Articles:
2-hydroxy-4H-1,3,2-benzodioxabismin-4-one
Notes:
bismuth subsalicylate is the active ingredient of pepto-bismol and in kaopectate; used to treat nausea, heartburn, indigestion, upset stomach, diarrhea and other temporary discomforts of the stomach; used with azoles and other drugs to treat helicobacter.
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American International Chemical, Inc. Consistent sources North American supplier for globally sourced ingredients. AIC is a Westborough, MA based ISO Certified sales and marketing company serving the food, pharmaceutical, nutritional, personal care, biotech, and industrial markets of North America since 1972. Our success is a result of a company culture built on customer needs, along with partnerships with global manufacturers committed to the rigors and demands of the North American market. Our team of Sales Representatives, along with our network of strategically located warehouses are ready to supply product when and where you need it. Email: Info Voice: (800) 238-0001 Facebook Twitter Linkedin Products List: View Product(s): BSSOSP Bismuth Subsalicylate Used as active ingredient for liquid and tablet antacids, and antiemetics.
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BOC Sciences Best of Chemicals Supplier Quality supplier of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Email: Marketing US Email: Marketing Email: Sales US Email: Sales Voice: 1-631-485-4226 Fax: 1-631-614-7828 US Voice: 1-631-485-4226 US Fax: 1-631-614-7828 Europe 44-203-286-1088 Facebook Twitter Linkedin Blog Get the App! Product(s): 14882-18-9 Bismuth Subsalicylate >98% Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2.
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Penta International Corporation Chemistry innovation At Penta, our products and services help businesses do business better. For over 30 years, Penta Manufacturing Company has played a growing role in worldwide chemistry innovations and applications. As an industry leader, Penta continues to pioneer chemistry-based solutions for practically every area of commerce. Our products and expertise have helped fuel technical advances in dozens of commercial applications including flavoring, coloring, fragrances and chemical processes. US Email: Technical Services US Email: Sales US Voice: (973) 740-2300 US Fax: (973) 740-1839 Product(s): 02-32700 BISMUTH SUBSALICYLATE USP POWDER
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| CAS Number: | 14882-18-9 |  3D/inchi
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| Other(deleted CASRN): | 55200-42-5 | |
| ECHA EINECS - REACH Pre-Reg: | 238-953-1 | |
| FDA UNII: | 62TEY51RR1 | |
| MDL: | MFCD00085368 | |
| Molecular Weight: | 362.09405000 | |
| Formula: | C7 H5 Bi O4 | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est) |
| Soluble in: | |
| water, 43.97 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| American Elements |
| Bismuth Subsalicylate 99%
Odor: characteristic Use: Bismuth Subsalicylate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards. |
| American International Chemical, LLC. |
| Bismuth Subsalicylate
Odor: characterisitc Use: Used as active ingredient for liquid and tablet antacids, and antiemetics. |
| BOC Sciences |
| For experimental / research use only. |
| Bismuth Subsalicylate >98%
Odor: characteristic Use: Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostaglandin G/H Synthase 1/2. |
| George Uhe Company |
| BISMUTH SUBSALICYLATE POWDER USP |
| Penta International |
| BISMUTH SUBSALICYLATE USP POWDER |
| Sigma-Aldrich: Aldrich |
| For experimental / research use only. |
| Bismuth(III) subsalicylate 99.9% trace metals basis |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
|
intramuscular-man LDLo 60 mg/kg/26W-I KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" American Journal of Clinical Pathology. Vol. 14, Pg. 392, 1944. intramuscular-man TDLo 17 mg/kg/5W-I GASTROINTESTINAL: OTHER CHANGES American Journal of Syphilis, Gonorrhea and Venereal Diseases. Vol. 26, Pg. 84, 1942. | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | information only not used for fragrances or flavors | ||
| Recommendation for bismuth subsalicylate usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for bismuth subsalicylate flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| Chemical Carcinogenesis Research Information System: | Search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 14882-18-9 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 16682734 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| 1,3,2?2-benzodioxabismin-4-one;hydrate | |
| Chemidplus: | 0008047390 |
| EPA/NOAA CAMEO: | hazardous materials |
References:
| 1,3,2?2-benzodioxabismin-4-one;hydrate | |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 14882-18-9 |
| Pubchem (cid): | 16682734 |
| Pubchem (sid): | 135354417 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| KEGG (GenomeNet): | C07870 |
| HMDB (The Human Metabolome Database): | HMDB15408 |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| 4H-1,3,2- | benzodioxabismin-4-one, 2-hydroxy- |
| 1,3,2?2- | benzodioxabismin-4-one;hydrate |
| bismukote | |
| bismuth oxide salicylate | |
| bismuth, (2-hydroxybenzoato-O1,O2)oxo- | |
| bismuth(III) subsalicylate | |
| bismuthsubsalicylate | |
| gastro-cote | |
| 2- | hydroxy-4H-1,3,2-benzodioxabismin-4-one |
| pepto-bismol | |
| salicylic acid bismuth basic salt |