|
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
|
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 478.30 °C. @ 760.00 mm Hg (est)
|
| Flash Point: | 391.00 °F. TCC ( 199.60 °C. ) (est)
|
| logP (o/w): | 11.450 (est) |
| Soluble in: |
| | water, 7.845e-005 mg/L @ 25 °C (est) |
Organoleptic Properties:
| |
| Odor and/or flavor descriptions from others (if found). |
| |
| |
Cosmetic Information:
Suppliers:
| Alfa Biotechnology |
| For experimental / research use only. |
| Epifriedelanol 98%
|
| BOC Sciences |
| For experimental / research use only. |
| epifriedelanol 99%
Odor: characteristic Use: Epifriedelanol isolated from the herbs of Vitis trifolia. It suppresses adriamycin-induced cellular senescence, replicative senescence in human fibroblasts and human umbilical vein endothelial cells. |
| Coompo |
| For experimental / research use only. |
| EpiFriedelanol from Plants ≥96%
Odor: characteristic Use: Epifriedelanol had inhibitory effects on adriamycin-induced cellular senescence in human fibroblasts (HDFs). Epifriedelanol suppressed adriamycin-induced cellular senescence as well as replicative senescence in human fibroblasts (HDFs) and human umbilical vein endothelial cells (HUVECs). These results suggest that epifriedelanol reduces cellular senescence in human primary cells and might be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases.
Epifriedelanol demonstrated antitumor activity in a potato disc bioassay. |
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for epifriedelanol usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for epifriedelanol flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 119242 |
| National Institute of Allergy and Infectious Diseases: | Data |
| | (3S,4R,4aS,6aS,6aS,6bR,8aR,12aR,14aS,14bS)-4,4a,6a,6b,8a,11,11,14a-octamethyl-1,2,3,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-hexadecahydropicen-3-ol |
| Chemidplus: | 0016844716 |
References:
| | (3S,4R,4aS,6aS,6aS,6bR,8aR,12aR,14aS,14bS)-4,4a,6a,6b,8a,11,11,14a-octamethyl-1,2,3,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-hexadecahydropicen-3-ol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 119242 |
| Pubchem (sid): | 135074735 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| epi- | friedelanol | | epi | friedelinol | | (3S,4R,4aS,6aS,6aS,6bR,8aR,12aR,14aS,14bS)-4,4a,6a,6b,8a,11,11,14a- | octamethyl-1,2,3,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-hexadecahydropicen-3-ol | | (3S,4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-4,4a,6b,8a,11,11,12b,14a- | octamethyldocosahydro-3-picenol | | (3S,4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)-4,4a,6b,8a,11,11,12b,14a- | octamethyldocosahydropicen-3-ol | | 3- | picenol, docosahydro-4,4a,6b,8a,11,11,12b,14a-octamethyl-, (3S,4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS)- | | (3beta,4beta,5beta,8alpha,9beta,10alpha,13alha,14beta)-5,9,13- | trimethyl-24,25,26-trinoroleanan-3-ol |
Articles:
|