3-hydroxyaspartic acid, 1860-87-3

Articles:

PubMed:	Isolation and structures of pipecolidepsins A and B, cytotoxic cyclic depsipeptides from the Madagascan sponge Homophymia lamellosa.
PubMed:	An acute glutamate exposure induces long-term down regulation of GLAST/EAAT1 uptake activity in cultured Bergmann glia cells.
PubMed:	The SLC1 high-affinity glutamate and neutral amino acid transporter family.
PubMed:	Astrocytes release D-serine by a large vesicle.
PubMed:	Antinociceptive effect of rat D-serine racemase inhibitors, L-serine-O-sulfate, and L-erythro-3-hydroxyaspartate in an arthritic pain model.
PubMed:	A practical synthesis of N α-Fmoc protected L-threo-β-hydroxyaspartic acid derivatives for coupling via α- or β-carboxylic group.
PubMed:	Neuroprotective effect of CPDT on THA-induced cortical motor neuron death in an organotypic culture model.
PubMed:	Insights into the mechanism of Pseudomonas dacunhae aspartate beta-decarboxylase from rapid-scanning stopped-flow kinetics.
PubMed:	Neuroprotective effect of erythropoietin in amyotrophic lateral sclerosis (ALS) model in vitro. Ultrastructural study.
PubMed:	Characterization of chronic glutamate-mediated motor neuron toxicity in organotypic spinal cord culture prepared from ALS model mice.
PubMed:	Neuroprotective effects of yokukansan, a traditional Japanese medicine, on glutamate-mediated excitotoxicity in cultured cells.
PubMed:	Iron is a potential key mediator of glutamate excitotoxicity in spinal cord motor neurons.
PubMed:	gamma-Glutamate and beta-hydroxyaspartate in proteins.
PubMed:	Glutamate transporters of blood platelets as potential peripheral markers to analyze changes of glutamate transport activity in brain under altered gravity conditions.
PubMed:	Huperzine A provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death.
PubMed:	Non-heme hydroxylase engineering for simple enzymatic synthesis of L-threo-hydroxyaspartic acid.
PubMed:	Genome-scale analysis of anti-metabolite directed strain engineering.
PubMed:	A concise, asymmetric synthesis of (2R,3R)-3-hydroxyaspartic acid.
PubMed:	Tryptophan breakdown pathway in bipolar mania.
PubMed:	[Modulating effect of glutamate transporter inhibitors on accumulation and release of the neuromediator by the brain nerve terminals in rats].
PubMed:	Autophagic degeneration of motor neurons in a model of slow glutamate excitotoxicity in vitro.
PubMed:	Effects of the inhibitors on glutamate uptake by nerve terminals after exposure of rats to centrifuge-induced hypergravity.
PubMed:	Expression of GFP-tagged neuronal glutamate transporters in cerebellar Purkinje neurons.
PubMed:	Structure, conformation and biological activity of a novel lipodepsipeptide from Pseudomonas corrugata: cormycin A.
PubMed:	Protective cap over CA1 synapses: extrasynaptic glutamate does not reach the postsynaptic density.
PubMed:	Activation of protein kinase C reduces GLAST in the plasma membrane of rat Müller cells in primary culture.
PubMed:	Identification of glutamate transporters and receptors in mouse testis.
PubMed:	Glutamate spillover in the striatum depresses dopaminergic transmission by activating group I metabotropic glutamate receptors.
PubMed:	Serine racemase homologue of Saccharomyces cerevisiae has L-threo-3-hydroxyaspartate dehydratase activity.
PubMed:	A novel enzyme, D-3-hydroxyaspartate aldolase from Paracoccus denitrificans IFO 13301: purification, characterization, and gene cloning.
PubMed:	Electrical and pharmacological properties of the slow depolarization induced by Schaffer collateral stimulation in astrocytes of the rat hippocampal CA1 region.
PubMed:	Metabotropic glutamate receptor-mediated hetero-synaptic interaction of red- and green-cone inputs to LHC of carp retina.
PubMed:	Isoflurane preconditioning reduces purkinje cell death in an in vitro model of rat cerebellar ischemia.
PubMed:	Neuronal glutamate uptake Contributes to GABA synthesis and inhibitory synaptic strength.
PubMed:	The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures.
PubMed:	Modulation of glutamatergic transmission by bergmann glial cells in rat cerebellum in situ.
PubMed:	Involvement of acetylated tubulin in the regulation of Na+,K+ -ATPase activity in cultured astrocytes.
