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Category: natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00 %
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 231.00 to 232.00 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.012000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 196.00 °F. TCC ( 91.20 °C. ) (est)
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| logP (o/w): | 2.819 (est) |
| Soluble in: |
| | alcohol | | | water, 519.7 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
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| Odor and/or flavor descriptions from others (if found). |
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Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | natural substances and extractives |
| Recommendation for (4R,6S)-carveol usage levels up to: | | | not for fragrance use.
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| Recommendation for (4R,6S)-carveol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (-)-(4R,6S)-trans- | carveol | | (-)-(E)- | carveol | | (-)-trans- | carveol | | (4R,6S)-trans- | carveol | | 2- | cyclohexen-1-ol, 2-methyl-5-(1-methylethenyl)-, (1S,5R)- | | (4R,6S)-p- | mentha-1,8-dien-6-ol | | (1S,5R)-2- | methyl-5-(1-methyl ethenyl)-2-cyclohexen-1-ol | | (1S-trans)-2- | methyl-5-(1-methyl vinyl) cyclohex-2-en-1-ol | | (1S-trans)-2- | methyl-5-(1-methylethenyl)-2-cyclohexen-1-ol | | (1S,5R)-2- | methyl-5-(1-methylethenyl)-2-cyclohexen-1-ol | | (1S-trans)-2- | methyl-5-(1-methylvinyl)cyclohex-2-en-1-ol | | (1S,5R)-2- | methyl-5-(prop-1-en-2-yl)cyclohex-2-en-1-ol | | (1S,5R)-2- | methyl-5-prop-1-en-2-ylcyclohex-2-en-1-ol |
Articles:
| PubMed: | Chemical composition, cytotoxicity and in vitro antitrypanosomal and antiplasmodial activity of the essential oils of four Cymbopogon species from Benin. |
| PubMed: | Chemical composition and biological activities of Tunisian Cuminum cyminum L. essential oil: a high effectiveness against Vibrio spp. strains. |
| PubMed: | Improved reactor performance and operability in the biotransformation of carveol to carvone using a solid-liquid two-phase partitioning bioreactor. |
| PubMed: | Phosphotungstic acid as a versatile catalyst for the synthesis of fragrance compounds by alpha-pinene oxide isomerization: solvent-induced chemoselectivity. |
| PubMed: | Enhanced bioproduction of carvone in a two-liquid-phase partitioning bioreactor with a highly hydrophobic biocatalyst. |
| PubMed: | Inhibitory effects of substrate and product on the carvone biotransformation activity of Rhodococcus erythropolis. |
| PubMed: | Chemical composition and antimicrobial activity of the essential oil from Ambrosia trifida L. |
| PubMed: | Regio- and stereoselective fungal oxyfunctionalisation of limonenes. |
| PubMed: | Analysis of volatile components from Ziziphora taurica subsp. taurica by steam distillation, superheated-water extraction, and direct thermal desorption with GCxGC-TOFMS. |
| PubMed: | Monoterpene metabolism. Cloning, expression, and characterization of (-)-isopiperitenol/(-)-carveol dehydrogenase of peppermint and spearmint. |
| PubMed: | Essential oil composition of aerial parts of Angelica glauca growing wild in North-West Himalaya (India). |
| PubMed: | Volatile chemicals identified in extracts from newly hybrid citrus, dekopon (Shiranuhi mandarin Suppl. J.). |
| PubMed: | Effects of storage conditions on the composition of Citrus tamurana Hort. ex Tanaka (hyuganatsu) essential oil. |
| PubMed: | Metabolism of (+)- and (-)-limonenes to respective carveols and perillyl alcohols by CYP2C9 and CYP2C19 in human liver microsomes. |
| PubMed: | Hydroxylation of specifically deuterated limonene enantiomers by cytochrome p450 limonene-6-hydroxylase reveals the mechanism of multiple product formation. |
| PubMed: | Sex differences in the metabolism of (+)- and (-)-limonene enantiomers to carveol and perillyl alcohol derivatives by cytochrome p450 enzymes in rat liver microsomes. |
| PubMed: | Biotransformation of D-limonene to (+) trans-carveol by toluene-grown Rhodococcus opacus PWD4 cells. |
| PubMed: | Percutaneous absorption of the montoterperne carvone: implication of stereoselective metabolism on blood levels. |
| PubMed: | Characterization of the odor-active volatiles in citrus Hyuganatsu (Citrus tamurana Hort. ex Tanaka). |
| PubMed: | Hydroxylation of limonene enantiomers and analogs by recombinant (-)-limonene 3- and 6-hydroxylases from mint (Mentha) species: evidence for catalysis within sterically constrained active sites. |
| PubMed: | Functional expression of regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha spp.) in Escherichia coli and saccharomyces cerevisiae. |
| PubMed: | Regiospecific cytochrome P450 limonene hydroxylases from mint (Mentha) species: cDNA isolation, characterization, and functional expression of (-)-4S-limonene-3-hydroxylase and (-)-4S-limonene-6-hydroxylase. |
| PubMed: | Effects of R-(+)-limonene on submerged cultures of the terpene transforming basidiomycete Pleurotus sapidus. |
| PubMed: | Biosynthesis of the monoterpenes limonene and carvone in the fruit of caraway. I. Demonstration Of enzyme activities and their changes with development |
| PubMed: | Cytochrome P450 limonene hydroxylases of Mentha species. |
| PubMed: | Biochemical characterization of a spearmint mutant that resembles peppermint in monoterpene content. |
| PubMed: | Monoterpene biosynthesis: specificity of the hydroxylations of (-)-limonene by enzyme preparations from peppermint (Mentha piperita), spearmint (Mentha spicata), and perilla (Perilla frutescens) leaves. |
| PubMed: | Biochemical and Histochemical Localization of Monoterpene Biosynthesis in the Glandular Trichomes of Spearmint (Mentha spicata). |
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