(13S)-labd-14-ene-8,13-diol, 4630-08-4

Articles:

PubMed:	Sclareol induces plant resistance to root-knot nematode partially through ethylene-dependent enhancement of lignin accumulation.
PubMed:	Synthesis of the Putative Structure of 15-Oxopuupehenoic Acid.
PubMed:	Labdane diterpenoids from Salvia reuterana.
PubMed:	A short synthetic route towards merosesquiterpenes with a benzoxanthene skeleton.
PubMed:	Essential oil composition, antioxidant and antifungal activities of Salvia sclarea L. from Munzur Valley in Tunceli, Turkey.
PubMed:	Characterization of two genes for the biosynthesis of abietane-type diterpenes in rosemary (Rosmarinus officinalis) glandular trichomes.
PubMed:	[Engineering Saccharomyces cerevisiae for sclareol production].
PubMed:	[Preface for special issue on synthetic biology (2013)].
PubMed:	Sclareol reduces CD4+ CD25+ FoxP3+ Treg cells in a breast cancer model in vivo.
PubMed:	Hh signaling inhibitors from Vitex negundo; naturally occurring inhibitors of the GLI1-DNA complex.
PubMed:	Chemical composition and anticancer activity of essential oils of Mediterranean sage (Salvia officinalis L.) grown in different environmental conditions.
PubMed:	Extracellular localization of the diterpene sclareol in clary sage (Salvia sclarea L., Lamiaceae).
PubMed:	Bioactive constituents of Salvia chrysophylla Stapf.
PubMed:	Toward a biosynthetic route to sclareol and amber odorants.
PubMed:	Enzymatic biotransformation of terpenes as bioactive agents.
PubMed:	A diterpene synthase from the clary sage Salvia sclarea catalyzes the cyclization of geranylgeranyl diphosphate to (8R)-hydroxy-copalyl diphosphate.
PubMed:	Cancer cell spheroids as a model to evaluate chemotherapy protocols.
PubMed:	Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea (L.) and their relevance for perfume manufacture.
PubMed:	Identification of natural diterpenes that inhibit bacterial wilt disease in tobacco, tomato and Arabidopsis.
PubMed:	Sclareol exhibits anti-inflammatory activity in both lipopolysaccharide-stimulated macrophages and the λ-carrageenan-induced paw edema model.
PubMed:	Antimicrobial evaluation of diterpenes from Copaifera langsdorffii oleoresin against periodontal anaerobic bacteria.
PubMed:	First enantiospecific synthesis of marine sesquiterpene quinol akaol A.
PubMed:	Four potato (Solanum tuberosum) ABCG transporters and their expression in response to abiotic factors and Phytophthora infestans infection.
PubMed:	Synthesis of the scalarane sesterterpenoid 16-deacetoxy-12-epi-scalarafuranacetate.
PubMed:	The labdane diterpene sclareol (labd-14-ene-8, 13-diol) induces apoptosis in human tumor cell lines and suppression of tumor growth in vivo via a p53-independent mechanism of action.
PubMed:	Isolation, chemical, and biotransformation routes of labdane-type diterpenes.
PubMed:	Chemical composition and antimicrobial activity of the essential oils from Cleome spinosa.
PubMed:	Sclareol modulates the Treg intra-tumoral infiltrated cell and inhibits tumor growth in vivo.
PubMed:	Mitochondria-targeted liposomes improve the apoptotic and cytotoxic action of sclareol.
PubMed:	Hemisynthesis of two marine cheilanthane sesterterpenes from (-)-sclareol: first enantioselective synthesis of petrosaspongiolide R.
PubMed:	Fragrance material review on sclareol.
PubMed:	Diversity of essential oil glands of clary sage (Salvia sclarea L., Lamiaceae).
PubMed:	Microbial hydroxylation of sclareol by Rhizopus stolonifer.
PubMed:	Cell growth inhibitory action of an unusual labdane diterpene, 13-epi-sclareol in breast and uterine cancers in vitro.
PubMed:	Antibacterial and cytotoxic activity of the acetone extract of the flowers of Salvia sclarea and some natural products.
PubMed:	Diels-Alder cycloaddition approach to puupehenone-related metabolites: synthesis of the potent angiogenesis inhibitor 8-epipuupehedione.
PubMed:	Liposomes modify the subcellular distribution of sclareol uptake by HCT-116 cancer cell lines.
PubMed:	Sclareol induces apoptosis in human HCT116 colon cancer cells in vitro and suppression of HCT116 tumor growth in immunodeficient mice.
PubMed:	Structure elucidation and antibacterial activity of new fungal metabolites of sclareol.
PubMed:	Calorimetric study on the induction of interdigitated phase in hydrated DPPC bilayers by bioactive labdanes and correlation to their liposome stability: The role of chemical structure.
PubMed:	Hemisynthesis of new labdane derivatives from (-)-sclareol.
PubMed:	Synthesis of ent-thallusin.
PubMed:	A new route toward 7-Oxo-13-hydroxy-8,11,13-podocarpatrienes from labdane diterpenes.
PubMed:	Labd-14-ene-8,13-diol (sclareol) induces cell cycle arrest and apoptosis in human breast cancer cells and enhances the activity of anticancer drugs.
PubMed:	Cytotoxic and antitumor activity of liposome-incorporated sclareol against cancer cell lines and human colon cancer xenografts.