PubMed:	Local application of L- threo-hydroxyaspartate and malonate in rats in vivo induces rigidity and damages neurons of the substantia nigra, pars compacta.
PubMed:	Glutamate-induced calcium increase in myotubes depends on up-regulation of a sodium-dependent transporter.
PubMed:	Feeding-induced decrease in extracellular glutamate level in the rat nucleus accumbens: dependence on glutamate uptake.
PubMed:	Beta-amyloid enhances glial glutamate uptake activity and attenuates synaptic efficacy.
PubMed:	Inhibitor of glutamate transport alters synaptic transmission at sensorimotor synapses in Aplysia.
PubMed:	gamma-glutamate and beta-hydroxyaspartate in proteins.
PubMed:	Differing effects of substrate and non-substrate transport inhibitors on glutamate uptake reversal.
PubMed:	Effects of threo-beta-hydroxyaspartate derivatives on excitatory amino acid transporters (EAAT4 and EAAT5).
PubMed:	Hypoglycemia induces general neuronal death, whereas hypoxia and glutamate transport blockade lead to selective retinal ganglion cell death in vitro.
PubMed:	Methylmercury inhibits cysteine uptake in cultured primary astrocytes, but not in neurons.
PubMed:	Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: role of glutamate clearance.
PubMed:	Dopamine-dependent inhibition of glycine release in the nucleus accumbens of the rat brain during food consumption.
PubMed:	A Na+-dependent electrogenic glutamate transporter current in voltage-clamped cells of corpora allata in the cricket Gryllus bimaculatus.
PubMed:	Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase.
PubMed:	Release of D,L-threo-beta-hydroxyaspartate as a false transmitter from excitatory amino acid-releasing nerve terminals.
PubMed:	Regulation of mitochondrial glutamine/glutamate metabolism by glutamate transport: studies with (15)N.
PubMed:	Effects of glial glutamate transporter inhibitors on intracellular Na+ in mouse astrocytes.
PubMed:	Possible linkage between glutamate transporter and mitogen-activated protein kinase cascade in cultured rat cortical astrocytes.
PubMed:	Transient increase in the high affinity [3H]-L-glutamate uptake activity during in vitro development of hippocampal neurons in culture.
PubMed:	Müller cell protection of rat retinal ganglion cells from glutamate and nitric oxide neurotoxicity.
PubMed:	3-Nitropropionic acid neurotoxicity in organotypic striatal and corticostriatal slice cultures is dependent on glucose and glutamate.
PubMed:	Effect of ionotropic glutamate receptors antagonists on the modifications in extracellular glutamate and aspartate levels during picrotoxin seizures: a microdialysis study in freely moving rats.
PubMed:	[Dopamine-dependent inhibition of glycine release in the rat nucleus accumbens during feeding].
PubMed:	Synaptically released glutamate does not overwhelm transporters on hippocampal astrocytes during high-frequency stimulation.
PubMed:	Na+-dependent high-affinity glutamate transport in macrophages.
PubMed:	[Changes in glutamate release in the rat nucleus accumbens during food and pain reinforcement].
PubMed:	Glutamate transport blockade has a differential effect on AMPA and NMDA receptor-mediated synaptic transmission in the developing barrel cortex.
PubMed:	Control of synaptic depression by glutamate transporters.
PubMed:	Transient treatments with L-glutamate and threo-beta-hydroxyaspartate induce swelling of rat cultured astrocytes.
PubMed:	Metabotropic glutamate receptors and blockade of glial Krebs cycle depress glycinergic synaptic currents of mouse hypoglossal motoneurons.
PubMed:	SNARE protein-dependent glutamate release from astrocytes.
PubMed:	Trans-inhibition of glutamate transport prevents excitatory amino acid-induced glycolysis in astrocytes.
PubMed:	Biosynthetic origin of syringomycin and syringopeptin 22, toxic secondary metabolites of the phytopathogenic bacterium Pseudomonas syringae pv. syringae.
PubMed:	Effects of inhibiting glutamine synthetase and blocking glutamate uptake on b-wave generation in the isolated rat retina.
PubMed:	Motor neuron degeneration is attenuated in bax-deficient neurons in vitro.
PubMed:	Characterization of (2S,2'R,3'R)-2-(2',3'-[3H]-dicarboxycyclopropyl)glycine binding in rat brain.
PubMed:	Action of excitatory amino acids on hypodermis and the motornervous system of Ascaris suum: pharmacological evidence for a glutamate transporter.
PubMed:	DL-threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters.
