desmethoxyyangonin, 15345-89-8

Articles:

PubMed:	Quantitative Determination of Lactones in Piper methysticum (Kava-Kava) by Supercritical Fluid Chromatography.
PubMed:	Kavalactone content and chemotype of kava beverages prepared from roots and rhizomes of Isa and Mahakea varieties and extraction efficiency of kavalactones using different solvents.
PubMed:	A plant kavalactone desmethoxyyangonin prevents inflammation and fulminant hepatitis in mice.
PubMed:	Kavalactone metabolism in rat liver microsomes.
PubMed:	Kavalactone metabolism in the isolated perfused rat liver.
PubMed:	Proposal for a kava quality standardization code.
PubMed:	High-performance liquid chromatography assays for desmethoxyyangonin, methysticin, kavain and their microsomal metabolites.
PubMed:	Efficacy of extracting solvents to chemical components of kava (Piper methysticum) roots.
PubMed:	Evaluation of commercial kava extracts and kavalactone standards for mutagenicity and toxicity using the mammalian cell gene mutation assay in L5178Y mouse lymphoma cells.
PubMed:	Permeability studies of Kavalactones using a Caco-2 cell monolayer model.
PubMed:	Fourier transform ion cyclotron resonance mass spectrometry for the characterisation of kavalactones in the kava plant: elemental formulae confirmation by dual spray accurate mass measurement and structural confirmation by infrared multiphoton dissociation and sustained off-resonance irradiation collision induced dissociation.
PubMed:	Determination of kava lactones and flavonoid glycoside in Scorzonera austriaca by capillary zone electrophoresis.
PubMed:	Kavalactones fail to inhibit alcohol dehydrogenase in vitro.
PubMed:	Extracts and kavalactones of Piper methysticum G. Forst (kava-kava) inhibit P-glycoprotein in vitro.
PubMed:	Pharmacokinetics and disposition of the kavalactone kawain: interaction with kava extract and kavalactones in vivo and in vitro.
PubMed:	Superheated water chromatography-nuclear magnetic resonance spectroscopy of kava lactones.
PubMed:	Determination of kava lactones in food supplements by liquid chromatography-atmospheric pressure chemical ionisation tandem mass spectrometry.
PubMed:	Determination of six kavalactones in dietary supplements and selected functional foods containing Piper methysticum by isocratic liquid chromatography with internal standard.
PubMed:	LC-UV and LC-MS analysis of food and drink products containing kava.
PubMed:	Antimycobacterial compounds from Piper sanctum.
PubMed:	Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23.
PubMed:	Effects of kava (Kava-kava, 'Awa, Yaqona, Piper methysticum) on c-DNA-expressed cytochrome P450 enzymes and human cryopreserved hepatocytes.
PubMed:	Kava does not display metabolic toxicity in a homogeneous cellular assay.
PubMed:	In vitro toxicity of kava alkaloid, pipermethystine, in HepG2 cells compared to kavalactones.
PubMed:	Isolation and synthesis of TNF-alpha release inhibitors from Fijian kawa (Piper methysticum).
PubMed:	Inhibition of human cytochrome P450 activities by kava extract and kavalactones.
PubMed:	Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity.
PubMed:	Drug absorption in vitro model: filter-immobilized artificial membranes. 2. Studies of the permeability properties of lactones in Piper methysticum Forst.
PubMed:	Interaction of various Piper methysticum cultivars with CNS receptors in vitro.
PubMed:	Anxiolytic effects of kava extract and kavalactones in the chick social separation-stress paradigm.
PubMed:	Inhibition of platelet MAO-B by kava pyrone-enriched extract from Piper methysticum Forster (kava-kava).
PubMed:	Effect of kava extract and individual kavapyrones on neurotransmitter levels in the nucleus accumbens of rats.
PubMed:	Influence of genuine kavapyrone enantiomers on the GABA-A binding site.
PubMed:	Contribution to the quantitative and enantioselective determination of kavapyrones by high-performance liquid chromatography on ChiraSpher NT material.
PubMed:	Piper methysticum: enantiomeric separation of kavapyrones by high performance liquid chromatography.
PubMed:	Identification of some human urinary metabolites of the intoxicating beverage kava.
PubMed:	Uptake into mouse brain of four compounds present in the psychoactive beverage kava.