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Category: pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 223.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 576.56 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 385.00 °F. TCC ( 196.20 °C. ) (est)
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| logP (o/w): | 2.190 |
| Soluble in: |
| | water, 38.71 mg/L @ 25 °C (est) | | | water, 14.1 mg/L @ 25 °C (exp) |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 2300 mg/kg Compilation of LD50 Values of New Drugs.
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| Dermal Toxicity: |
subcutaneous-mouse LD50 45050 ug/kg National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986
subcutaneous-rat LDLo 250 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 27, Pg. 2102, 1977.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | pharmaceuticals / chemical synthisis |
| Recommendation for hydrocortisone acetate usage levels up to: | | | not for fragrance use.
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| Recommendation for hydrocortisone acetate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: | View |
| ClinicalTrials.gov: | search |
| Daily Med: | search |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 5744 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| | [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate |
| Chemidplus: | 0000050033 |
| RTECS: | GM8960000 for cas# 50-03-3 |
References:
| | [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate |
| NIST Chemistry WebBook: | Search Inchi |
| Canada Domestic Sub. List: | 50-03-3 |
| Pubchem (cid): | 5744 |
| Pubchem (sid): | 134970850 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | ab bocort | | | abbocort | | | acepolcort-H | | | acetate-AS | | | aceto-cort | | 21-( | acetyl oxy)-11,17-pregn-4-ene-3,20-dione | | 21-O- | acetylcortisol | | | alfacorton | | | allocort | | | bacicoline | | | bambicort | | | berlison | | | biocortar | | | caldecort | | | carmol HC | | | carmol-HC | | | chemysone | | | chloromycetin hydrocortisone ophthalmic | | | clear-aid | | | colifoam | | | collusul-HC | | | colofoam | | | cortacream | | | cortaid | | | cortef acetate | | | cortell | | | cortes | | | corti | | | crema transcutan | | | crematranscutan | | | derminovag | | | dermosa hidrocortisona | | [2-[(8S,9S,10R,11S,13S,14S,17R)-11,17- | dihydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate | | | dricort | | | efcolin | | | efcorlin | | | efzem | | | ekzemsalbe F | | | epifoam | | | fenitral | | | fernisone | | | glycocortison | | | hemsol-HC | | | hipokort | | | hycor eye oitment | | | hycortole acetate | | | hyderm | | | hydrin-2 | | | hydrison | | | hydrocal | | 17a- | hydrocorticosterone-21-acetate | | | hydrocortisat | | | hydrocortison | | | hydrocortisone 21-acetate | | | hydrocortistab | | | hydrocortole acetate | | | hydrocortone acetate | | | hydrosone | | 17- | hydroxycorticosterone 21-acetate | | 17-a- | hydroxycorticosterone 21-acetate | | | hydroxycorticosterone acetate | | 17-a- | hydroxycorticosterone acetate | | 17- | hydroxycorticosterone, 21-acetate | | | hysone-A | | | idrocort | | | iracetisone | | | korti | | | lanacort | | | latimit | | | lenirit | | | lidaform-HC | | | lidamantle-HC | | | mantadil | | | medithane | | | micort-HC | | | ophticor | | | orabase HCA | | | pabracort | | | pannocort | | | pregn-4-ene-3, 20-dione, 11b,17,21-trihydroxy-, 21-acetate | | | pregn-4-ene-3, 20-dione, 21- (acetyloxy)-11,17-dihydroxy-, (11b)- | | | pregn-4-ene-3,20-dione, 11-b,17,21-trihydroxy-, 21-acetate | | | pregn-4-ene-3,20-dione, 11b,17,21-trihydroxy-, 21-acetate | | | pregn-4-ene-3,20-dione, 21-(acetoxy)-11,17-dihydroxy-, (11-b)- | | iso | pto-hydrocortisone | | | resicort | | | sagittacortin | | | sanadermil | | | sigma cort | | | sigmacort | | | siguent hycor | | | sintotrat | | | soenol hydrocortison | | | squibb-HC | | | supralef | | | urecortyn | | | velopural | | | wycort |
Articles:
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