garcinol, 78824-30-3

Articles:

PubMed:	Garcinol, an acetyltransferase inhibitor, suppresses proliferation of breast cancer cell line MCF-7 promoted by 17β-estradiol.
PubMed:	Garcinol suppresses inflammation-associated colon carcinogenesis in mice.
PubMed:	High-throughput screen of natural product libraries for hsp90 inhibitors.
PubMed:	Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo.
PubMed:	Protective effects of garcinol in mice with lipopolysaccharide/D-galactosamine-induced apoptotic liver injury.
PubMed:	Induction of p21(Waf1/Cip1) by garcinol via downregulation of p38-MAPK signaling in p53-independent H1299 lung cancer.
PubMed:	Chromatin-regulating proteins as targets for cancer therapy.
PubMed:	Direct interaction of garcinol and related polyisoprenylated benzophenones of Garcinia cambogia fruits with the transcription factor STAT-1 as a likely mechanism of their inhibitory effect on cytokine signaling pathways.
PubMed:	A cell-free fluorometric high-throughput screen for inhibitors of Rtt109-catalyzed histone acetylation.
PubMed:	Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma.
PubMed:	Lysine acetyltransferase PCAF is a key regulator of arteriogenesis.
PubMed:	Histone modifications of Notch1 promoter affect lung CD4+ T cell differentiation in asthmatic rats.
PubMed:	Histone acetylation regulates osteodifferentiation of hDPSCs via DSPP.
PubMed:	Emerging antineoplastic effects of garcinol besides role in inhibiting growth in pancreatic carcinomas.
PubMed:	Lysosome-dependent p300/FOXP3 degradation and limits Treg cell functions and enhances targeted therapy against cancers.
PubMed:	[Expressions of reactive oxygen species and fibronectin are regulated by transcriptional co-activator p300 in human mesangial cells exposed to high glucose and methylglyoxal advanced glycation end products].
PubMed:	Epigenetic regulation of extracellular-superoxide dismutase in human monocytes.
PubMed:	p300/CBP dependent hyperacetylation of histone potentiates anticancer activity of gefitinib nanoparticles.
PubMed:	Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells.
PubMed:	A naturally-occurring histone acetyltransferase inhibitor derived from Garcinia indica impairs newly acquired and reactivated fear memories.
PubMed:	Garcinol sensitizes human pancreatic adenocarcinoma cells to gemcitabine in association with microRNA signatures.
PubMed:	The inhibitory effect of pterostilbene on inflammatory responses during the interaction of 3T3-L1 adipocytes and RAW 264.7 macrophages.
PubMed:	Chemoprevention of 7,12-dimethylbenz[a]anthracene (DMBA)-induced hamster cheek pouch carcinogenesis by a 5-lipoxygenase inhibitor, garcinol.
PubMed:	Acetylation-mediated suppression of transcription-independent memory: bidirectional modulation of memory by acetylation.
PubMed:	Radiation-induced human endogenous retrovirus (HERV)-R env gene expression by epigenetic control.
PubMed:	Activation of tachykinin, neurokinin 3 receptors affects chromatin structure and gene expression by means of histone acetylation.
PubMed:	Anticancer action of garcinol in vitro and in vivo is in part mediated through inhibition of STAT-3 signaling.
PubMed:	Cancer chemoprevention and nutriepigenetics: state of the art and future challenges.
PubMed:	Garcinol regulates EMT and Wnt signaling pathways in vitro and in vivo, leading to anticancer activity against breast cancer cells.
PubMed:	Potential role of garcinol as an anticancer agent.
PubMed:	Synergistic effect of garcinol and curcumin on antiproliferative and apoptotic activity in pancreatic cancer cells.
PubMed:	Acetylation of retinal histones in diabetes increases inflammatory proteins: effects of minocycline and manipulation of histone acetyltransferase (HAT) and histone deacetylase (HDAC).
