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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 283.50 °C. @ 760.00 mm Hg
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| Boiling Point: | 490.70 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 424.00 °F. TCC ( 217.70 °C. ) (est)
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| logP (o/w): | 11.060 (est) |
| Soluble in: |
| | water, 9.552e-005 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for taraxerol usage levels up to: | | | not for fragrance use.
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| Recommendation for taraxerol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 92097 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | (3S,4aR,6aR,6aS,8aR,12aR,14aR,14bR)-4,4,6a,6a,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,8,9,10,12,12a,13,14,14a-tetradecahydropicen-3-ol |
| Chemidplus: | 0000127220 |
References:
| | (3S,4aR,6aR,6aS,8aR,12aR,14aR,14bR)-4,4,6a,6a,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,8,9,10,12,12a,13,14,14a-tetradecahydropicen-3-ol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 92097 |
| Pubchem (sid): | 135047910 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | alnulin | | (3beta)-dextro- | friedoolean-14-en-3-ol | | D- | friedoolean-14-en-3b-ol | | dextro- | friedoolean-14-en-3beta-ol | | (3S,4aR,6aR,6aS,8aR,12aR,14aR,14bR)-4,4,6a,6a,8a,11,11,14b- | octamethyl-1,2,3,4a,5,6,8,9,10,12,12a,13,14,14a-tetradecahydropicen-3-ol | | iso | olean-14-en-3b-ol | | | skimmiol | | | tiliadin |
Articles:
| PubMed: | Pereskia aculeata miller leaves present in vivo topical anti-inflammatory activity in models of acute and chronic dermatitis. |
| PubMed: | Effects of Lupenone, Lupeol, and Taraxerol Derived from Adenophora triphylla on the Gene Expression and Production of Airway MUC5AC Mucin. |
| PubMed: | Hydrogen isotope response to changing salinity and rainfall in Australian mangroves. |
| PubMed: | Occurrence of taraxerol and taraxasterol in medicinal plants. |
| PubMed: | Antinociceptive and anti-inflammatory activities of Schefflera octophylla extracts. |
| PubMed: | Cardanols, long chain cyclohexenones and cyclohexenols from Lannea schimperi (Anacardiaceae). |
| PubMed: | [Chemical constituents of Clerodendrum trichotomum Leaves]. |
| PubMed: | Distribution and sources of lipid compound series in sediment cores of the southern South China Sea. |
| PubMed: | Abroma augusta L. (Malvaceae) leaf extract attenuates diabetes induced nephropathy and cardiomyopathy via inhibition of oxidative stress and inflammatory response. |
| PubMed: | Effects of single, binary and tertiary combinations with Jatropha gossypifolia and other plant-derived molluscicides on reproduction and survival of the snail Lymnaea acuminata. |
| PubMed: | [Study on chemical constituents from leaf of Bombax ceiba (II)]. |
| PubMed: | A new triterpenoid from Sapium baccatum (Euphorbiaceae). |
| PubMed: | Cholinesterase inhibitory triterpenoids from the bark of Garcinia hombroniana. |
| PubMed: | A new cinnamoylglycoflavonoid, antimycobacterial and antioxidant constituents from Heritiera littoralis leaf extracts. |
| PubMed: | Interactions of antiparasitic sterols with sterol 14α-demethylase (CYP51) of human pathogens. |
| PubMed: | Triterpenes from Euphorbia hirta and their cytotoxicity. |
| PubMed: | A new taraxerol derivative from the roots of Microcos tomentosa. |
| PubMed: | Anti-plasmodial activity of some Zulu medicinal plants and of some triterpenes isolated from them. |
| PubMed: | Antimicrobial activity and cytotoxicity of triterpenes isolated from leaves of Maytenus undata (Celastraceae). |
| PubMed: | [Study on chemical constituents of root bark of Discocleidion rufescens]. |
| PubMed: | Taraxerol inhibits LPS-induced inflammatory responses through suppression of TAK1 and Akt activation. |
| PubMed: | New sesquiterpenes and phenolic compound from Ficus foveolata. |
