cetyl palmitate
palmityl palmitate
 
Notes:
None found
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CAS Number: 100231-74-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 309-375-8
FDA UNII: 5ZA2S6B08X
Nikkaji Web: J65.556B
XlogP3-AA: 15.20 (est)
Molecular Weight: 480.86048000
Formula: C32 H64 O2
NMR Predictor: Predict (works with chrome or firefox)
Category: natural substances and extractives
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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PubMed: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 507.00 °C. @ 760.00 mm Hg (est)
Flash Point: 518.00 °F. TCC ( 269.80 °C. ) (est)
logP (o/w): 15.590 (est)
Soluble in:
 water, 3.134e-010 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: natural substances and extractives
Recommendation for cetyl palmitate usage levels up to:
 not for fragrance use.
 
Recommendation for cetyl palmitate flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 10889
National Institute of Allergy and Infectious Diseases: Data
WGK Germany: nwg
 hexadecyl hexadecanoate
Chemidplus: 0100231741
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References:
 hexadecyl hexadecanoate
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 10889
Pubchem (sid): 134978807
Pherobase: View
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C13821
HMDB (The Human Metabolome Database): Search
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
 hexadecyl hexadecanoate
 hexadecyl palmitate
 palmityl palmitate
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Articles:
PubMed: Formulation of solid lipid nanoparticles (SLN): The value of different alkyl polyglucoside surfactants.
PubMed: Idebenone loaded solid lipid nanoparticles: calorimetric studies on surfactant and drug loading effects.
PubMed: FA-loaded lipid drug delivery systems: preparation, characterization and biological studies.
PubMed: Influence of process parameters on properties of Nanostructured Lipid Carriers (NLC) formulation.
PubMed: Improved brain delivery of vincristine using dextran sulfate complex solid lipid nanoparticles: optimization and in vivo evaluation.
PubMed: Modeling the effect of sonication parameters on size and dispersion temperature of solid lipid nanoparticles (SLNs) by response surface methodology (RSM).
PubMed: All-trans retinoic acid-loaded lipid nanoparticles as a transdermal drug delivery carrier.
PubMed: Lipid nanoparticles based on butyl-methoxydibenzoylmethane: in vitro UVA blocking effect.
PubMed: Idebenone-loaded solid lipid nanoparticles for drug delivery to the skin: in vitro evaluation.
PubMed: In vitro evaluation on a model of blood brain barrier of idebenone-loaded solid lipid nanoparticles.
PubMed: Solid lipid nanoparticles as intracellular drug transporters: an investigation of the uptake mechanism and pathway.
PubMed: Combined strategies of apomorphine diester prodrugs and nanostructured lipid carriers for efficient brain targeting.
PubMed: Multivariate design for the evaluation of lipid and surfactant composition effect for optimisation of lipid nanoparticles.
PubMed: Preparation and optimization of PIT solid lipid nanoparticles via statistical factorial design.
PubMed: Fabrication, appraisal, and transdermal permeation of sildenafil citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles.
PubMed: Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size.
PubMed: Nanostructured lipid carriers (NLC) for parenteral delivery of an anticancer drug.
PubMed: Development and validation of a simple reversed-phase HPLC method for the determination of camptothecin in animal organs following administration in solid lipid nanoparticles.
PubMed: In vivo real-time fluorescence visualization and brain-targeting mechanisms of lipid nanocarriers with different fatty ester:oil ratios.
PubMed: Dissolution of solid lipid extrudates in biorelevant media.
PubMed: Hydrophilic coating of mitotane-loaded lipid nanoparticles: preliminary studies for mucosal adhesion.
PubMed: Lipid nanoparticles for brain targeting I. Formulation optimization.
PubMed: Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies.
PubMed: Cysteine proteinase type I, encapsulated in solid lipid nanoparticles induces substantial protection against Leishmania major infection in C57BL/6 mice.
PubMed: Polyhydroxy surfactants for the formulation of lipid nanoparticles (SLN and NLC): effects on size, physical stability and particle matrix structure.
PubMed: In vitro evaluation of idebenone-loaded solid lipid nanoparticles for drug delivery to the brain.
