| PubMed: | Isolation and characterization of iron chelators from turmeric (Curcuma longa): selective metal binding by curcuminoids. |
| PubMed: | Turmeric Extract Rescues Ethanol-Induced Developmental Defect in the Zebrafish Model for Fetal Alcohol Spectrum Disorder (FASD). |
| PubMed: | Bisdemethoxycurcumin sensitizes cisplatin-resistant lung cancer cells to chemotherapy by inhibition of CA916798 and PI3K/AKT signaling. |
| PubMed: | Single cell amperometry reveals curcuminoids modulate the release of neurotransmitters during exocytosis from PC12 cells. |
| PubMed: | Bisdemethoxycurcumin in combination with α-PD-L1 antibody boosts immune response against bladder cancer. |
| PubMed: | Determination of oral bioavailability of curcuminoid dispersions and nanoemulsions prepared from Curcuma longa Linnaeus. |
| PubMed: | Curcuminoid Demethylation as an Alternative Metabolism by Human Intestinal Microbiota. |
| PubMed: | Purity Evaluation of Curcuminoids in the Turmeric Extract Obtained by Accelerated Solvent Extraction. |
| PubMed: | Comparison of antioxidant, anticholinesterase, and antidiabetic activities of three curcuminoids isolated from Curcuma longa L. |
| PubMed: | Bisdemethoxycurcumin enhances X-ray-induced apoptosis possibly through p53/Bcl-2 pathway. |
| PubMed: | Production of Curcuminoids in Engineered Escherichia coli. |
| PubMed: | Analysis of different innovative formulations of curcumin for improved relative oral bioavailability in human subjects. |
| PubMed: | Studying the effect of physically-adsorbed coating polymers on the cytotoxic activity of optimized bisdemethoxycurcumin loaded-PLGA nanoparticles. |
| PubMed: | Anti-apoptotic effects of Curcuma longa L. extract and its curcuminoids against blue light-induced cytotoxicity in A2E-laden human retinal pigment epithelial cells. |
| PubMed: | Promising anti-tumor properties of bisdemethoxycurcumin: A naturally occurring curcumin analogue. |
| PubMed: | Investigating the Neuroprotective Effects of Turmeric Extract: Structural Interactions of β-Amyloid Peptide with Single Curcuminoids. |
| PubMed: | Bisdemethoxycurcumin exerts pro-apoptotic effects in human pancreatic adenocarcinoma cells through mitochondrial dysfunction and a GRP78-dependent pathway. |
| PubMed: | Synthesis and biological assessment of novel N-(hydroxy/methoxy)alkyl β-enaminone curcuminoids. |
| PubMed: | Investigation of the binding interactions of Bisdemethoxycurcumin, Diacetylcurcumin and Diacetylbisdemethoxycurcumin with bovine α-lactalbumin by experimental and theoretical analysis. |
| PubMed: | Development of a novel stirrerliquid/solid microextraction method for the separation and enrichment of trace levels of active compounds in traditional Chinese medicine. |
| PubMed: | Investigation by response surface methodology of the combined effect of pH and composition of water-methanol mixtures on the stability of curcuminoids. |
| PubMed: | PNIPAM nanoparticles for targeted and enhanced nose-to-brain delivery of curcuminoids: UPLC/ESI-Q-ToF-MS/MS-based pharmacokinetics and pharmacodynamic evaluation in cerebral ischemia model. |
| PubMed: | The circadian clock modulates anti-cancer properties of curcumin. |
| PubMed: | The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies. |
| PubMed: | BMI1 is downregulated by the natural compound curcumin, but not by bisdemethoxycurcumin and dimethoxycurcumin. |
| PubMed: | Extraction and enrichment of natural pigments from solid samples using ionic liquids and chitosan nanoparticles. |
| PubMed: | Randomized Pharmacokinetic Crossover Study Comparing 2 Curcumin Preparations in Plasma and Rectal Tissue of Healthy Human Volunteers. |