PubMed:	Modulation of human glutamate transporter activity by phorbol ester.
PubMed:	AMPA receptor-mediated slow neuronal death in the rat spinal cord induced by long-term blockade of glutamate transporters with THA.
PubMed:	Postsynaptic glutamate transport at the climbing fiber-Purkinje cell synapse.
PubMed:	Intracerebral microdialysis study of glutamate reuptake in awake, behaving rats.
PubMed:	Glutamatergic enteric neurons.
PubMed:	Transporters buffer synaptically released glutamate on a submillisecond time scale.
PubMed:	Stimulated release of lactate in freely moving rats is dependent on the uptake of glutamate.
PubMed:	Short-lived intermediates in aspartate aminotransferase systems.
PubMed:	Inhibition of glutamate uptake causes an acute increase in aqueous humor protein.
PubMed:	Aspartate aminotransferase complexed with erythro-beta-hydroxyaspartate: crystallographic and spectroscopic identification of the carbinolamine intermediate.
PubMed:	Attenuation of trimethyltin-evoked glutamate (GLU) efflux from rat cortical and hippocampal slices.
PubMed:	Glutamate transport modulation of paracellular permeability across LLC-PK1-F+ monolayers.
PubMed:	The mechanisms controlling physiologically stimulated changes in rat brain glucose and lactate: a microdialysis study.
PubMed:	Autoradiographic studies indicate regional variations in the characteristics of L-glutamate transporters in the rat brain.
PubMed:	Modulation of excitatory synaptic transmission by low concentrations of glutamate in cultured rat hippocampal neurons.
PubMed:	Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures.
PubMed:	Characterization of recombinant human coagulation factor XFriuli.
PubMed:	Noise analysis of the glutamate-activated current in photoreceptors.
PubMed:	Cone photoreceptors respond to their own glutamate release in the tiger salamander.
PubMed:	The glutamate uptake regulatory protein (Grp) of Zymomonas mobilis and its relation to the global regulator Lrp of Escherichia coli.
PubMed:	Reaction of aspartate aminotransferase with L-erythro-3-hydroxyaspartate: involvement of Tyr70 in stabilization of the catalytic intermediates.
PubMed:	Microdialysis as a tool for in vivo investigation of glutamate transport capacity in rat brain.
PubMed:	Effects of a glutamate uptake inhibitor on glutamate release induced by veratridine and ischemia.
PubMed:	Other lipopeptides.
PubMed:	Effects of L-trans-pyrrolidine-2,4-dicarboxylate and L-threo-3-hydroxyaspartate on the binding of [3H]L-aspartate, [3H]alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA), [3H]DL-(E)-2-amino-4-propyl-5-phosphono-3-pentenoate (CGP 39653), [3H]6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and [3H]kainate studied by autoradiography in rat forebrain.
PubMed:	L-glutamate uptake inhibitors may stimulate phosphoinositide hydrolysis in baby hamster kidney cells expressing mGluR1a via heteroexchange with L-glutamate without direct activation of mGluR1a.
PubMed:	Block of glutamate transporters potentiates postsynaptic excitation.
PubMed:	Regional differences in the inhibition of L-glutamate and L-aspartate sodium-dependent high affinity uptake systems in rat CNS synaptosomes by L-trans-pyrrolidine-2,4-dicarboxylate, threo-3-hydroxy-D-aspartate and D-aspartate.
PubMed:	Pre- and post-synaptic modulators of excitatory neurotransmission: comparative effects on hypoxia/hypoglycemia in cortical cultures.
PubMed:	Glial contributions to excitatory neurotransmission in cultured hippocampal cells.
PubMed:	Na(+)-dependent high affinity uptake of L-glutamate in primary cultures of human fibroblasts isolated from three different types of tissue.
PubMed:	The Na(+)-dependent binding of [3H]L-aspartate in thaw-mounted sections of rat forebrain.
PubMed:	Glucose can fuel glutamate uptake in ischemic brain.
PubMed:	Depolarization elicits, while hyperpolarization blocks uptake of endogenous glutamate by retinal horizontal cells of the turtle.
PubMed:	(2S,3S,4R)-2-(carboxycyclopropyl)glycine, a potent and competitive inhibitor of both glial and neuronal uptake of glutamate.
PubMed:	Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity.
PubMed:	Modulatory action of kainic acid on glutamate release from rat brain cortical synaptosomes.
PubMed:	Binding of protein S to C4b-binding protein. Mutagenesis of protein S.