PubMed: Cationic solid lipid nanoparticles loaded by cysteine proteinase genes as a novel anti-leishmaniasis DNA vaccine delivery system: characterization and in vitro evaluations.
PubMed: Physicochemical characterization and in vivo bioluminescence imaging of nanostructured lipid carriers for targeting the brain: apomorphine as a model drug.
PubMed: The influence of lipid characteristics on the formation, in vitro release, and in vivo absorption of protein-loaded SLN prepared by the double emulsion process.
PubMed: Preparation, optimization and characteristic of huperzine a loaded nanostructured lipid carriers.
PubMed: Nondestructive rheological measurement of aqueous dispersions of solid lipid nanoparticles: effects of lipid types and concentrations on dispersion consistency.
PubMed: Chemical and structural investigation of lipid nanoparticles: drug-lipid interaction and molecular distribution.
PubMed: Corticosteroid solubility and lipid polarity control release from solid lipid nanoparticles.
PubMed: Lipid nanoparticles with different oil/fatty ester ratios as carriers of buprenorphine and its prodrugs for injection.
PubMed: Influence of oil content on physicochemical properties and skin distribution of Nile red-loaded NLC.
PubMed: In vitro skin permeation of sunscreen agents from O/W emulsions.
PubMed: The effect of cetyl palmitate crystallinity on physical properties of gamma-oryzanol encapsulated in solid lipid nanoparticles.
PubMed: Oral insulin delivery by means of solid lipid nanoparticles.
PubMed: Cetyl palmitate-based NLC for topical delivery of Coenzyme Q(10) - development, physicochemical characterization and in vitro release studies.
PubMed: Development and evaluation of nitrendipine loaded solid lipid nanoparticles: influence of wax and glyceride lipids on plasma pharmacokinetics.
PubMed: A water activity control system for enzymatic reactions in organic media.
PubMed: Solid lipid nanoparticles (SLN)--effects of lipid composition on in vitro degradation and in vivo toxicity.
PubMed: Preparation and characterization of n-dodecyl-ferulate-loaded solid lipid nanoparticles (SLN).
PubMed: Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique.
PubMed: The development of Cutina lipogels and gel microemulsion for topical administration of fluconazole.
PubMed: Semisolid SLN dispersions for topical application: influence of formulation and production parameters on viscoelastic properties.
PubMed: Solid lipid nanoparticles (SLN)--a novel carrier for UV blockers.
PubMed: Bioavailability of diazepam from aqueous-organic solution, submicron emulsion and solid lipid nanoparticles after rectal administration in rabbits.
PubMed: Encapsulation of retinoids in solid lipid nanoparticles (SLN).
PubMed: Preserved solid lipid nanoparticles (SLN) at low concentrations do cause neither direct nor indirect cytotoxic effects in peritoneal macrophages.
PubMed: Comparison of wax and glyceride solid lipid nanoparticles (SLN).
PubMed: Crystallographic investigation of cetylpalmitate solid lipid nanoparticles.
PubMed: Solid lipid nanoparticles (SLN/Lipopearls)--a pharmaceutical and cosmetic carrier for the application of vitamin E in dermal products.
PubMed: Spray-drying of solid lipid nanoparticles (SLN TM).
PubMed: Effect of topical preparation of mycophenolic acid on experimental allergic contact dermatitis of guinea-pigs induced by dinitrofluorobenzene.
PubMed: The esterase profile of a lipase from Candida cylindracea.
PubMed: Growth of Acinetobacter sp. strain HO1-N on n-hexadecanol: physiological and ultrastructural characteristics.
PubMed: Collaborative study of a GLC method for vitamin E.
PubMed: [Aqueous petroleum-oxidizing Arthrobacter].
PubMed: [Formation of cetyl palmitate from n-hexadecane by Mycobacterium strain 3' cultures].
PubMed: ORIGIN OF PALMITIC ACID CARBON IN PALMITATES FORMED FROM HEXADECANE-1-C-14 AND TETRADECANE-1-C-14 BY MICROCOCCUS CERIFICANS.
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