
Articles:
| PubMed: | Compositional Analyses and Shelf-Life Modeling of Njangsa (Ricinodendron heudelotii) Seed Oil Using the Weibull Hazard Analysis. |
| PubMed: | α-Eleostearic acid-containing triglycerides for a continuous assay to determine lipase sn-1 and sn-3 regio-preference. |
| PubMed: | Roles of Peroxisome Proliferator-Activated Receptor α in Bitter Melon Seed Oil-Corrected Lipid Disorders and Conversion of α-Eleostearic Acid into Rumenic Acid in C57BL/6J Mice. |
| PubMed: | A conjugated fatty acid present at high levels in bitter melon seed favorably affects lipid metabolism in hepatocytes by increasing NAD(+)/NADH ratio and activating PPARα, AMPK and SIRT1 signaling pathway. |
| PubMed: | A continuous spectrophotometric assay that distinguishes between phospholipase A1 and A2 activities. |
| PubMed: | Impact of Cultivar on Profile and Concentration of Lipophilic Bioactive Compounds in Kernel Oils Recovered from Sweet Cherry (Prunus avium L.) by-Products. |
| PubMed: | Bitter melon: a panacea for inflammation and cancer. |
| PubMed: | New lipase assay using Pomegranate oil coating in microtiter plates. |
| PubMed: | Silphiperfolene-Type Terpenoids and Other Metabolites from Cultures of the Tropical Ascomycete Hypoxylon rickii (Xylariaceae). |
| PubMed: | Modulation of peroxisome proliferator-activated receptor gamma (PPAR γ) by conjugated fatty acid in obesity and inflammatory bowel disease. |
| PubMed: | miRNA expression in human intestinal Caco-2 cells is comparably regulated by cis- and trans-fatty acids. |
| PubMed: | Comparative real-time study of cellular uptake of a formulated conjugated linolenic acid rich nano and conventional macro emulsions and their bioactivity in ex vivo models for parenteral applications. |
| PubMed: | Development of a high-throughput assay for measuring phospholipase A activity using synthetic 1,2-α-eleostearoyl-sn-glycero-3-phosphocholine coated on microtiter plates. |
| PubMed: | Characterization of a soluble phosphatidic acid phosphatase in bitter melon (Momordica charantia). |
| PubMed: | Comparative prophylactic effects of α-eleostearic acid rich nano and conventional emulsions in induced diabetic rats. |
| PubMed: | Fatty acid profile and unigene-derived simple sequence repeat markers in tung tree (Vernicia fordii). |
| PubMed: | Conjugated linolenic acids and their bioactivities: a review. |
| PubMed: | Characterization of white Mahlab (Prunus mahaleb L.) seed oil: a rich source of α-eleostearic acid. |
| PubMed: | Α-eleostearic acid inhibits growth and induces apoptosis in breast cancer cells via HER2/HER3 signaling. |
| PubMed: | Expression analysis of VfDGAT2 in various tissues of the tung tree and in transgenic yeast. |
| PubMed: | Effects of α-eleostearic acid on asolectin liposomes dynamics: relevance to its antioxidant activity. |
| PubMed: | Development of a high-throughput assay for measuring lipase activity using natural triacylglycerols coated on microtiter plates. |
| PubMed: | Jacaric acid is rapidly metabolized to conjugated linoleic acid in rats. |
| PubMed: | Protective effect of conjugated linolenic acid isomers present in vegetable oils against arsenite-induced renal toxicity in rat model. |
| PubMed: | Identification of a Bioactive Compound against Adult T-cell Leukaemia from Bitter Gourd Seeds. |
| PubMed: | Synergistic effect of conjugated linolenic acid isomers against induced oxidative stress, inflammation and erythrocyte membrane disintegrity in rat model. |
| PubMed: | Prophylactic effect of α-linolenic acid and α-eleostearic acid against MeHg induced oxidative stress, DNA damage and structural changes in RBC membrane. |
| PubMed: | Conjugated fatty acid synthesis: residues 111 and 115 influence product partitioning of Momordica charantia conjugase. |
| PubMed: | Studies on comparative efficacy of α-linolenic acid and α-eleostearic acid on prevention of organic mercury-induced oxidative stress in kidney and liver of rat. |
| PubMed: | Antioxidant and anti-inflammatory effect of conjugated linolenic acid isomers against streptozotocin-induced diabetes. |
| PubMed: | An ultraviolet spectrophotometric assay for the screening of sn-2-specific lipases using 1,3-O-dioleoyl-2-O-α-eleostearoyl-sn-glycerol as substrate. |
| PubMed: | Dietary α-eleostearic acid ameliorates experimental inflammatory bowel disease in mice by activating peroxisome proliferator-activated receptor-γ. |
| PubMed: | Growth inhibition and apoptotic effect of alpha-eleostearic acid on human breast cancer cells. |