| PubMed: | Amyloid binding properties of curcumin analogues in Alzheimer's disease postmortem brain tissue. |
| PubMed: | Polyhydroxycurcuminoids but not curcumin upregulate neprilysin and can be applied to the prevention of Alzheimer's disease. |
| PubMed: | [Extraction Optimization of Rhizome of Curcuma longa by Response Surface Methodology and Support Vector Regression]. |
| PubMed: | Bisdemethoxycurcumin inhibits ovarian cancer via reducing oxidative stress mediated MMPs expressions. |
| PubMed: | Kinetics of Inhibition of Monoamine Oxidase Using Curcumin and Ellagic Acid. |
| PubMed: | Choleretic Activity of Turmeric and its Active Ingredients. |
| PubMed: | Protective Effects of Minor Components of Curcuminoids on Hydrogen Peroxide-Treated Human HaCaT Keratinocytes. |
| PubMed: | Curcuma longa polyphenols improve insulin-mediated lipid accumulation and attenuate proinflammatory response of 3T3-L1 adipose cells during oxidative stress through regulation of key adipokines and antioxidant enzymes. |
| PubMed: | Screening and quantification of anticancer compounds in traditional Chinese medicine by hollow fiber cell fishing and hollow fiber liquid/solid-phase microextraction. |
| PubMed: | Hepatoprotective Effect and Synergism of Bisdemethoycurcumin against MCD Diet-Induced Nonalcoholic Fatty Liver Disease in Mice. |
| PubMed: | Fast analysis of curcuminoids from turmeric (Curcuma longa L.) by high-performance liquid chromatography using a fused-core column. |
| PubMed: | Synergistic inhibitory effect of scopoletin and bisdemethoxycurcumin on Tetranychus cinnabarinus (Boisduval) (Acari: Tetranychidae). |
| PubMed: | Bisdemethoxycurcumin Inhibits Adipogenesis in 3T3-L1 Preadipocytes and Suppresses Obesity in High-Fat Diet-Fed C57BL/6 Mice. |
| PubMed: | Organometallic rhodium(III) and iridium(III) cyclopentadienyl complexes with curcumin and bisdemethoxycurcumin co-ligands. |
| PubMed: | Bisdemethoxycurcumin (BDMC) Alters Gene Expression-associated Cell Cycle, Cell Migration and Invasion and Tumor Progression in Human Lung Cancer NCI-H460 Cells. |
| PubMed: | Bisdemethoxycurcumin suppresses migration and invasion of highly metastatic 95D lung cancer cells by regulating E-cadherin and vimentin expression, and inducing autophagy. |
| PubMed: | Electron Paramagnetic Resonance Study of the Free Radical Scavenging Capacity of Curcumin and Its Demethoxy and Hydrogenated Derivatives. |
| PubMed: | Curcuminoids Modulate the PKCδ/NADPH Oxidase/Reactive Oxygen Species Signaling Pathway and Suppress Matrix Invasion during Monocyte-Macrophage Differentiation. |
| PubMed: | Selected Phytochemicals and Culinary Plant Extracts Inhibit Fructose Uptake in Caco-2 Cells. |
| PubMed: | Bisdemethoxycurcumin-induced S phase arrest through the inhibition of cyclin A and E and induction of apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathways in human lung cancer NCI H460 cells. |
| PubMed: | Inhibition of lung cancer cells A549 and H460 by curcuminoid extracts and nanoemulsions prepared from Curcuma longa Linnaeus. |
| PubMed: | Bisdemethoxycurcumin induces DNA damage and inhibits DNA repair associated protein expressions in NCI-H460 human lung cancer cells. |
| PubMed: | Efficient separation of curcumin, demethoxycurcumin, and bisdemethoxycurcumin from turmeric using supercritical fluid chromatography: From analytical to preparative scale. |
| PubMed: | A Novel Approach for Overcoming Drug Resistance in Breast Cancer Chemotherapy by Targeting new Synthetic Curcumin Analogues Against Aldehyde Dehydrogenase 1 (ALDH1A1) and Glycogen Synthase Kinase-3 β (GSK-3β). |
| PubMed: | [Study on anti-angiogenesis effect of three curcumin pigments and expression of their relevant factors]. |
