cycloeucalenol
4a,14-dimethyl-9b,19-cyclo-5a-ergost-24(28)-en-3b-ol
 
Notes:
None found
  • BOC Sciences
    • BOC Sciences
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      Product(s):
      469-39-6 Cycloeucalenol >95%
      Cycloeucalenol is founf from the stems of Tinospora crispa, it produces mild cardiotonic effects.
       
       
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CAS Number: 469-39-6Picture of molecule3D/inchi
FDA UNII: 7OF1Q9UE9R
XlogP3-AA: 9.90 (est)
Molecular Weight: 426.72770000
Formula: C30 H50 O
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 508.00 °C. @ 760.00 mm Hg (est)
Flash Point: 433.00 °F. TCC ( 222.70 °C. ) (est)
logP (o/w): 10.540 (est)
Soluble in:
 water, 2.124e-005 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
BOC Sciences
For experimental / research use only.
Cycloeucalenol >95%
Odor: characteristic
Use: Cycloeucalenol is founf from the stems of Tinospora crispa, it produces mild cardiotonic effects.
Coompo
For experimental / research use only.
Cycloleucalenol from Plants ≥96%
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for cycloeucalenol usage levels up to:
 not for fragrance use.
 
Recommendation for cycloeucalenol flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 101690
National Institute of Allergy and Infectious Diseases: Data
Chemidplus: 0000469396
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References:
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 101690
Pubchem (sid): 135058829
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
Golm Metabolome Database: Search
KEGG (GenomeNet): C02141
HMDB (The Human Metabolome Database): Search
FooDB: FDB014882
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
Wikipedia2: View2
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 banana fruit
Search Trop  Picture
 coffee bean
Search Trop  Picture
 corn shoot
Search Trop  Picture
 cucumber seed
Search Trop  Picture
 onion bulb
Search Trop  Picture
 pepper bell pepper seed
Search Trop  Picture
 rice seed
Search Trop  Picture
 sesame seed oil
Search Trop  Picture
 tomato seed
Search Trop  Picture
 watermelon seed
Search Trop  Picture
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Synonyms:
9,19-cycloergost-24(28)-en-3-ol, 4,14-dimethyl-, (3b,4a,5a,9b)-
 cycloleucalenol
(3b,4a,5a,9b)-4,14-dimethyl-9,19-cycloergost-24(28)-en-3-ol
(3beta,4alpha,5alpha)-4,14-dimethyl-9,19-cycloergost-24(28)-en-3-ol
3b,4a,5a-4,14-dimethyl-9,19-cycloergost-24(28)-en-3-ol
4a,14-dimethyl-9b,19-cyclo-5a-ergost-24(28)-en-3b-ol
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Articles:
PubMed: Antioxidant properties of isolated compounds from banana rhizome.
PubMed: A review on phytochemical, pharmacological, and pharmacognostical profile of Wrightia tinctoria: Adulterant of kurchi.
PubMed: Plant cyclopropylsterol-cycloisomerase: key amino acids affecting activity and substrate specificity.
PubMed: Isolation of cycloeucalenol from Boophone disticha and evaluation of its cytotoxicity.
PubMed: [Study on the chemical constituents of Chloranthus multistachys].
PubMed: Investigation of unsaponifiable matter of plant oils and isolation of eight phytosterols by means of high-speed counter-current chromatography.
PubMed: Two new triterpenoids from the leaves and stems of Fritillaria hupehensis.
PubMed: [A novel azo-type compound from Dendrolobium triangulare].
PubMed: [Chemical constituents from fruits of Ailanthus altissima].
PubMed: 5 alpha-reductase and aromatase inhibitory constituents from Brassica rapa L. pollen.
PubMed: Two new components from Gnetum pendulum.
PubMed: Sterol-dependent endocytosis mediates post-cytokinetic acquisition of PIN2 auxin efflux carrier polarity.
PubMed: Biological activities of the chemical constituents of Erythrina stricta and Erythrina subumbrans.
PubMed: [Chemical constituents from root barks of Periploca sepium].
PubMed: Diterpenoids and triterpenoids from Euphorbia guyoniana.
PubMed: Insights into the role of specific lipids in the formation and delivery of lipid microdomains to the plasma membrane of plant cells.
PubMed: [Chemical constituents from herb of Alternanthera philoxeroides].
PubMed: Biotransformation of cycloartane-type triterpenes by the fungus Glomerella fusarioides.
PubMed: Mechanism involved in the spasmolytic effect of a mixture of two triterpenes, cycloartenol and cycloeucalenol, isolated from Herissanthia tiubae in the guinea-pig ileum.
PubMed: Study on cardiac contractility of cycloeucalenol and cycloeucalenone isolated from Tinospora crispa.
PubMed: Inhibition of the sterol pathway in leek seedlings impairs phosphatidylserine and glucosylceramide synthesis but triggers an accumulation of triacylglycerols.
PubMed: Cycloartane triterpenes from Euphorbia tuckeyana.
PubMed: Triterpene alcohol and sterol ferulates from rice bran and their anti-inflammatory effects.
PubMed: Alkaloids and triterpenoids from Ammocharis coranica (Amaryllidaceae).
PubMed: Functional cloning of an Arabidopsis thaliana cDNA encoding cycloeucalenol cycloisomerase.
PubMed: Sterol biosynthesis: strong inhibition of maize delta 5,7-sterol delta 7-reductase by novel 6-aza-B-homosteroids and other analogs of a presumptive carbocationic intermediate of the reduction reaction.
PubMed: Plant sterol biosynthesis. Identification and characterization of two distinct microsomal oxidative enzymatic systems involved in sterol C4-demethylation.
PubMed: Oxidative C4-demethylation of 24-methylene cycloartanol by a cyanide-sensitive enzymatic system from higher plant microsomes.
PubMed: Analysis of a thread used in the Kshara Sutra treatment in the Ayurvedic medicinal system.
PubMed: Microsomal delta 8,14-sterol delta 14-reductase in higher plants. Characterization and inhibition by analogues of a presumptive carbocationic intermediate of the reduction reaction.
PubMed: Cyclopropyl sterol and phospholipid composition of membrane fractions from maize roots treated with fenpropimorph.
PubMed: Cycloeucalenol-obtusifoliol isomerase. Structural requirements for transformation or binding of substrates and inhibitors.
PubMed: Paclobutrazol inhibition of sterol biosynthesis in a cell suspension culture and evidence of an essential role for 24-ethylsterol in plant cell division.
PubMed: Inhibition of 2,3-oxidosqualene: beta-amyrin-cyclase, S-adenosyl-L-methionine: cycloartenol C-24-methyltransferase and cycloeucalenol: obtusifoliol isomerase by rationally designed molecules containing a tertiary amine function.
PubMed: Manipulation by tridemorph, a systemic fungicide, of the sterol composition of maize leaves and roots.
PubMed: [Triterpenes and steroids in seeds of Solanum dulcamara].
PubMed: Analysis of methylsterol fractions from twenty vegetable oils.
PubMed: Plant sterol metabolism. Studies on the substrate specificity of an enzyme capable of opening the cyclopropane ring of cycloeucalenol.
PubMed: Evidence for the presence of an enzyme capable of opening the cyclopropane ring of cycloeucalenol.
PubMed: Studies on phytosterol biosynthesis. The presence of 4-alpha,14-alpha-dimethyl-delta-8,24(28)-ergostadien-3-beta-ol in grapefruit peel and its co-occurrece with cycloeucalenol in higher plant tissues.
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