| PubMed: | Reversal of dexamethasone induced insulin resistance in 3T3L1 adipocytes by 3β-taraxerol of Mangifera indica. |
| PubMed: | Standardized Clitoria ternatea leaf extract as hyaluronidase, elastase and matrix-metalloproteinase-1 inhibitor. |
| PubMed: | Production of triterpenoid anti-cancer compound taraxerol in Agrobacterium-transformed root cultures of butterfly pea (Clitoria ternatea L.). |
| PubMed: | Source correlation of biomarkers in a mangrove ecosystem on Santa Catarina Island in southern Brazil. |
| PubMed: | Impact of Taraxerol in combination with extract of Euphorbia tirucalli plant on biological parameters of Lymnaea acuminata. |
| PubMed: | Effect of bioactive compounds extracted from euphorbious plants on hematological and biochemical parameters of Channa punctatus. |
| PubMed: | [Studies on the chemical constituents of Codonopsis pilosula]. |
| PubMed: | [Effects of taraxerol and taraxerol acetate on cell cycle and apoptosis of human gastric epithelial cell line AGS]. |
| PubMed: | Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. |
| PubMed: | Anti-inflammatory diterpene from Thyrsanthera suborbicularis. |
| PubMed: | Antiproliferative constituents of the roots of Conyza canadensis. |
| PubMed: | [Studies on the triterpenoids of Vitex trifolia]. |
| PubMed: | [Chemical constituents of Discocleidion rufescens]. |
| PubMed: | Determination of the phenolic content and antioxidant potential of crude extracts and isolated compounds from leaves of Cordia multispicata and Tournefortia bicolor. |
| PubMed: | Cloning and characterization of oxidosqualene cyclases from Kalanchoe daigremontiana: enzymes catalyzing up to 10 rearrangement steps yielding friedelin and other triterpenoids. |
| PubMed: | Triterpenoids from the roots of Pterospermum heterophyllum Hance. |
| PubMed: | [Terpenoids from Euphorbia antiquorum L.]. |
| PubMed: | [Studies on the chemical constituents from Euphorbia chrysocoma]. |
| PubMed: | 3beta-taraxerol of Mangifera indica, a PI3K dependent dual activator of glucose transport and glycogen synthesis in 3T3-L1 adipocytes. |
| PubMed: | Antimicrobial and cytotoxic constituents from leaves of Sapium baccatum. |
| PubMed: | [Study on the chemical constituents of Uvaria microcarpa]. |
| PubMed: | Active compounds against tinea pedis dermatophytes from Ageratina pichinchensis var. bustamenta. |
| PubMed: | Antifungal activity of Eugenia umbelliflora against dermatophytes. |
| PubMed: | Phytochemical analyses and gastroprotective effects of Eugenia umbelliflora (Myrtaceae) on experimental gastric ulcers. |
| PubMed: | Isolation and characterization of xanthine oxidase inhibitory constituents of Pyrenacantha staudtii. |
| PubMed: | Antiproliferative compounds of Helmiopsis sphaerocarpa from the Madagascar rainforest. |
| PubMed: | [Studies on chemical constituents of root tuber of cultivated Pseudostellaria heterophylla (Zheshen No. 1)]. |
| PubMed: | [Studies on chemical constituents from roots of Pterospermum heterophyllum]. |
| PubMed: | [Chemical constituents in the leave of Rhizophora stylosa L and their biological activities]. |
| PubMed: | Photochemical alteration of 3-oxygenated triterpenoids: implications for the origin of 3,4-seco-triterpenoids in sediments. |
| PubMed: | New diterpenoids and the bioactivity of Erythrophleum fordii. |
| PubMed: | A new cytotoxic prenylated dihydrobenzofuran derivative and other chemical constituents from the rhizomes of Atractylodes lancea DC. |
| PubMed: | Triterpenoids and a sterol from the stem-bark of Styrax japonica and their protein tyrosine phosphatase 1B inhibitory activities. |
| PubMed: | [Studies on chemical constituents from whole plants of Crossostephium chinense]. |
| PubMed: | Pentacyclic triterpenoids from the mangrove plant Rhizophora stylosa. |
| PubMed: | [Triterpenoids and steroids from Excoecaria agallocha]. |
| PubMed: | Validation of HPTLC method for the analysis of taraxerol in Clitoria ternatea. |