| PubMed: | State of the Art Detection System for Curcumin Analog. |
| PubMed: | Role of Wnt Inhibitory Factor-1 in Inhibition of Bisdemethoxycurcumin Mediated Epithelial-to-Mesenchymal Transition in Highly Metastatic Lung Cancer 95D Cells. |
| PubMed: | Pilot-scale subcritical solvent extraction of curcuminoids from Curcuma long L. |
| PubMed: | Evaluation of the protective effects of curcuminoid (curcumin and bisdemethoxycurcumin)-loaded liposomes against bone turnover in a cell-based model of osteoarthritis. |
| PubMed: | Beyond Yellow Curry: Assessing Commercial Curcumin Absorption Technologies. |
| PubMed: | Determination of Curcuminoids in Curcuma longa Linn. by UPLC/Q-TOF-MS: An Application in Turmeric Cultivation. |
| PubMed: | Metabolic engineering of Escherichia coli for the biosynthesis of various phenylpropanoid derivatives. |
| PubMed: | Demethoxycurcumin induces the apoptosis of human lung cancer NCI-H460 cells through the mitochondrial-dependent pathway. |
| PubMed: | Oxidative Transformation of Demethoxy- and Bisdemethoxycurcumin: Products, Mechanism of Formation, and Poisoning of Human Topoisomerase IIα. |
| PubMed: | HPLC method for simultaneous quantitative detection of quercetin and curcuminoids in traditional chinese medicines. |
| PubMed: | Autophagy Accompanied with Bisdemethoxycurcumin-induced Apoptosis in Non-small Cell Lung Cancer Cells. |
| PubMed: | Sulfonation of curcuminoids: characterization and contribution of individual SULT enzymes. |
| PubMed: | Further studies on anti-invasive chemotypes: An excursion from chalcones to curcuminoids. |
| PubMed: | Production of curcuminoids from tyrosine by a metabolically engineered Escherichia coli using caffeic acid as an intermediate. |
| PubMed: | Multispectroscopic and molecular modeling studies on the interaction of two curcuminoids with β-lactoglobulin. |
| PubMed: | Bisdemethoxycurcumin Induces apoptosis in activated hepatic stellate cells via cannabinoid receptor 2. |
| PubMed: | Demethoxycurcumin modulates human P-glycoprotein function via uncompetitive inhibition of ATPase hydrolysis activity. |
| PubMed: | Natural borneol enhances bisdemethoxycurcumin-induced cell cycle arrest in the G2/M phase through up-regulation of intracellular ROS in HepG2 cells. |
| PubMed: | Bisdemethoxycurcumin attenuates gastric adenocarcinoma growth by inducing mitochondrial dysfunction. |
| PubMed: | Apoptosis induction by an analog of curcumin (BDMC-A) in human laryngeal carcinoma cells through intrinsic and extrinsic pathways. |
| PubMed: | Short-term Curcuminoid Supplementation for Chronic Pulmonary Complications due to Sulfur Mustard Intoxication: Positive Results of a Randomized Double-blind Placebo-controlled Trial. |
| PubMed: | Screening of β-secretase and acetylcholinesterase inhibitors from plant resources. |
| PubMed: | Molecularly imprinted polymers for cleanup and selective extraction of curcuminoids in medicinal herbal extracts. |
| PubMed: | Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit morphine's rewarding effect in rats. |
| PubMed: | Functionalized magnetic nanoparticles coupled with mass spectrometry for screening and identification of cyclooxygenase-1 inhibitors from natural products. |
| PubMed: | Inhibitory effect of turmeric curcuminoids on FLT3 expression and cell cycle arrest in the FLT3-overexpressing EoL-1 leukemic cell line. |
| PubMed: | Effects of curcuminoids identified in rhizomes of Curcuma longa on BACE-1 inhibitory and behavioral activity and lifespan of Alzheimer's disease Drosophila models. |
| PubMed: | Differential effects of methoxy group on the interaction of curcuminoids with two major ligand binding sites of human serum albumin. |