PubMed:	Evidence for the existence of O-linked sugar chains consisting of glucose and xylose in bovine thrombospondin.
PubMed:	Philanthotoxins block glutamatergic transmission in rat hippocampus--I. Reduction of high affinity glutamate uptake demonstrated by light microscopy surface autoradiography.
PubMed:	The pharmacological profile of glutamate-evoked ascorbic acid efflux measured by in vivo electrochemistry.
PubMed:	beta-Hydroxyaspartic acid and beta-hydroxyasparagine residues in recombinant human protein S are not required for anticoagulant cofactor activity or for binding to C4b-binding protein.
PubMed:	Structure-function relationships of epidermal growth factor modules in vitamin K-dependent clotting factors.
PubMed:	Prepeptide sequence of cinnamycin (Ro 09-0198): the first structural gene of a duramycin-type lantibiotic.
PubMed:	Electrogenic uptake of glutamate and aspartate into glial cells isolated from the salamander (Ambystoma) retina.
PubMed:	DL-threo-3-hydroxyaspartate reduces NMDA receptor activation by glutamate in cultured neurons.
PubMed:	Characterization of glutamate uptake systems in astrocyte primary cultures from rat brain.
PubMed:	Anatomical and pharmacological heterogeneity of D-[3H]aspartate binding sites.
PubMed:	Excitatory amino acid pathways in brain-stimulation reward.
PubMed:	Calcium binding to the isolated beta-hydroxyaspartic acid-containing epidermal growth factor-like domain of bovine factor X.
PubMed:	The neurotoxicity of 1-methyl-4-phenylpyridinium in cultured cerebellar granule cells.
PubMed:	Substitution of a lysyl residue for arginine 386 of Escherichia coli aspartate aminotransferase.
PubMed:	Hydroxylation of aspartic acid in domains homologous to the epidermal growth factor precursor is catalyzed by a 2-oxoglutarate-dependent dioxygenase.
PubMed:	Beta-hydroxyaspartic acid in the first epidermal growth factor-like domain of protein C. Its role in Ca2+ binding and biological activity.
PubMed:	The role of beta-hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX.
PubMed:	Potentiation by kainate of excitatory amino acid release in striatum: complementary in vivo and in vitro experiments.
PubMed:	beta-Hydroxyaspartic acid or beta-hydroxyasparagine in bovine low density lipoprotein receptor and in bovine thrombomodulin.
PubMed:	Occurrence of beta-hydroxylated asparagine residues in non-vitamin K-dependent proteins containing epidermal growth factor-like domains.
PubMed:	Continuous glutamate leakage from brain cells is balanced by compensatory high-affinity reuptake transport.
PubMed:	Na+-dependent "binding" of D-aspartate in brain membranes is largely due to uptake into membrane-bounded saccules.
PubMed:	Binding of iron by factor IX. Possible role for beta-hydroxyaspartic acid.
PubMed:	Protein C in bovine plasma after warfarin treatment. Purification, partial characterization, and beta-hydroxyaspartic acid content.
PubMed:	Calcium binding to a human factor IXa derivative lacking gamma-carboxyglutamic acid: evidence for two high-affinity sites that do not involve beta-hydroxyaspartic acid.
PubMed:	Inhibitors of high-affinity uptake augment depolarizations of hippocampal neurons induced by glutamate, kainate and related compounds.
PubMed:	Neurotoxicity of L-glutamate and DL-threo-3-hydroxyaspartate in the rat striatum.
PubMed:	Interaction of aspartate and aspartate-derived antimetabolites with the enzymes of the threonine biosynthetic pathway of Escherichia coli.
PubMed:	Structure and function of protein C.
PubMed:	Beta-hydroxyaspartic acid in vitamin K-dependent plasma proteins from scorbutic and warfarin-treated guinea pigs.
PubMed:	erythro-beta-Hydroxyaspartic acid in bovine factor IX and factor X.
PubMed:	Beta-hydroxyaspartic acid in vitamin K-dependent proteins.
PubMed:	The occurrence of beta-hydroxyaspartic acid in the vitamin K-dependent blood coagulation zymogens.
PubMed:	Complete amino acid sequence of the light chain of human blood coagulation factor X: evidence for identification of residue 63 as beta-hydroxyaspartic acid.
PubMed:	Effects of anoxia on the stimulated release of amino acid neurotransmitters in the cerebellum in vitro.
PubMed:	Potentiation of L-glutamate and L-aspartate excitation of cat spinal neurones by the stereoisomers of threo-3-hydroxyaspartate.