terpenes and terpenoids
limonene fraction of terpenes and terpenoids obtained from turpentine oil or citrus
 
Notes:
tsca definition 2008: a complex combination of terpenes derived from oil of turpentine or citrus oils by fractionation or isomerization of other terpene fractions. contains at least 80% limonene, the remainder being other terpene hydrocarbons. may contain trace amounts of alcohols, ethers, aldehydes, or ketones.
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CAS Number: 65996-98-7 
ECHA EC Number: 266-034-5
Category: fragrance agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
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Physical Properties:
Appearance: colorless to yellow clear liquid (est)
Food Chemicals Codex Listed: No
Soluble in:
 water, 4.581 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data2
CosIng: cosmetic data
Cosmetic Uses: perfuming agents
solvents
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: fragrance agents
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
 
Recommendation for terpenes and terpenoids flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
EPA Substance Registry Services (TSCA): 65996-98-7
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
SCCNFP: opinion
Chemidplus: 065996987
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References:
Canada Domestic Sub. List: 65996-98-7
Pubchem (sid): 135298864
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Other Information:
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
 limonene fraction of terpenes and terpenoids obtained from turpentine oil or citrus
 terpenes and terpenoids, limonene fraction
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Articles:
PubMed: Phytochemical constituents as future antidepressants: a comprehensive review.
J-Stage: Cleavage of a-Dicarbonyl Compounds by Terpene Hydroperoxide
PubMed: Non-Conventional Yeasts Whole Cells as Efficient Biocatalysts for the Production of Flavors and Fragrances.
PubMed: Terpenes and terpenoids in chemical sensitivity.
PubMed: Evaluation of the performance of Torulaspora delbrueckii, Williopsis saturnus, and Kluyveromyces lactis in lychee wine fermentation.
PubMed: Building terpene production platforms in yeast.
PubMed: Evaporation kinetics of laboratory-generated secondary organic aerosols at elevated relative humidity.
PubMed: Advanced analytical techniques for the extraction and characterization of plant-derived essential oils by gas chromatography with mass spectrometry.
PubMed: Heterologous fermentation of a diterpene from Alternaria brassisicola.
PubMed: Transient secondary organic aerosol formation from limonene ozonolysis in indoor environments: impacts of air exchange rates and initial concentration ratios.
PubMed: Foreword. Terpenes and terpenoids.
PubMed: Genetic and metabolic engineering of microorganisms for the development of new flavor compounds from terpenic substrates.
PubMed: One-step column chromatographic extraction with gradient elution followed by automatic separation of volatiles, flavonoids and polysaccharides from Citrus grandis.
PubMed: Mushroom immunomodulators: unique molecules with unlimited applications.
PubMed: Temperature-dependent Henry's law constants of atmospheric organics of biogenic origin.
PubMed: Indoor secondary organic aerosol formation initiated from reactions between ozone and surface-sorbed D-limonene.
PubMed: Stability assessment of gas mixtures containing monoterpenes in varying cylinder materials and treatments.
PubMed: Physiological and transcriptional responses of Saccharomyces cerevisiae to d-limonene show changes to the cell wall but not to the plasma membrane.
PubMed: The fate of dermally applied [14C]d-limonene in rats and humans.
PubMed: Using volatile organic compounds to enhance atrazine biodegradation in a biobed system.
PubMed: Medicinal plant complexes of Salvia subgenus Calosphace: an ethnobotanical study of new world sages.
PubMed: A novel device for the study of antimicrobial activity by vapor-contact of volatile substances on food products.
PubMed: Brown carbon formation from ketoaldehydes of biogenic monoterpenest.
PubMed: Antioxidant activities of extracts from teas prepared from medicinal plants, Morus alba L., Camellia sinensis L., and Cudrania tricuspidata , and their volatile components.
PubMed: Degradation of terpenes and terpenoids from Mediterranean rangelands by mixed rumen bacteria in vitro.
PubMed: α-Terpinene, an antioxidant in tea tree oil, autoxidizes rapidly to skin allergens on air exposure.
PubMed: Multidimensional enantio gas chromtography/mass spectrometry and gas chromatography-combustion-isotopic ratio mass spectrometry for the authenticity assessment of lime essential oils (C. aurantifolia Swingle and C. latifolia Tanaka).
PubMed: Essential oils from aromatic herbs as antimicrobial agents.
PubMed: Determination of the chemical composition and in vitro antioxidant activities of essential oil and methanol extracts of Echinophora platyloba DC.
PubMed: Flavored waters: influence of ingredients on antioxidant capacity and terpenoid profile by HS-SPME/GC-MS.
PubMed: Comparison of Eucalyptus cinerea essential oils produced by hydrodistillation and supercritical carbon dioxide extraction.
PubMed: Saccharomyces cerevisiae: a potential stereospecific reduction tool for biotransformation of mono- and sesquiterpenoids.
PubMed: Dynamic solid phase microextraction sampling for reactive terpenes in the presence of ozone.
PubMed: High-resolution electrospray ionization mass spectrometry analysis of water-soluble organic aerosols collected with a particle into liquid sampler.
PubMed: Adipose tissue accumulation of d-limonene with the consumption of a lemonade preparation rich in d-limonene content.
PubMed: A chamber study of secondary organic aerosol formation by limonene ozonolysis.
PubMed: Selective removal of monoterpenes from bergamot oil by inclusion in deoxycholic acid.
PubMed: Microbial inhibitory and radical scavenging activities of cold-pressed terpeneless Valencia orange (Citrus sinensis) oil in different dispersing agents.