| PubMed: | A high-throughput quantification method of curcuminoids and curcumin metabolites in human plasma via high-performance liquid chromatography/tandem mass spectrometry. |
| PubMed: | Comparative absorption of curcumin formulations. |
| PubMed: | Analysis of the anticancer activity of curcuminoids, thiotryptophan and 4-phenoxyphenol derivatives. |
| PubMed: | Optimization and validation of high-performance liquid chromatography method for individual curcuminoids in turmeric by heat-refluxed extraction. |
| PubMed: | Bisdemethoxycurcumin Increases Sirt1 to Antagonize t-BHP-Induced Premature Senescence in WI38 Fibroblast Cells. |
| PubMed: | Antimelanoma and antityrosinase from Alpinia galangal constituents. |
| PubMed: | Bisdemethoxycurcumin suppresses MCF-7 cells proliferation by inducing ROS accumulation and modulating senescence-related pathways. |
| PubMed: | Therapeutic potential of turmeric in Alzheimer's disease: curcumin or curcuminoids? |
| PubMed: | The binding of Curcuma longa extract with bovine serum albumin monitored via time-resolved fluorescence. |
| PubMed: | A comparative study of PNIPAM nanoparticles of curcumin, demethoxycurcumin, and bisdemethoxycurcumin and their effects on oxidative stress markers in experimental stroke. |
| PubMed: | Demethoxycurcumin inhibits energy metabolic and oncogenic signaling pathways through AMPK activation in triple-negative breast cancer cells. |
| PubMed: | Preparation of monodisperse curcumin-imprinted polymer by precipitation polymerization and its application for the extraction of curcuminoids from Curcuma longa L. |
| PubMed: | [Lethal effects of scopoletin and bisdemethoxycurcumin against Tetranychus cinnabarinus Boisd. (Acari: Tetranychidae): a simulation study]. |
| PubMed: | Quantification of curcumin, demethoxycurcumin, and bisdemethoxycurcumin in rodent brain by UHPLC/ESI-Q-TOF-MS/MS after intra-nasal administration of curcuminoids loaded PNIPAM nanoparticles. |
| PubMed: | Simultaneous determination of three Curcuminoids in Curcuma wenyujin Y.H.chen et C.Ling. by liquid chromatography-tandem mass spectrometry combined with pressurized liquid extraction. |
| PubMed: | Simultaneous screening of four epidermal growth factor receptor antagonists from Curcuma longa via cell membrane chromatography online coupled with HPLC-MS. |
| PubMed: | Bisdemethoxycurcumin inhibits PDGF-induced vascular smooth muscle cell motility and proliferation. |
| PubMed: | Demethoxycurcumin, a major active curcuminoid from Curcuma longa, suppresses balloon injury induced vascular smooth muscle cell migration and neointima formation: an in vitro and in vivo study. |
| PubMed: | Preparation and oral bioavailability study of curcuminoid-loaded microemulsion. |
| PubMed: | Curcuminoids distinctly exhibit antioxidant activities and regulate expression of scavenger receptors and heme oxygenase-1. |
| PubMed: | Development of a validated UPLC-qTOF-MS Method for the determination of curcuminoids and their pharmacokinetic study in mice. |
| PubMed: | A novel approach to active compounds identification based on support vector regression model and mean impact value. |
| PubMed: | Correlation between Chemical Composition of Curcuma domestica and Curcuma xanthorrhiza and Their Antioxidant Effect on Human Low-Density Lipoprotein Oxidation. |
| PubMed: | A reduced curcuminoid analog as a novel inducer of fetal hemoglobin. |
| PubMed: | Discovering Bisdemethoxycurcumin from Curcuma longa rhizome as a potent small molecule inhibitor of human pancreatic α-amylase, a target for type-2 diabetes. |
| PubMed: | Neurodegenerative Shielding by Curcumin and Its Derivatives on Brain Lesions Induced by 6-OHDA Model of Parkinson's Disease in Albino Wistar Rats. |
