isosilybin, 72581-71-6

Articles:

PubMed:	Chemoenzymatic Synthesis, Characterization, and Scale-up of Milk Thistle Flavonolignan Glucuronides.
PubMed:	Synchronous microencapsulation of multiple components in silymarin into PLGA nanoparticles by an emulsification/solvent evaporation method.
PubMed:	Pyranone natural products as inspirations for catalytic reaction discovery and development.
PubMed:	Accumulation of silymarin in milk thistle seeds under drought stress.
PubMed:	A biomimetic strategy to access the silybins: total synthesis of (-)-isosilybin A.
PubMed:	The effects of milk thistle (Silybum marianum) on human cytochrome P450 activity.
PubMed:	Isolation and purification of diastereoisomeric flavonolignans from silymarin by binary-column recycling preparative high-performance liquid chromatography.
PubMed:	Simplified procedure of silymarin extraction from Silybum marianum L. Gaertner.
PubMed:	Identification of isosilybin a from milk thistle seeds as an agonist of peroxisome proliferator-activated receptor gamma.
PubMed:	Flavonolignans from Aspergillus iizukae, a fungal endophyte of milk thistle (Silybum marianum).
PubMed:	Biotransformation on the flavonolignan constituents of Silybi Fructus by an intestinal bacterial strain Eubacterium limosum ZL-II.
PubMed:	Mechanistic study of the biomimetic synthesis of flavonolignan diastereoisomers in milk thistle.
PubMed:	An assessment of pharmacokinetics and antioxidant activity of free silymarin flavonolignans in healthy volunteers: a dose escalation study.
PubMed:	A systematic approach to evaluate herb-drug interaction mechanisms: investigation of milk thistle extracts and eight isolated constituents as CYP3A inhibitors.
PubMed:	Milk thistle's active components silybin and isosilybin: novel inhibitors of PXR-mediated CYP3A4 induction.
PubMed:	HiFSA fingerprinting applied to isomers with near-identical NMR spectra: the silybin/isosilybin case.
PubMed:	Synchronized and controlled release of multiple components in silymarin achieved by the osmotic release strategy.
PubMed:	Absolute configuration of isosilybin A by X-ray crystallography of the heavy atom analogue 7-(4-Bromobenzoyl)isosilybin A.
PubMed:	Absorption and metabolism of milk thistle flavanolignans in humans.
PubMed:	A sensitive LC-MS/MS assay for the simultaneous analysis of the major active components of silymarin in human plasma.
PubMed:	Angiopreventive efficacy of pure flavonolignans from milk thistle extract against prostate cancer: targeting VEGF-VEGFR signaling.
PubMed:	Pyrazinecarboxamides as potential elicitors of flavonolignan and flavonoid production in Silybum marianum and Ononis arvensis cultures in vitro.
PubMed:	Electrochemical investigation of flavonolignans and study of their interactions with DNA in the presence of Cu(II).
PubMed:	Effects of silymarin nanoemulsion against carbon tetrachloride-induced hepatic damage.
PubMed:	Isosilybin A induces apoptosis in human prostate cancer cells via targeting Akt, NF-κB, and androgen receptor signaling.
PubMed:	Enhanced production of silymarin by Ag+ elicitor in cell suspension cultures of Silybum marianum.
PubMed:	Identification of hepatoprotective flavonolignans from silymarin.
PubMed:	Large-scale isolation of flavonolignans from Silybum marianum extract affords new minor constituents and preliminary structure-activity relationships.
PubMed:	Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.
PubMed:	Influence of exogenous salicylic acid on flavonolignans and lipoxygenase activity in the hairy root cultures of Silybum marianum.
PubMed:	[Silymarin in the treatment of chronic liver diseases: past and future].
PubMed:	Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin.
PubMed:	Hepatic metabolism and biliary excretion of silymarin flavonolignans in isolated perfused rat livers: role of multidrug resistance-associated protein 2 (Abcc2).
PubMed:	Identifying the differential effects of silymarin constituents on cell growth and cell cycle regulatory molecules in human prostate cancer cells.
PubMed:	New insight into the biosynthesis of flavanolignans in the white-flowered variant of Silybum marianum.
PubMed:	Isosilybin B causes androgen receptor degradation in human prostate carcinoma cells via PI3K-Akt-Mdm2-mediated pathway.
PubMed:	Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (Milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention.
PubMed:	Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract.
PubMed:	Inhibition of T-cell inflammatory cytokines, hepatocyte NF-kappaB signaling, and HCV infection by standardized Silymarin.
PubMed:	Isosilybin B and isosilybin A inhibit growth, induce G1 arrest and cause apoptosis in human prostate cancer LNCaP and 22Rv1 cells.
PubMed:	Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine.
PubMed:	Anticancer potential of silymarin: from bench to bed side.
PubMed:	Synchronized and sustained release of multiple components in silymarin from erodible glyceryl monostearate matrix system.
PubMed:	Structure elucidation and antioxidant activity of (-)-isosilandrin isolated from Silybum marianum L.
PubMed:	Analysis and comparison of active constituents in commercial standardized silymarin extracts by liquid chromatography-electrospray ionization mass spectrometry.
PubMed:	Separation and characterization of silybin, isosilybin, silydianin and silychristin in milk thistle extract by liquid chromatography-electrospray tandem mass spectrometry.
PubMed:	Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin.
PubMed:	Milk thistle and prostate cancer: differential effects of pure flavonolignans from Silybum marianum on antiproliferative end points in human prostate carcinoma cells.
PubMed:	Molecular structure and stereochemistry of silybin A, silybin B, isosilybin A, and isosilybin B, Isolated from Silybum marianum (milk thistle).
PubMed:	Analysis of the active components of silymarin.
PubMed:	Primary cultures of human hepatocytes as a tool in cytotoxicity studies: cell protection against model toxins by flavonolignans obtained from Silybum marianum.
PubMed:	[Determination of the active flavonoids in silymarine].
PubMed:	Inhibition of the superoxide anion release and hydrogen peroxide formation in PMNLs by flavonolignans.
PubMed:	Determination of active component in silymarin by RP-LC and LC/MS.
PubMed:	[Separation and determination of effective components in silymarin and preparations of silymarin by MECC].
PubMed:	Flavonolignan production from Silybum marianum transformed and untransformed root cultures.
PubMed:	Comparative pharmacokinetics of silipide and silymarin in rats.
PubMed:	Pharmacokinetics of silybin in bile following administration of silipide and silymarin in cholecystectomy patients.
PubMed:	Effect of the flavanolignans of Silybum marianum L. on lipid peroxidation in rat liver microsomes and freshly isolated hepatocytes.
PubMed:	[Structure of silandrin and silymonin, two new flavanolignans from a white blooming Silybum marianum variety].