PubMed:	Garcinol, a histone acetyltransferase inhibitor, radiosensitizes cancer cells by inhibiting non-homologous end joining.
PubMed:	Hippocampal histone acetylation regulates object recognition and the estradiol-induced enhancement of object recognition.
PubMed:	Inhibitory effects of garcinol and pterostilbene on cell proliferation and adipogenesis in 3T3-L1 cells.
PubMed:	Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase.
PubMed:	Garcinol inhibits cell growth in hepatocellular carcinoma Hep3B cells through induction of ROS-dependent apoptosis.
PubMed:	Cambogin is preferentially cytotoxic to cells expressing PDGFR.
PubMed:	Garcinol-induced apoptosis in prostate and pancreatic cancer cells is mediated by NF- kappaB signaling.
PubMed:	Garcinol inhibits cell proliferation and promotes apoptosis in pancreatic adenocarcinoma cells.
PubMed:	Nicotinic acetylcholine receptor-based blockade: applications of molecular targets for cancer therapy.
PubMed:	Epigenetic control of tissue-type plasminogen activator synthesis in human endothelial cells.
PubMed:	Cigarette smoke extract regulates cytosolic phospholipase A2 expression via NADPH oxidase/MAPKs/AP-1 and p300 in human tracheal smooth muscle cells.
PubMed:	Garcinol promotes neurogenesis in rat cortical progenitor cells through the duration of extracellular signal-regulated kinase signaling.
PubMed:	Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements.
PubMed:	Cancer chemoprevention by targeting the epigenome.
PubMed:	Analysis of the molecular and regulatory properties of active porcine endogenous retrovirus gamma-1 long terminal repeats in kidney tissues of the NIH-Miniature pig.
PubMed:	Fluorinated 2'-hydroxychalcones as garcinol analogs with enhanced antioxidant and anticancer activities.
PubMed:	Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host.
PubMed:	Prostacyclin receptor suppresses cardiac fibrosis: role of CREB phosphorylation.
PubMed:	Garcinol potentiates TRAIL-induced apoptosis through modulation of death receptors and antiapoptotic proteins.
PubMed:	Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins.
PubMed:	Apoptosis-inducing effect of garcinol is mediated by NF-kappaB signaling in breast cancer cells.
PubMed:	Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription.
PubMed:	Effects of garcinol and guttiferone K isolated from Garcinia cambogia on oxidative/nitrative modifications in blood platelets and plasma.
PubMed:	Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs.
PubMed:	Cigarette smoke extract induces COX-2 expression via a PKCalpha/c-Src/EGFR, PDGFR/PI3K/Akt/NF-kappaB pathway and p300 in tracheal smooth muscle cells.
PubMed:	Chicken HS4 insulator significantly improves baculovirus-mediated foreign gene expression in insect cells by modifying the structure of neighbouring chromatin in virus minichromosome.
PubMed:	Identification of 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 as functional targets of the anti-inflammatory and anti-carcinogenic garcinol.
PubMed:	High-performance liquid chromatography and LC-ESI-MS method for identification and quantification of two isomeric polyisoprenylated benzophenones isoxanthochymol and camboginol in different extracts of Garcinia species.
PubMed:	Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells.
PubMed:	Synthesis of benzamide derivatives of anacardic acid and their cytotoxic activity.
PubMed:	Bioassay-guided isolation of xanthones and polycyclic prenylated acylphloroglucinols from Garcinia oblongifolia.
PubMed:	Mechanism of p300 specific histone acetyltransferase inhibition by small molecules.
PubMed:	Bioassay and ultraperformance liquid chromatography/mass spectrometry guided isolation of apoptosis-inducing benzophenones and xanthone from the pericarp of Garcinia yunnanensis Hu.
PubMed:	Acetylation: a novel method for modulation of the immune response following trauma/hemorrhage and inflammatory second hit in animals and humans.
PubMed:	Polyisoprenylated benzophenones and an unusual polyisoprenylated tetracyclic xanthone from the fruits of Garcinia cambogia.