| PubMed: | Demethoxycurcumin modulates prostate cancer cell proliferation via AMPK-induced down-regulation of HSP70 and EGFR. |
| PubMed: | Curcuminoid binding to embryonal carcinoma cells: reductive metabolism, induction of apoptosis, senescence, and inhibition of cell proliferation. |
| PubMed: | Isolation and identification of phase 1 metabolites of curcuminoids in rats. |
| PubMed: | Effect of a herbal extract containing curcumin and piperine on midazolam, flurbiprofen and paracetamol (acetaminophen) pharmacokinetics in healthy volunteers. |
| PubMed: | Characterization of photovoltaic performance of the dye-sensitized solar cell with a novel ruthenium complex having a bisdemethoxycurcumin as a ligand. |
| PubMed: | Curcumin--from molecule to biological function. |
| PubMed: | Anticoagulant activities of curcumin and its derivative. |
| PubMed: | Revisiting curcumin chemistry part I: a new strategy for the synthesis of curcuminoids. |
| PubMed: | Barrier protective activities of curcumin and its derivative. |
| PubMed: | Genomic and nongenomic signaling induced by 1α,25(OH)2-vitamin D3 promotes the recovery of amyloid-β phagocytosis by Alzheimer's disease macrophages. |
| PubMed: | Curcumins promote monocytic gene expression related to β-amyloid and superoxide dismutase clearance. |
| PubMed: | Curcuminoids promote neurite outgrowth in PC12 cells through MAPK/ERK- and PKC-dependent pathways. |
| PubMed: | Evaluation in vitro of synthetic curcumins as agents promoting monocytic gene expression related to β-amyloid clearance. |
| PubMed: | Curcuminoid analogs inhibit nitric oxide production from LPS-activated microglial cells. |
| PubMed: | Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice. |
| PubMed: | [Bioactivity and action modes of bisdemethoxycurcumin against Tetranychus cinnabarinus Bois. (Acari:Tetranychidae)]. |
| PubMed: | The hypomethylation agent bisdemethoxycurcumin acts on the WIF-1 promoter, inhibits the canonical Wnt pathway and induces apoptosis in human non-small-cell lung cancer. |
| PubMed: | Metabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometry. |
| PubMed: | Qualitative and quantitative analysis of curcuminoids in herbal medicines derived from Curcuma species. |
| PubMed: | A comparative study of curcuminoids to measure their effect on inflammatory and apoptotic gene expression in an Aβ plus ibotenic acid-infused rat model of Alzheimer's disease. |
| PubMed: | Hypomethylation effects of curcumin, demethoxycurcumin and bisdemethoxycurcumin on WIF-1 promoter in non-small cell lung cancer cell lines. |
| PubMed: | Physiological and therapeutical roles of ginger and turmeric on endocrine functions. |
| PubMed: | Comparative absorption of a standardized curcuminoid mixture and its lecithin formulation. |
| PubMed: | A screening of curcumin derivatives for antibacterial phototoxic effects studies on curcumin and curcuminoids. XLIII. |
| PubMed: | MGAT3 mRNA: a biomarker for prognosis and therapy of Alzheimer's disease by vitamin D and curcuminoids. |
| PubMed: | Bisdemethoxycurcumin protects endothelial cells against t-BHP-induced cell damage by regulating the phosphorylation level of ERK1/2 and Akt. |
| PubMed: | Anti-inflammatory mechanisms of compounds from Curcuma mangga rhizomes using RAW264.7 macrophage cells. |
| PubMed: | Structural basis for the one-pot formation of the diarylheptanoid scaffold by curcuminoid synthase from Oryza sativa. |
| PubMed: | Curcuminoids rescue long-term potentiation impaired by amyloid peptide in rat hippocampal slices. |
| PubMed: | Studies on curcumin and curcuminoids. XXXIX. Photophysical properties of bisdemethoxycurcumin. |