| PubMed: | Studies on the antioxygenic activity of bitter gourd (Momordica charantia) and its fractions using various in vitro models. |
| PubMed: | Recent advances in the analysis of the site-specific isotopic fractionation of metabolites such as fatty acids using anisotropic natural-abundance 2H NMR spectroscopy: application to conjugated linolenic methyl esters. |
| PubMed: | [Mineral elements analysis of Momordica charantiap seeds by ICP-AES and fatty acid profile identification of seed oil by GC-MS]. |
| PubMed: | Ameliorative role of conjugated linolenic acid isomers against oxidative DNA damage induced by sodium arsenite in rat model. |
| PubMed: | Poly(ADP-ribose) polymerase (PARP)-1-independent apoptosis-inducing factor (AIF) release and cell death are induced by eleostearic acid and blocked by alpha-tocopherol and MEK inhibition. |
| PubMed: | Pomegranate (Punica granatum) seed linolenic acid isomers: concentration-dependent modulation of estrogen receptor activity. |
| PubMed: | Alpha-eleostearic acid induces autophagy-dependent cell death through targeting AKT/mTOR and ERK1/2 signal together with the generation of reactive oxygen species. |
| PubMed: | Alpha-eleostearic acid suppresses proliferation of MCF-7 breast cancer cells via activation of PPARgamma and inhibition of ERK 1 / 2. |
| PubMed: | Ricinodendron heutelotii (Bail.) or Tetracarpidium conophorum Müll. oils fed to male rats lower blood lipids. |
| PubMed: | Comparative study of antioxidant activity of alpha-eleostearic acid and punicic acid against oxidative stress generated by sodium arsenite. |
| PubMed: | Steady-state and time-resolved fluorescence studies of stripped Borage oil. |
| PubMed: | Alpha-eleostearic acid and its dihydroxy derivative are major apoptosis-inducing components of bitter gourd. |
| PubMed: | Tumor angiogenesis suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via peroxisome proliferator-activated receptor gamma. |
| PubMed: | Antioxidative effect of conjugated linolenic acid in diabetic and non-diabetic blood: an in vitro study. |
| PubMed: | Re-characterization of three conjugated linolenic acid isomers by GC-MS and NMR. |
| PubMed: | Characteristic long-chain fatty acid of Pleurocybella porrigens. |
| PubMed: | Conjugated linolenic acid is slowly absorbed in rat intestine, but quickly converted to conjugated linoleic acid. |
| PubMed: | Growth inhibition and apoptosis induction by all-trans-conjugated linolenic acids on human colon cancer cells. |
| PubMed: | Conjugated fatty acids accumulate to high levels in phospholipids of metabolically engineered soybean and Arabidopsis seeds. |
| PubMed: | Lipids as renewable resources: current state of chemical and biotechnological conversion and diversification. |
| PubMed: | Lack of chemopreventive effects of alpha-eleostearic acid on 7,12-dimethylbenz[a]anthracene (DMBA) and 1,2-dimethylhydrazine (DMH)-induced mammary and colon carcinogenesis in female Sprague-Dawley rats. |
| PubMed: | Inhibitory action of conjugated C18-fatty acids on DNA polymerases and DNA topoisomerases. |
| PubMed: | Oxidation rate of conjugated linoleic acid and conjugated linolenic acid is slowed by triacylglycerol esterification and alpha-tocopherol. |
| PubMed: | Alpha-eleostearic acid (9Z11E13E-18:3) is quickly converted to conjugated linoleic acid (9Z11E-18:2) in rats. |
| PubMed: | Recommended methods of fatty acid methylester preparation for conjugated dienes and trienes in food and biological samples. |
| PubMed: | Tumor growth suppression by alpha-eleostearic acid, a linolenic acid isomer with a conjugated triene system, via lipid peroxidation. |
| PubMed: | Molecular analysis of a bifunctional fatty acid conjugase/desaturase from tung. Implications for the evolution of plant fatty acid diversity. |
| PubMed: | Effect of dietary tung oil on the growth and lipid metabolism of laying hens. |
| PubMed: | An ultraviolet spectrophotometric assay for measuring lipase activity using long-chain triacyglycerols from Aleurites fordii seeds. |
| PubMed: | Dietary effects of conjugated octadecatrienoic fatty acid (9 cis, 11 trans, 13 trans) levels on blood lipids and nonenzymatic in vitro lipid peroxidation in rats. |
| PubMed: | In Vivo Studies of the Biosynthesis of [alpha]-Eleostearic Acid in the Seed of Momordica charantia L. |
| PubMed: | Isomerization of the double bonds of a conjugated fatty acid during beta-oxidation. |
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