PubMed: Rosmarinus officinalis L.: chemical modifications of the essential oil and evaluation of antioxidant and antimicrobial activity.
PubMed: Time-resolved molecular characterization of limonene/ozone aerosol using high-resolution electrospray ionization mass spectrometry.
PubMed: Mass spectra deconvolution of low, medium, and high volatility biogenic secondary organic aerosol.
PubMed: Intraplantar injection of bergamot essential oil into the mouse hindpaw: effects on capsaicin-induced nociceptive behaviors.
PubMed: Antimicrobial activity of commercial citrus-based natural extracts against Escherichia coli O157:H7 isolates and mutant strains.
PubMed: Organosulfate formation in biogenic secondary organic aerosol.
PubMed: Effect of Tilia x viridis flower extract on the proliferation of a lymphoma cell line and on normal murine lymphocytes: contribution of monoterpenes, especially limonene.
PubMed: Biological effects of essential oils--a review.
PubMed: Oligomers in the early stage of biogenic secondary organic aerosol formation and growth.
PubMed: Characterisation of VOCs emitted by open cells receiving municipal solid waste.
PubMed: Formulation development of transdermal dosage forms: quantitative structure-activity relationship model for predicting activities of terpenes that enhance drug penetration through human skin.
PubMed: Efflorescence transitions of ammonium sulfate particles coated with secondary organic aerosol.
PubMed: Changes in the enantiomeric distribution of selected volatile constituents of Mentha pulegium L. powders caused by hot water treatment.
PubMed: Evaluation of characteristic aroma compounds of Citrus natsudaidai Hayata (Natsudaidai) cold-pressed peel oil.
PubMed: Chemical composition of volatiles in Sardinian myrtle (Myrtus communis L.) alcoholic extracts and essential oils.
PubMed: Antioxidant and antimycobacterial activities of Tabernaemontana catharinensis extracts obtained by supercritical CO2 + cosolvent.
PubMed: Mass transfer of terpenes through a silicone rubber membrane in a liquid-liquid contacting system.
PubMed: Chemical composition and anti-inflammatory activity of the volatile fractions from the bark of eight Mexican Bursera species.
PubMed: Selected oxidized fragrance terpenes are common contact allergens.
PubMed: Inhibition of P-glycoprotein-mediated transport by extracts of and monoterpenoids contained in Zanthoxyli fructus.
PubMed: Volatile organic compounds produced during the aerobic biological processing of municipal solid waste in a pilot plant.
PubMed: The effect on human eye blink frequency of exposure to limonene oxidation products and methacrolein.
PubMed: Stabilization of aroma compounds through sorption-release by packaging polymers.
PubMed: Characteristic odor components of Citrus reticulata Blanco (ponkan) cold-pressed oil.
PubMed: [Studies on analysis of terpene resin in imported chewing gums].
PubMed: High power ultrasound effects on lipid oxidation of refined sunflower oil.
PubMed: Induction of apoptosis by Citrus paradisi essential oil in human leukemic (HL-60) cells.
PubMed: Patch testing with oxidized R-(+)-limonene and its hydroperoxide fraction.
PubMed: Character impact odorants of Citrus Hallabong [(C. unshiu Marcov x C. sinensis Osbeck) x C. reticulata Blanco] cold-pressed peel oil.
PubMed: [A study on the chemical components of essential oil of oak moss concrete by gas chromatography/mass spectrometry].
PubMed: Characteristic odor components of Citrus sphaerocarpa Tanaka (Kabosu) cold-pressed peel oil.
PubMed: Seasonal changes in the composition of the essential oil extract of East Mediterranean sage (Salvia libanotica) and its toxicity in mice.
PubMed: Antibacterial and molluscicidal activities of the essential oil of Chrysanthemum viscidehirtum.
PubMed: Characterization of the odor-active volatiles in citrus Hyuganatsu (Citrus tamurana Hort. ex Tanaka).
PubMed: Identification of volatile constituents of Tambourissa leptophylla.
PubMed: [Allergic contact dermatitis to cosmetics containing Melaleuca alternifolia (tea tree oil)].
PubMed: Evaluation of the in vivo interaction of methyl tert-butyl ether with alpha2u-globulin in male F-344 rats.
PubMed: Terpenoid composition of the wound-induced bark exudate of Commiphora tenuis from Ethiopia.
PubMed: Monoterpene synthases from grand fir (Abies grandis). cDNA isolation, characterization, and functional expression of myrcene synthase, (-)-(4S)-limonene synthase, and (-)-(1S,5S)-pinene synthase.
PubMed: In vitro uptake of methyl tert-butyl ether in male rat kidney: use of a two-compartment model to describe protein interactions.
PubMed: Protein kinase C activation after cellular adhesion on fibronectin: partial suppression after inhibition of protein isoprenylation.
PubMed: Contact allergy to oxidized d-limonene among dermatitis patients.
PubMed: Aerobic biodegradation of selected monoterpenes.
PubMed: Identifying functional domains within terpene cyclases using a domain-swapping strategy.
PubMed: Decomposition of Terpenes by Ozone during Sampling on Tenax.
PubMed: Hydroperoxides in oxidized d-limonene identified as potent contact allergens.
PubMed: d-Limonene-induced male rat-specific nephrotoxicity: evaluation of the association between d-limonene and alpha 2u-globulin.
PubMed: Marine terpenes and terpenoids. V. Oxidation of sarcophytol A, a potent anti-tumor-promoter from the soft coral Sarcophyton glaucum.
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