| PubMed: | The inhibitory effects of different curcuminoids on β-amyloid protein, β-amyloid precursor protein and β-site amyloid precursor protein cleaving enzyme 1 in swAPP HEK293 cells. |
| PubMed: | Suppression of TGF-β1/SMAD pathway and extracellular matrix production in primary keloid fibroblasts by curcuminoids: its potential therapeutic use in the chemoprevention of keloid. |
| PubMed: | Expression, purification and crystallization of a plant type III polyketide synthase that produces diarylheptanoids. |
| PubMed: | Isoxazole analogs of curcuminoids with highly potent multidrug-resistant antimycobacterial activity. |
| PubMed: | The inhibitory effect of turmeric curcuminoids on matrix metalloproteinase-3 secretion in human invasive breast carcinoma cells. |
| PubMed: | Curcuminoids enhance memory in an amyloid-infused rat model of Alzheimer's disease. |
| PubMed: | Effects of Curcuma extracts and curcuminoids on expression of P-glycoprotein and cytochrome P450 3A4 in the intestinal cell culture model LS180. |
| PubMed: | Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa. |
| PubMed: | Up-regulation of heme oxygenase-1 expression through CaMKII-ERK1/2-Nrf2 signaling mediates the anti-inflammatory effect of bisdemethoxycurcumin in LPS-stimulated macrophages. |
| PubMed: | [Chemical constituents from Piper longum]. |
| PubMed: | Inhibitory effects of curcuminoids on passive cutaneous anaphylaxis reaction and scratching behavior in mice. |
| PubMed: | Binding of curcumin with glyoxalase I: Molecular docking, molecular dynamics simulations, and kinetics analysis. |
| PubMed: | Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species. |
| PubMed: | Effects of Curcuma spp. on P-glycoprotein function. |
| PubMed: | Comparison of extraction methods for the analysis of natural dyes in historical textiles by high-performance liquid chromatography. |
| PubMed: | Safety and toxicological evaluation of demethylatedcurcuminoids; a novel standardized curcumin product. |
| PubMed: | Optimized turmeric extracts have potent anti-amyloidogenic effects. |
| PubMed: | Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: probing the active site of the enzyme with molecular modeling and site-directed mutagenesis. |
| PubMed: | Identification and characterization of multiple curcumin synthases from the herb Curcuma longa. |
| PubMed: | Anti-inflammatory properties of curcumin, a major constituent of Curcuma longa: a review of preclinical and clinical research. |
| PubMed: | Direct analysis of curcumin in turmeric by DART-MS. |
| PubMed: | 1alpha,25-dihydroxyvitamin D3 interacts with curcuminoids to stimulate amyloid-beta clearance by macrophages of Alzheimer's disease patients. |
| PubMed: | Demethoxycurcumin induces Bcl-2 mediated G2/M arrest and apoptosis in human glioma U87 cells. |
| PubMed: | Metabolite analysis in Curcuma domestica using various GC-MS and LC-MS separation and detection techniques. |
| PubMed: | Immune blood biomarkers of Alzheimer disease patients. |
| PubMed: | A simple HPLC-fluorescence method for quantitation of curcuminoids and its application to turmeric products. |
| PubMed: | [Study on stability of curcumine, demethoxycurcumin and bisdemethoxycurcumin]. |
| PubMed: | Comparative antiulcer effect of bisdemethoxycurcumin and curcumin in a gastric ulcer model system. |
| PubMed: | Immune defects in Alzheimer's disease: new medications development. |
| PubMed: | Natural derivatives of curcumin attenuate the Wnt/beta-catenin pathway through down-regulation of the transcriptional coactivator p300. |
| PubMed: | Differential solubility of curcuminoids in serum and albumin solutions: implications for analytical and therapeutic applications. |
