Articles:
cholest-5-en-3b-ol dodecanoate
Notes:
Cholesteryl lauric acid is a cholesteryl ester. A cholesteryl ester is an ester of cholesterol. Fatty acid esters of cholesterol constitute about two-thirds of the cholesterol in the plasma. Cholesterol is a sterol (a combination steroid and alcohol) and a lipid found in the cell membranes of all body tissues, and transported in the blood plasma of all animals. The accumulation of cholesterol esters in the arterial intima (the innermost layer of an artery, in direct contact with the flowing blood) is a characteristic feature of atherosclerosis. Atherosclerosis is a disease affecting arterial blood vessels. It is a chronic inflammatory response in the walls of arteries, in large part to the deposition of lipoproteins (plasma proteins that carry cholesterol and triglycerides). Lauric acid greatly increases total cholesterol, but much of its effect is on HDL cholesterol. Consequently, oils rich in lauric acid decrease the ratio of total to HDL cholesterol. (PMID: 12716665, 8644684, 10030391) [HMDB]
| CAS Number: | 1908-11-8 |  3D/inchi
|
| Other(deleted CASRN): | 137170-90-2 | |
| ECHA EINECS - REACH Pre-Reg: | 217-613-6 | |
| FDA UNII: | 3CV9B999WH | |
| Nikkaji Web: | J151.254D | |
| MDL: | MFCD00021142 | |
| XlogP3-AA: | 14.30 (est) | |
| Molecular Weight: | 568.96936000 | |
| Formula: | C39 H68 O2 | |
| NMR Predictor: | Predict (works with chrome or firefox) | |
Category: information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
| Google Scholar: | Search |
| Google Books: | Search |
| Google Scholar: with word "volatile" | Search |
| Google Scholar: with word "flavor" | Search |
| Google Scholar: with word "odor" | Search |
| Google Patents: | Search |
| US Patents: | Search |
| EU Patents: | Search |
| Pubchem Patents: | Search |
| PubMed: | Search |
| NCBI: | Search |
Physical Properties:
| Assay: | 95.00 to 100.00 % |
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 609.37 °C. @ 760.00 mm Hg (est) |
| Flash Point: | 611.00 °F. TCC ( 321.50 °C. ) (est) |
| logP (o/w): | 15.637 (est) |
| Soluble in: | |
| water, 7.827e-011 mg/L @ 25 °C (est) | |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). | |
Cosmetic Information:
| None found |
Suppliers:
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| Cholesteryl Laurate |
| Sigma-Aldrich: Sigma |
| For experimental / research use only. |
| Cholesteryl dodecanoate ≥98% (HPLC; detection at 205 nm) |
Safety Information:
| Preferred SDS: View | |
| Hazards identification | |
| Classification of the substance or mixture | |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) | |
| None found. | |
| GHS Label elements, including precautionary statements | |
| Pictogram | |
| Hazard statement(s) | |
| None found. | |
| Precautionary statement(s) | |
| None found. | |
| Oral/Parenteral Toxicity: | |
| Not determined | |
| Dermal Toxicity: | |
| Not determined | |
| Inhalation Toxicity: | |
| Not determined | |
Safety in Use Information:
| Category: | information only not used for fragrances or flavors | ||
| Recommendation for cholesteryl laurate usage levels up to: | |||
| not for fragrance use. | |||
| Recommendation for cholesteryl laurate flavor usage levels up to: | |||
| not for flavor use. | |||
Safety References:
| EPI System: | View |
| AIDS Citations: | Search |
| Cancer Citations: | Search |
| Toxicology Citations: | Search |
| EPA Substance Registry Services (TSCA): | 1908-11-8 |
| EPA ACToR: | Toxicology Data |
| EPA Substance Registry Services (SRS): | Registry |
| Laboratory Chemical Safety Summary : | 102182 |
| National Institute of Allergy and Infectious Diseases: | Data |
| WGK Germany: | 3 |
| [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] dodecanoate | |
| Chemidplus: | 0001908118 |
References:
| [(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] dodecanoate | |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 102182 |
| Pubchem (sid): | 135059176 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| KEGG (GenomeNet): | C02530 |
| HMDB (The Human Metabolome Database): | HMDB02262 |
| FooDB: | FDB022932 |
| ChemSpider: | View |
Potential Blenders and core components note
| None Found | ||
Potential Uses:
| None Found |
Occurrence (nature, food, other): note
| not found in nature |
Synonyms:
| cholest-5-en-3-beta-yl laurate | |
| cholest-5-en-3-yl laurate | |
| (3b)- | cholest-5-en-3-yl laurate |
| cholest-5-en-3b-ol dodecanoate | |
| cholest-5-en-3beta-ol dodecanoate | |
| cholesterol laurate | |
| cholesterol, laurate (8CI) | |
| cholesteryl dodecanoate | |
| cholesteryllaurate | |
| [(3S,8S,9S,10R,13R,14S,17R)-10,13- | dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] dodecanoate |
| dodecanoic acid cholesteryl ester | |
| dodecanoic acid, (3b)-cholest-5-en-3-yl ester | |
| dodecanoic acid, cholesteryl ester |