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Category: indirect food additives: adhesives and components of coatings
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 0.005839 mg/L @ 25 °C (est) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LD50 25070 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) Toho Igakkai Zasshi. Journal of Medical Society of Toho University. Vol. 10, Pg. 1, 1963.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | indirect food additives: adhesives and components of coatings |
| Recommendation for L-ascorbyl stearate usage levels up to: | | | not for fragrance use.
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| Recommendation for L-ascorbyl stearate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | [(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxyethyl] octadecanoate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 54725318 |
| Pubchem (sid): | 134991129 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| L- | ascorbic acid, 6-stearate | | L- | ascorbol stearate | | [(2S)-2-[(2R)-3,4- | dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxyethyl] octadecanoate | | 6-( | stearoyloxy)-L-ascorbic acid | | 6-O- | stearylascorbic acid | | | vitamin C monostearate |
Articles:
| PubMed: | Ascorbyl Stearate Promotes Apoptosis Through Intrinsic Mitochondrial Pathway in HeLa Cancer Cells. |
| PubMed: | Spray Drying of Rhodomyrtus tomentosa (Ait.) Hassk. Flavonoids Extract: Optimization and Physicochemical, Morphological, and Antioxidant Properties. |
| PubMed: | Metabolism in orange fruits is driven by photooxidative stress in the leaves. |
| PubMed: | Targeted antitumoral dehydrocrotonin nanoparticles with L-ascorbic acid 6-stearate. |
| PubMed: | P53 enhances ascorbyl stearate-induced G2/M arrest of human ovarian cancer cells. |
| PubMed: | Production of ascorbyl palmitate by surfactant-coated lipase in organic media. |
| PubMed: | Ascorbyl stearate inhibits cell proliferation and tumor growth in human ovarian carcinoma cells by targeting the PI3K/AKT pathway. |
| PubMed: | Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics. |
| PubMed: | L-ascorbic acid microencapsulated with polyacylglycerol monostearate for milk fortification. |
| PubMed: | The microencapsulated ascorbic acid release in vitro and its effect on iron bioavailability. |
| PubMed: | Vitamin C in human health and disease is still a mystery? An overview. |
| PubMed: | Antiproliferative and proapoptotic effect of ascorbyl stearate in human pancreatic cancer cells: association with decreased expression of insulin-like growth factor 1 receptor. |
| PubMed: | Antiproliferative and apoptotic effect of ascorbyl stearate in human glioblastoma multiforme cells: modulation of insulin-like growth factor-I receptor (IGF-IR) expression. |
| PubMed: | A kinetic study of the synthesis of ascorbate fatty acid esters catalysed by immobilized lipase in organic media. |
| PubMed: | Regulation of Tiam1 nucleotide exchange activity by pleckstrin domain binding ligands. |
| PubMed: | Mixtures of Ascorbyl-stearate and Vitamin D3: A Monolayer Study at the Gas/Water Interface |
| PubMed: | Inhibition of human glioma cell proliferation and glutathione S-transferase by ascorbyl esters and interferon. |
| PubMed: | Inhibition of cell proliferation and glutathione S-transferase by ascorbyl esters and interferon in mouse glioma. |
| PubMed: | Carbon tetrachloride-induced alterations in hepatic glutathione and ascorbic acid contents in mice fed a diet containing ascorbate esters. |
| PubMed: | Inhibition of human term placental and fetal liver glutathione-S-transferases by fatty acids and fatty acid esters. |
| PubMed: | Effect of ascorbic acid esters on hepatic glutathione levels in mice treated with a hepatotoxic dose of acetaminophen. |
| PubMed: | Influence of ascorbic acid esters on acetaminophen-induced hepatotoxicity in mice. |
| PubMed: | Absence of promotion potential for calcium L-ascorbate, L-ascorbic dipalmitate, L-ascorbic stearate and erythorbic acid on rat urinary bladder carcinogenesis. |
| PubMed: | Mechanical properties, dissolution behavior and stability to oxidation of L-ascorbylmonostearate microcapsules prepared by a spray-drying polycondensation technique. |
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