| PubMed: | Standardization of the ayurvedic formulation Haridra Khanda using high-performance thin-layer chromatography-densitometry. |
| PubMed: | Inhibitory effect of curcuminoids on acetylcholinesterase activity and attenuation of scopolamine-induced amnesia may explain medicinal use of turmeric in Alzheimer's disease. |
| PubMed: | Comparison of inhibitory potency of three different curcuminoid pigments on nitric oxide and tumor necrosis factor production of rat primary microglia induced by lipopolysaccharide. |
| PubMed: | Purification of curcumin, demethoxycurcumin, and bisdemethoxycurcumin by high-speed countercurrent chromatography. |
| PubMed: | Quantitation of curcuminoids in curcuma rhizome by near-infrared spectroscopic analysis. |
| PubMed: | Production of curcuminoids by Escherichia coli carrying an artificial biosynthesis pathway. |
| PubMed: | Neuroprotective and antiinflammatory properties of a novel demethylated curcuminoid. |
| PubMed: | Qualitative and quantitative analysis of four species of Curcuma rhizomes using twice development thin layer chromatography. |
| PubMed: | Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit cancer cell invasion through the down-regulation of MMPs and uPA. |
| PubMed: | Curcuminoids inhibit multiple human cytochromes P450, UDP-glucuronosyltransferase, and sulfotransferase enzymes, whereas piperine is a relatively selective CYP3A4 inhibitor. |
| PubMed: | Comparison of suppressive effects of demethoxycurcumin and bisdemethoxycurcumin on expressions of inflammatory mediators in vitro and in vivo. |
| PubMed: | Molecularly imprinted poly (methacrylamide-co-methacrylic acid) composite membranes for recognition of curcumin. |
| PubMed: | Effect of pure curcumin, demethoxycurcumin, and bisdemethoxycurcumin on WT1 gene expression in leukemic cell lines. |
| PubMed: | In vitro synthesis of curcuminoids by type III polyketide synthase from Oryza sativa. |
| PubMed: | Separation and free radical-scavenging activity of major curcuminoids of Curcuma longa using HPTLC-DPPH method. |
| PubMed: | Curcuminoids-cellular uptake by human primary colon cancer cells as quantitated by a sensitive HPLC assay and its relation with the inhibition of proliferation and apoptosis. |
| PubMed: | Innate immunity and transcription of MGAT-III and Toll-like receptors in Alzheimer's disease patients are improved by bisdemethoxycurcumin. |
| PubMed: | Curcumin, demethoxycurcumin, bisdemethoxycurcumin, tetrahydrocurcumin and turmerones differentially regulate anti-inflammatory and anti-proliferative responses through a ROS-independent mechanism. |
| PubMed: | Formulation and characterization of curcuminoids loaded solid lipid nanoparticles. |
| PubMed: | Curcuminoids, curcumin, and demethoxycurcumin reduce lead-induced memory deficits in male Wistar rats. |
| PubMed: | Comparative antioxidant activities of curcumin and its demethoxy and hydrogenated derivatives. |
| PubMed: | Biological evaluation of curcumin and related diarylheptanoids. |
| PubMed: | Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemopreventive agent curcumin. |
| PubMed: | [Effect of three different curcumin pigmens on the prdiferation of vascular smooth muscle cells by ox-LDL and the expression of LDL-R]. |
| PubMed: | Use of liquid chromatography-electrospray ionization tandem mass spectrometry to identify diarylheptanoids in turmeric (Curcuma longa L.) rhizome. |
| PubMed: | Alpha-glucosidase inhibition of natural curcuminoids and curcumin analogs. |
| PubMed: | Curcuma longa L. constituents inhibit sortase A and Staphylococcus aureus cell adhesion to fibronectin. |