PubMed:	Leishmanicidal and cholinesterase inhibiting activities of phenolic compounds from Allanblackia monticola and Symphonia globulifera.
PubMed:	Autoacetylation induced specific structural changes in histone acetyltransferase domain of p300: probed by surface enhanced Raman spectroscopy.
PubMed:	Inhibition of human lipoprotein oxidation by morelloflavone and camboginol from Garcinia dulcis.
PubMed:	Specific inhibition of p300-HAT alters global gene expression and represses HIV replication.
PubMed:	Selective inhibition of CBP/p300 HAT.
PubMed:	Liquid chromatography-tandem mass spectrometry method for identification and quantification of two biologically active polyisoprenylated benzophenones, isoxanthochymol and camboginol, in Garcinia species.
PubMed:	Effects of garcinol and its derivatives on intestinal cell growth: Inhibitory effects and autoxidation-dependent growth-stimulatory effects.
PubMed:	A rapid liquid chromatography-tandem mass spectrometry method for quantification of a biologically active molecule camboginol in the extract of Garcinia cambogia.
PubMed:	Oblongifolins A-D, polyprenylated benzoylphloroglucinol derivatives from Garcinia oblongifolia.
PubMed:	Modulation of arachidonic acid metabolism and nitric oxide synthesis by garcinol and its derivatives.
PubMed:	Garcinol modulates tyrosine phosphorylation of FAK and subsequently induces apoptosis through down-regulation of Src, ERK, and Akt survival signaling in human colon cancer cells.
PubMed:	Dietary garcinol inhibits 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in rats.
PubMed:	Antimicrobial effects of antioxidants with and without clarithromycin on Helicobacter pylori.
PubMed:	A polyisoprenylated ketone from Calophyllum enervosum.
PubMed:	Effects of garcinol on free radical generation and NO production in embryonic rat cortical neurons and astrocytes.
PubMed:	An antibacterial biphenyl derivative from Garcinia bancana MIQ.
PubMed:	Inhibition of cell proliferation by nobiletin, a dietary phytochemical, associated with apoptosis and characteristic gene expression, but lack of effect on early rat hepatocarcinogenesis in vivo.
PubMed:	Suppression of inducible nitric oxide synthase and cyclooxygenase-2 in downregulating nuclear factor-kappa B pathway by Garcinol.
PubMed:	Polyisoprenylated benzophenone, garcinol, a natural histone acetyltransferase inhibitor, represses chromatin transcription and alters global gene expression.
PubMed:	Rapid analysis of gene expression changes caused by liver carcinogens and chemopreventive agents using a newly developed three-dimensional microarray system.
PubMed:	Cytotoxic benzophenone derivatives from Garcinia species display a strong apoptosis-inducing effect against human leukemia cell lines.
PubMed:	The bactericidal effects of Lactobacillus acidophilus, garcinol and Protykin compared to clarithromycin, on Helicobacter pylori.
PubMed:	Polyprenylated benzophenones from Garcinia assigu and their potential cancer chemopreventive activities.
PubMed:	Induction of apoptosis by garcinol and curcumin through cytochrome c release and activation of caspases in human leukemia HL-60 cells.
PubMed:	Free radical scavenging activity and antiulcer activity of garcinol from Garcinia indica fruit rind.
PubMed:	Prevention of colonic aberrant crypt foci by dietary feeding of garcinol in male F344 rats.
PubMed:	Antioxidative and anti-glycation activity of garcinol from Garcinia indica fruit rind.
PubMed:	Guttiferone F, the first prenylated benzophenone from Allanblackia stuhlmannii.
PubMed:	Antibacterial activity of some Garcinia benzophenone derivatives against methicillin-resistant Staphylococcus aureus.
PubMed:	Structure and chemotherapeutical activity of a polyisoprenylated benzophenone from the stem bark of Garcinia huillensis.