Articles:
| PubMed: | Pogostemon hirsutus oil, rich in abietane diterpenes. |
| PubMed: | An interpopulation study of the essential oils of Cistus parviflorus L. growing in Crete (Greece). |
dehydroabietadienol
Notes:
None found
| CAS Number: | 3772-55-2 |  3D/inchi
|
| Other: | 19426-88-1 | |
| ECHA EINECS - REACH Pre-Reg: | 223-217-4 | |
| FDA UNII: | VAD5Q9VDSM | |
| Nikkaji Web: | J146.752B | |
| XlogP3-AA: | 5.70 (est) | |
| Molecular Weight: | 286.45830000 | |
| Formula: | C20 H30 O | |
| BioActivity Summary: | listing | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 389.40 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 277.00 °F. TCC ( 136.20 °C. ) (est) |
| logP (o/w): | 6.350 (est) |
| Soluble in: | |
| water, 0.2007 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Coompo |
| For experimental / research use only. |
| Dehydroabietinol from Plants ≥96%
Odor: characteristic Use: Dehydroabietinol was found to inhibit growth of chloroquine-sensitive as well as chloroquine-resistant strains of Plasmodium falciparum cultivated in erythrocytes in vitro (IC 50 26-27 microM). However, erythrocytes exposed to dehydroabietinol were transformed in a dose-dependent manner towards spherostomatocytic forms with concomitant formation of endovesicles, as disclosed by transmission electron microscopy. The erythrocyte shape alterations caused by dehydroabietinol correlated well with its apparent IC50 value. Thus, dehydroabietinol incorporates into the erythrocyte membrane, and since invasion and survival of Plasmodium parasites is known to depend on the function of the erythrocyte membrane, the observed antiplasmodial effect of dehydroabietinol is presumably an indirect effect on the host cell. Because of these findings, microscopic investigations should be generally used to support claims of antimalarial effects of apolar natural products. |
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Dehydroabietol |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | natural substances and extractives | ||
| Recommendation for dehydroabietol usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for dehydroabietol flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 3772-55-2 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 15586718 |
| National Institute of Allergy and Infectious Diseases: | Data |
| [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanol | |
| Chemidplus: | 0003772552 |
References:
| [(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanol | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 15586718 |
| Pubchem (sid): | 135063931 |
| Pherobase: | View |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| CHEMBL: | View |
| HMDB (The Human Metabolome Database): | Search |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| found in nature |
Synonyms:
| abieta-8,11,13-trien-18-ol | |
| dehydroabeityl alcohol | |
| dehydroabietadienol | |
| dehydroabietinol | |
| [(1R,4aS,10aR)-1,4a- | dimethyl-7-propan-2-yl-2,3,4,9,10,10a-hexahydrophenanthren-1-yl]methanol |
| (1R-(1alpha,4abeta,10aalpha))-1,2,3,4,4a,9,10,10a- | octahydro-7-isopropyl-1,4a-dimethyl phenanthren-1-methanol |
| 1- | phenanthrenemethanol, 1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-, (1R,4aS,10aR)- |
| podocarpa-8,11,13-trien-15-ol, 13-isopropyl- | |
| pomiferin A | |
| [(1R,4aS,10aR)-7-iso | propyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl]methanol |