sodium calcium alginate
alginic acid calcium sodium salt
 
Notes:
Used as a food additive [EAFUS]
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CAS Number: 12698-40-7 
XlogP3-AA: -3.70 (est)
Molecular Weight: 398.31894000
Formula: C14 H22 O13
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Category: thickeners, gelling agents, stabalizers and emulsifiers
 
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FDA Mainterm (SATF):12698-40-7 ; ALGINATE, SODIUM CALCIUM
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Physical Properties:
Food Chemicals Codex Listed: No
Boiling Point: 732.47 °C. @ 760.00 mm Hg (est)
Flash Point: 514.00 °F. TCC ( 267.80 °C. ) (est)
logP (o/w): -3.203 (est)
Similar Items: note
alginic acid
alginic acid ammonium salt
alginic acid calcium salt
alginic acid ester with 1,2-propane diol
alginic acid potassium salt
alginic acid sodium salt
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: thickeners, gelling agents, stabalizers and emulsifiers
Recommendation for sodium calcium alginate usage levels up to:
 not for fragrance use.
 
Recommendation for sodium calcium alginate flavor usage levels up to:
 not for flavor use.
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Safety References:
AIDS Citations: Search
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EPA ACToR: Toxicology Data
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Laboratory Chemical Safety Summary : 6850754
National Institute of Allergy and Infectious Diseases: Data
 6-(2-carboxy-4,5-dihydroxy-6-methoxyoxan-3-yl)oxy-4,5-dihydroxy-3-methoxyoxane-2-carboxylic acid
Chemidplus: 0012698407
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References:
 6-(2-carboxy-4,5-dihydroxy-6-methoxyoxan-3-yl)oxy-4,5-dihydroxy-3-methoxyoxane-2-carboxylic acid
Pubchem (cid): 6850754
Pubchem (sid): 135350700
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Other Information:
FDA Substances Added to Food (formerly EAFUS): View
HMDB (The Human Metabolome Database): Search
FooDB: FDB008907
FDA Listing of Food Additive Status: View
ChemSpider: View
Formulations/Preparations:
•it consists chiefly of sodium salt of alginic acid, polyuronic acid composed of beta d-mannuronic acid residues linked so that carboxyl group of each unit is free while aldehyde group is shielded by glycosidic linkage. •all derivatives of alginic acid designated by the generic term algin. most commonly used algin compound is sodium alginate often used interchangeably. •trade names include alginate, sfc; cecalgum, sanofi; dialgin, diamalt; keltex, kelco; lamitex, protan; manutex, kelco. •dental alginates are powder mixtures with the following composition: sodium alginate (10 ? 20 wt %), calcium sulfate (10 wt %), trisodium phosphate (1 ? 4 wt %), diatomite (70 ? 80 wt %), color and flavor (1 ? 2 wt %).
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
 alginic acid calcium sodium salt
 calcium sodium alginate
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Articles:
PubMed: The evaluation of resorbable haemostatic wound dressings in contact with blood in vitro.
PubMed: Adsorption of ochratoxin A from grape juice by yeast cells immobilised in calcium alginate beads.
PubMed: Gelling process for sodium alginate: New technical approach by using calcium rich micro-spheres.
PubMed: In-vivo evaluation of clindamycin release from glyceryl monooleate-alginate microspheres by NIR spectroscopy.
PubMed: Evaluation of Six Split-thickness Skin Graft Donor-site Dressing Materials in a Swine Model.
PubMed: Novel synovial fluid recovery method allows for quantification of a marker of arthritis in mice.
PubMed: Bacterial and Candida albicans adhesion on rapid prototyping-produced 3D-scaffolds manufactured as bone replacement materials.
PubMed: A prospective controlled clinical study of skin donor sites treated with a 1-4,2-acetamide-deoxy-B-D-glucan polymer: a preliminary report.
PubMed: Evaluation of a combined calcium sodium alginate and bio-occlusive membrane dressing in the management of split-thickness skin graft donor sites.
PubMed: Melgisorb: a highly absorbent calcium/sodium alginate dressing.
PubMed: [Pure calcium-sodium alginate dressing. Multicenter evaluation of chronic cutaneous lesions].
PubMed: Successful treatment of toxic epidermal necrolysis with calcium sodium alginate fiber.
PubMed: Dressings for treating cavity wounds.
PubMed: CT and MR appearance of otolaryngologic packing materials.
PubMed: Subperiosteal behaviour of alginate and cellulose wound dressing materials.
PubMed: Kaltostat.
PubMed: An evaluation of the local reaction and biodegradation of calcium sodium alginate (Kaltostat) following subcutaneous implantation in the rat.
PubMed: Early complications of packing after nasal surgery with three different materials.
PubMed: Symptomatic foreign body reaction to haemostatic alginate.
PubMed: Tissue response to a haemostatic alginate wound dressing in tooth extraction sockets.
PubMed: A comparative study of calcium sodium alginate (Kaltostat) and bismuth tribromophenate (Xeroform) packing in the management of epistaxis.
PubMed: Treating a patient with a sacral pressure sore.
PubMed: A randomized study to compare calcium sodium alginate fibre with two commonly used materials for packing after nasal surgery.
PubMed: Comparison of calcium sodium alginate (KALTOSTAT) and porcine xenograft (E-Z DERM) in the healing of split-thickness skin graft donor sites.
PubMed: Treatment of donor sites--calcium alginate versus paraffin gauze.
PubMed: Influence of surfactant on the properties of granules and tablets containing sodium calcium alginate.
PubMed: Effect of intragranular and extragranular disintegrating agents on particle size of disintegrated tablets.
PubMed: Disintegration properties of calcium phosphate dibasic dihydrate tablets.
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