PubMed:	NpPDR1, a pleiotropic drug resistance-type ATP-binding cassette transporter from Nicotiana plumbaginifolia, plays a major role in plant pathogen defense.
PubMed:	First enantiospecific synthesis of the antitumor marine sponge metabolite (-)-15-oxopuupehenol from (-)-sclareol.
PubMed:	A comparative study of the effects of cholesterol and sclareol, a bioactive labdane type diterpene, on phospholipid bilayers.
PubMed:	Effect of 13-epi-sclareol on the bacterial respiratory chain.
PubMed:	Pathogen-responsive expression of a putative ATP-binding cassette transporter gene conferring resistance to the diterpenoid sclareol is regulated by multiple defense signaling pathways in Arabidopsis.
PubMed:	Identification of regulatory sequence elements within the transcription promoter region of NpABC1, a gene encoding a plant ABC transporter induced by diterpenes.
PubMed:	Antibacterial diterpenoids from Astragalus brachystachys.
PubMed:	The plant PDR family of ABC transporters.
PubMed:	Molecular basis of pimarane compounds as novel activators of large-conductance Ca(2+)-activated K(+) channel alpha-subunit.
PubMed:	The ABC transporter SpTUR2 confers resistance to the antifungal diterpene sclareol.
PubMed:	Chromatographic (GC-MS, HPLC) and virological evaluations of Salvia sclarea infected by BBWV-I.
PubMed:	A plant plasma membrane ATP binding cassette-type transporter is involved in antifungal terpenoid secretion.
PubMed:	Labdane type diterpenes down-regulate the expression of c-Myc protein, but not of Bcl-2, in human leukemia T-cells undergoing apoptosis.
PubMed:	Biotransformation of two cytotoxic terpenes, alpha-santonin and sclareol by Botrytis cinerea.
PubMed:	Potential nitrite scavengers as inhibitors of the formation of N-nitrosamines in solution and tobacco matrix systems.
PubMed:	Synthesis of 11,12-epoxydrim-8,12-en-11-ol, 11,12-diacetoxydrimane, and warburganal from (-)-sclareol.
PubMed:	Synthesis and antitumoral activities of marine ent-chromazonarol and related compounds.
PubMed:	Chemical analysis and antimicrobial activity of the resin Ladano, of its essential oil and of the isolated compounds.
PubMed:	The effect of sclareol on growth and cell cycle progression of human leukemic cell lines.
PubMed:	A concise synthesis and in vitro cytotoxicity of new labdane diterpenes.
PubMed:	A concise conversion of (-)-sclareol into (+)-coronarin E and (-)-7-epi-coronarin A
PubMed:	[Plant anatomical and phytochemical evaluation of Salvia species].
PubMed:	Biorationals fromNicotiana protect cucumbers againstColletotrichum lagenarium (Pass.) ell. & halst disease development.
PubMed:	Terpenoids from Salvia sclarea.
PubMed:	Synthesis of manool-related labdane diterpenes as platelet aggregation inhibitors.
PubMed:	Identification of four biliary metabolites of the diterpene sclareol in the laboratory rat.
PubMed:	Leaf surface chemicals fromNicotiana affecting germination ofPeronospora tabacina (adam) sporangia.
PubMed:	Hydroxylation and glucoside conjugation in the microbial metabolism of the diterpene sclareol.
PubMed:	Microbial models of mammalian metabolism: fungal metabolism of the diterpene sclareol by Cunninghamella species.
PubMed:	Influences of diterpene sclareol glycol on some dopamine related behavior.
PubMed:	The effects of the diterpene sclareol glycol on seizures do not depend on central benzodiazepine receptors.
PubMed:	The response of diterpene sclareol glycol to acute hypoxia in mice.
PubMed:	[The effect of sclareol lactone and sclareol glycol on artificially induced lung metastases of Lewis lung carcinoma (a preliminary report)].
PubMed:	Measures of anxiety, retention and stress in the rat following treatment with the diterpene sclareol glycol.
PubMed:	Diterpene sclareol glycol inhibits clonidine-induced aggressive responses in mice.
PubMed:	Effects of the diterpene sclareol glycol on convulsive seizures.
PubMed:	Effects of the diterpene sclareol glycol on body temperature in rats.
PubMed:	[Study of the effect of sclareol glycol diterpene on the release of adenohypophysial hormones prolactin, somatotropin and adenocorticotrophic hormone].
PubMed:	[Study of the effect of sclareol glycol diterpene on the 3',5'-AMP level].
PubMed:	Experimental study of essential oils from two varieties of cultivated thyme, sesquiterpene Germacron and diterpene Sclareol for cholagogic and choleretic activity.
PubMed:	[Effect of diterpene sklareol glycol on the conflict test and its correlation with diazepam].
PubMed:	[Effects of sklareol-glycol on pentylenetetrazole-induced convulsions and its interaction with diazepam].
PubMed:	BIOSYNTHESIS AND METABOLISM OF (14C)SCLAREOL.
PubMed:	Biosynthesis of sclareol, beta-sitosterol, and oleanolic acid from mevalonic acid-2-C-14.
PubMed:	Biosynthesis of 14C-sclareol and beta-sitosterol from 2-14C-mevalonic acid.
PubMed:	[Sclareol, its chemical constitution and use in the synthesis of aromatic principles of amber; a review].
PubMed:	[Not Available].