| PubMed: | Effects of naturally occurring compounds on fibril formation and oxidative stress of beta-amyloid. |
| PubMed: | A labdane diterpene glucoside from the rhizomes of Curcuma mangga. |
| PubMed: | The effect of turmeric extracts on inflammatory mediator production. |
| PubMed: | Application of capillary zone electrophoresis in the separation and determination of the curcuminoids in urine. |
| PubMed: | Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of alpha,beta-unsaturated carbonyl compounds. |
| PubMed: | Hypoglycemic effects of turmeric (Curcuma longa L. rhizomes) on genetically diabetic KK-Ay mice. |
| PubMed: | Curcuminoids and sesquiterpenoids in turmeric (Curcuma longa L.) suppress an increase in blood glucose level in type 2 diabetic KK-Ay mice. |
| PubMed: | Chemoprevention of colon cancer by a synthetic curcumin analog involves amelioration of oxidative stress. |
| PubMed: | Anti-allergic principles from Thai zedoary: structural requirements of curcuminoids for inhibition of degranulation and effect on the release of TNF-alpha and IL-4 in RBL-2H3 cells. |
| PubMed: | Inhibitory activity of diarylheptanoids on farnesyl protein transferase. |
| PubMed: | Modulation of human multidrug-resistance MDR-1 gene by natural curcuminoids. |
| PubMed: | Extraction of essential oil and pigments from Curcuma longa [L] by steam distillation and extraction with volatile solvents. |
| PubMed: | Inhibitory effect of curcumin and its natural analogues on genotoxicity of heterocyclic amines from cooked food. |
| PubMed: | Anticarcinogenic effect of bis-1,7-(2-hydroxyphenyl)-hepta-1,6-diene-3,5-dione a curcumin analog on DMH-induced colon cancer model. |
| PubMed: | Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer's disease. |
| PubMed: | Improved HPLC method for the determination of curcumin, demethoxycurcumin, and bisdemethoxycurcumin. |
| PubMed: | Diarylheptanoids with free radical scavenging and hepatoprotective activity in vitro from Curcuma longa. |
| PubMed: | Dietary curcuminoids prevent high-fat diet-induced lipid accumulation in rat liver and epididymal adipose tissue. |
| PubMed: | Antifungal activity of Curcuma longa grown in Thailand. |
| PubMed: | Curcuminoids from Curcuma longa L. (Zingiberaceae) that protect PC12 rat pheochromocytoma and normal human umbilical vein endothelial cells from betaA(1-42) insult. |
| PubMed: | Occurrence of orally administered curcuminoid as glucuronide and glucuronide/sulfate conjugates in rat plasma. |
| PubMed: | Cytotoxicity, antioxidant and anti-inflammatory activities of curcumins I-III from Curcuma longa. |
| PubMed: | Choleretic effects of curcuminoids on an acute cyclosporin-induced cholestasis in the rat. |
| PubMed: | Pro-oxidant, anti-oxidant and cleavage activities on DNA of curcumin and its derivatives demethoxycurcumin and bisdemethoxycurcumin. |
| PubMed: | Cytotoxicity of curcuminoids and some novel compounds from Curcuma zedoaria. |
| PubMed: | Inhibitory effect of curcuminoids on MCF-7 cell proliferation and structure-activity relationships. |
| PubMed: | Inhibitory effects of curcumin on tumorigenesis in mice. |
| PubMed: | Nitric oxide scavenging by curcuminoids. |
| PubMed: | Free radical scavenging activity of curcuminoids. |
| PubMed: | Effects of curcumin, demethoxycurcumin, bisdemethoxycurcumin and tetrahydrocurcumin on 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion. |
| PubMed: | Effects of curcumin on the formation of benzo[a]pyrene derived DNA adducts in vitro. |
| PubMed: | Curcuminoids as potent inhibitors of lipid peroxidation. |
| PubMed: | Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice. |
| PubMed: | Nematocidal activity of turmeric: synergistic action of curcuminoids. |