lauryl sucrose
alpha-D-glucopyranoside, beta-D-fructofuranosyl, dodecanoate
 
Notes:
None found
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      Product(s):
      37266-93-6 Sucrose dodecanoate
       
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CAS Number: 37266-93-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg: 253-432-9
Molecular Weight: 542.62022000
Formula: C24 H46 O13
NMR Predictor: Predict (works with chrome or firefox)
Category: emollients, emulsifiers, surfactants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 697.10 °C. @ 760.00 mm Hg (est)
Flash Point: 708.00 °F. TCC ( 375.40 °C. ) (est)
logP (o/w): -3.484 (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: skin conditioning
skin conditioning - emollient
surfactants
surfactant - emulsifying
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Suppliers:
BOC Sciences
For experimental / research use only.
Sucrose dodecanoate
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: emollients, emulsifiers, surfactants
Recommendation for lauryl sucrose usage levels up to:
 not for fragrance use.
 
Recommendation for lauryl sucrose flavor usage levels up to:
 not for flavor use.
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Safety References:
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 162254
National Institute of Allergy and Infectious Diseases: Data
 (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;dodecanoic acid
Chemidplus: 0037266936
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References:
 (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;dodecanoic acid
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 162254
Pubchem (sid): 135117984
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
HMDB (The Human Metabolome Database): Search
ChemSpider: View
EFSA Update of results on the monitoring of furan levels in food: Read Report
EFSA Previous report: Results on the monitoring of furan levels in food: Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 not found in nature
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Synonyms:
(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;dodecanoic acid
alpha-delta-glucopyranoside beta-delta-fructofuranosyl dodecanoate
alpha-D-glucopyranoside, beta-D-fructofuranosyl, dodecanoate
 sucrose laurate
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Articles:
PubMed: Effects of propylene glycol alginate and sucrose esters on the physicochemical properties of modified starch-stabilized beverage emulsions.
PubMed: Efficient delivery and distribution in skin of chlorogenic acid and resveratrol induced by microemulsion using sucrose laurate.
PubMed: Evaluation of Shirasu Porous Glass (SPG) membrane emulsification for the preparation of colloidal lipid drug carrier dispersions.
PubMed: Elution strategies for reversed-phase high-performance liquid chromatography analysis of sucrose alkanoate regioisomers with charged aerosol detection.
PubMed: Application of quantitative (19) F nuclear magnetic resonance spectroscopy in tape-stripping experiments with natural microemulsions.
PubMed: Effects of selected polysorbate and sucrose ester emulsifiers on the physicochemical properties of astaxanthin nanodispersions.
PubMed: [Modelling of pecutaneous drug permeation and investigation of penetration enhancer effect].
PubMed: Natural microemulsions: formulation design and skin interaction.
PubMed: Preparation of nanoemulsions and solid lipid nanoparticles by premix membrane emulsification.
PubMed: Enhancement potential of sucrose laurate (L-1695) on intestinal absorption of water-soluble high molecular weight compounds.
PubMed: A combined approach of vesicle formulations and microneedle arrays for transcutaneous immunization against hepatitis B virus.
PubMed: Characterization of cephalexin loaded nonionic microemulsions.
PubMed: Head group effects on molecular packing in lamellar liquid crystals.
PubMed: Sugar ester J-1216 enhances percutaneous permeation of ionized lidocaine.
PubMed: [The applicability of sucrose laurate in hot-melt technology].
PubMed: Hydrolysis of fish oil by hyperactivated Rhizomucor miehei lipase immobilized by multipoint anion exchange.
PubMed: Applicability of sucrose laurate as surfactant in solid dispersions prepared by melt technology.
PubMed: Full enzymatic hydrolysis of commercial sucrose laurate by immobilized-stabilized derivatives of lipase from Thermomyces lanuginosa.
PubMed: Investigating the stability of the nonionic surfactants tocopheryl polyethylene glycol succinate and sucrose laurate by HPLC-MS, DAD, and CAD.
PubMed: Effects of non-ionic surfactants on cytochrome P450-mediated metabolism in vitro.
PubMed: Inactivation of Bacillus amyloliquefaciens spores by a combination of sucrose laurate and pressure-assisted thermal processing.
PubMed: Effects of non-ionic surfactants on in vitro triglyceride digestion and their susceptibility to digestion by pancreatic enzymes.
PubMed: Solubilization of poorly water-soluble drugs by mixed micelles based on hydrogenated phosphatidylcholine.
PubMed: Formulation and characterization of microemulsions based on mixed nonionic surfactants and peppermint oil.
PubMed: Mixed micelle formation with phosphatidylcholines: the influence of surfactants with different molecule structures.
PubMed: Mathematical modeling of pH-surfactant-mediated solubilization of nimesulide.
PubMed: Preparation and characterization of diphtheria toxoid-loaded elastic vesicles for transcutaneous immunization.
PubMed: Glucosylation of sucrose laurate with cyclodextrin glucanotransferase.
PubMed: Effect of high hydrostatic pressure on four genotypes of F-specific RNA bacteriophages.
PubMed: Cellular uptake of carotenoid-loaded oil-in-water emulsions in colon carcinoma cells in vitro.
PubMed: Effect of sucrose fatty acid esters on transdermal permeation of lidocaine and ketoprofen.
PubMed: PFGSE-NMR study of the self-diffusion of sucrose fatty acid monoesters in water.
PubMed: Transdermal delivery of pergolide from surfactant-based elastic and rigid vesicles: characterization and in vitro transport studies.
PubMed: Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements.
PubMed: Bacterial spore inhibition and inactivation in foods by pressure, chemical preservatives, and mild heat.
PubMed: Elasticity of vesicles affects hairless mouse skin structure and permeability.
PubMed: Feasibility of using food-grade additives to control the growth of Clostridium perfringens.
PubMed: Sucrose laurate gels as a percutaneous delivery system for oestradiol in rabbits.
PubMed: Micellization and solubilization behavior of sucrose laurate, a new pharmaceutical excipient.
PubMed: Effects of the aggregation state of amphotericin B on its toxicity to mice.
PubMed: The effect of surfactants on the aggregation state of amphotericin B.
PubMed: Stimulation of lymphoproliferation by sucrose esters.
PubMed: beta-Glucoside Activators of Mung Bean UDP-Glucose: beta-Glucan Synthase : II. Comparison of Effects of an Endogenous beta-Linked Glucolipid with Synthetic n-Alkyl beta-d-Monoglucopyranosides.
PubMed: Structural properties of the D1 and surrounding photosystem II polypeptides as revealed by their interaction with cross-linking reagents.
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