| PubMed: | Lipid biomarkers in suspended particles from a subtropical estuary: assessment of seasonal changes in sources and transport of organic matter. |
| PubMed: | Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae. |
| PubMed: | [Studies on the chemical constituents of Vaccinium iteophyllum]. |
| PubMed: | Chemical constituents from the roots of Homonoia riparia. |
| PubMed: | Identification and determination of triterpenoids in Hieracium pilosella L. |
| PubMed: | Pentacyclic triterpenes with selective bioactivity from Sebastiania adenophora leaves, Euphorbiaceae. |
| PubMed: | Two novel C29-5beta-sterols from the stems of Opuntia dillenii. |
| PubMed: | [Study on the chemical constituents of Mitragyna rotundifolia]. |
| PubMed: | Oleanane-type triterpenes of Embelia schimperi leaves. |
| PubMed: | Two new 18-en-oleane derivatives from marine mangrove plant, Barringtonia racemosa. |
| PubMed: | Natural product biomarkers as indicators of sources and transport of sedimentary organic matter in a subtropical river. |
| PubMed: | The chemical constituents of Rhododendron ovatum Planch. |
| PubMed: | New furofuran and butyrolactone lignans with antioxidant activity from the stem bark of Styrax japonica. |
| PubMed: | [Studies on chemical constituents of Clerodendrum bungei]. |
| PubMed: | A new triterpenoid: taraxerol-3-beta-O-tridecyl ether from Derris triofoliata. |
| PubMed: | Studies on the chemical constituents of the roots of Rhododendron molle G. Don. |
| PubMed: | New cytotoxic terpenoids from the wood of Vepris punctata from the Madagascar Rainforest. |
| PubMed: | Pentacyclic triterpenoid esters from the fruits of Bruguiera cylindrica. |
| PubMed: | Acetylcholinesterase inhibitors from the twigs of Vaccinium oldhami Miquel. |
| PubMed: | Taraxer-14-en-3beta-ol, an anti-inflammatory compound from Sterculia foetida L. |
| PubMed: | Potential cancer chemopreventive constituents of the leaves of Macaranga triloba. |
| PubMed: | [Studies on chemical constituents of Uvaria macrophylia]. |
| PubMed: | [A study on chemical components of Tetrastigma hemsleyanum Diels et Gilg. Native to China]. |
| PubMed: | Anti-inflammatory and antimicrobial activities of triterpenoids from Strobilanthes callosus nees. |
| PubMed: | Cytotoxic principles from Ventilago leiocarpa. |
| PubMed: | A phytochemical investigation of Alchornea latifolia. |
| PubMed: | Taraxerol acetate at 100 K. |
| PubMed: | Rhizophora mangle (Rhizophoraceae) triterpenoids with insecticidal activity. |
| PubMed: | Anti-carcinogenic activity of Taraxacum plant. II. |
| PubMed: | Distribution of pyranocoumarins in Calophyllum cordato-oblongum. |
| PubMed: | Triterpene alcohols from the flowers of compositae and their anti-inflammatory effects. |
| PubMed: | [Chemical components of Codonopsis pilosula (Franch.) Nannf. var. volubilis (Nannf.) L.T. Shen]. |
| PubMed: | [Chemical constituents in the leaves of Mangifera persiciformis C.Y. Wu et Y.L. Ming]. |
| PubMed: | [Chemical constituents of Sageretia theezans Brongn]. |
| PubMed: | Antibacterial, antifungal and anthelmintic activities of root barks of Uvaria hookeri and Uvaria narum. |
| PubMed: | [Chemical constituents of the leaves of Acanthopanax trifoliatus (Linn) Merr]. |
| PubMed: | Isolation of myricadiol, myricitrin, taraxerol, and taraxerone from Myrica cerifera L. root bark. |
| PubMed: | [Studies on the neutral constituents of Pachysandra terminalis Sieb. et Zucc. II. Identification of taraxerol and isolation of compound-3A and 3B]. |
| PubMed: | [Studies on the constituents of Acanthopanax sciadophylloides Franch. et Sav. 3. Higher fatty acid esters of taraxerol]. |
| PubMed: | Taraxerol from Careya arborea. |
| PubMed: | The isolation of taraxerol, taraxeryl acetate, and taraxerone from Crossostephium chinense Makino (Compositae). |
| PubMed: | TARAXEROL FROM CLITORIA TERNATEA LINN. |
| PubMed: | A new source of taraxerol. |
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