1'-hydroxysafrole, 5208-87-7

Articles:

PubMed:	Roles of human sulfotransferases in genotoxicity of carcinogens using genetically engineered umu test strains.
PubMed:	Physiologically based biokinetic (PBBK) model for safrole bioactivation and detoxification in rats.
PubMed:	Sulfotransferase 1A1 haplotypes associated with oral squamous cell carcinoma susceptibility in male Taiwanese.
PubMed:	SULT1C3, an orphan sequence of the human genome, encodes an enzyme activating various promutagens.
PubMed:	Human cytochrome p450 enzyme specificity for bioactivation of safrole to the proximate carcinogen 1'-hydroxysafrole.
PubMed:	Identification of the main human cytochrome P450 enzymes involved in safrole 1'-hydroxylation.
PubMed:	Safrole-like DNA adducts in oral tissue from oral cancer patients with a betel quid chewing history.
PubMed:	Sulfotransferase-mediated activation of mutagens studied using heterologous expression systems.
PubMed:	Sulfation and sulfotransferases 4: bioactivation of mutagens via sulfation.
PubMed:	Human dehydroepiandrosterone sulfotransferase. Purification, molecular cloning, and characterization.
PubMed:	Salmonella strains and mammalian cells genetically engineered for expression of sulfotransferases.
PubMed:	Enhancement of computed tomography liver contrast using iomeprol-containing liposomes and detection of small liver tumors in rats.
PubMed:	Structure-activity studies of the hepatocarcinogenicities of alkenylbenzene derivatives related to estragole and safrole on administration to preweanling male C57BL/6J x C3H/HeJ F1 mice.
PubMed:	Inhibition by pentachlorophenol of the initiating and promoting activities of 1'-hydroxysafrole for the formation of enzyme-altered foci and tumors in rat liver.
PubMed:	The metabolic sulfonation and side-chain oxidation of 3'-hydroxyisosafrole in the mouse and its inactivity as a hepatocarcinogen relative to 1'-hydroxysafrole.
PubMed:	Differences in the covalent binding of benzo[a]pyrene, safrole, 1'-hydroxysafrole, and 4-aminobiphenyl to DNA of pregnant and non-pregnant mice.
PubMed:	Electrophilic sulfuric acid ester metabolites as ultimate carcinogens.
PubMed:	Further characterization of the DNA adducts formed by electrophilic esters of the hepatocarcinogens 1'-hydroxysafrole and 1'-hydroxyestragole in vitro and in mouse liver in vivo, including new adducts at C-8 and N-7 of guanine residues.
PubMed:	Ligand-complex formation between cytochromes P-450 and P-448 and methylenedioxyphenyl compounds.
PubMed:	Sulfuric acid esters as ultimate electrophilic and carcinogenic metabolites of some alkenylbenzenes and aromatic amines in mouse liver.
PubMed:	Characterization of the biliary and urinary glutathione and N-acetylcysteine metabolites of the hepatic carcinogen 1'-hydroxysafrole and its 1'-oxo metabolite in rats and mice.
PubMed:	Strong evidence from studies with brachymorphic mice and pentachlorophenol that 1'-sulfoöxysafrole is the major ultimate electrophilic and carcinogenic metabolite of 1'-hydroxysafrole in mouse liver.
PubMed:	Structure-activity studies of the carcinogenicities in the mouse and rat of some naturally occurring and synthetic alkenylbenzene derivatives related to safrole and estragole.
PubMed:	N2 atom of guanine and N6 atom of adenine residues as sites for covalent binding of metabolically activated 1'-hydroxysafrole to mouse liver DNA in vivo.
PubMed:	The in vivo formation and repair of DNA adducts from 1'-hydroxysafrole.
PubMed:	The mutagenicities of safrole, estragole, eugenol, trans-anethole, and some of their known or possible metabolites for Salmonella typhimurium mutants.
PubMed:	In vitro assays for recombinogenic activity of chemical carcinogens and related compounds with Saccharomyces cerevisiae D3.
PubMed:	Metabolism of the proximate carcinogen 1'-hydroxysafrole and the isomer 3'-hydroxyisosafrole.
PubMed:	Carcinogenic and mutagenic activities of safrole, 1'-hydroxysafrole, and some known or possible metabolites.
PubMed:	Absorption, metabolism and excretion of safrole in the rat and man.
PubMed:	[Mutagenicity of the metabolites of the epoxide-diol pathway of safrole and its analogs. Study on Salmonella typhimurium].
PubMed:	Hepatocarcinogenicity of estragole (1-allyl-4-methoxybenzene) and 1'-hydroxyestragole in the mouse and mutagenicity of 1'-acetoxyestragole in bacteria.
PubMed:	The metabolic activation of the carcinogen 1'-hydroxysafrole in vivo and in vitro and the electrophilic reactivities of possible ultimate carcinogens.
PubMed:	The metabolism of the naturally occurring hepatocarcinogen safrole to 1'-hydroxysafrole and the electrophilic reactivity of 1'-acetoxysafrole.
PubMed:	1'-Hydroxysafrole, a proximate carcinogenic metabolite of safrole in the rat and mouse.