coronafacic acid
(3aS,6R,7aS)-6-ethyl-1-oxo-2,3,3a,6,7,7a-hexahydro-1H-indene-4-carboxylic acid
 
Notes:
a polyketide that is coupled to coronamic acid by coronafacate ligase to form coronatine.
Synonyms   Articles   Notes   Search
CAS Number: 62251-98-3Picture of molecule3D/inchi
Nikkaji Web: J53.003D
XlogP3-AA: 1.50 (est)
Molecular Weight: 208.25712000
Formula: C12 H16 O3
NMR Predictor: Predict (works with chrome or firefox)
Category: information only not used for fragrances or flavors
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
Synonyms   Articles   Notes   Search   Top
Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 375.40 °C. @ 760.00 mm Hg (est)
Flash Point: 383.00 °F. TCC ( 195.00 °C. ) (est)
logP (o/w): 1.850 (est)
Soluble in:
 water, 1922 mg/L @ 25 °C (est)
Synonyms   Articles   Notes   Search   Top
Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
Synonyms   Articles   Notes   Search   Top
Cosmetic Information:
None found
Synonyms   Articles   Notes   Search   Top
Suppliers:
 None found
Synonyms   Articles   Notes   Search   Top
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Synonyms   Articles   Notes   Search   Top
Safety in Use Information:
Category: information only not used for fragrances or flavors
Recommendation for coronafacic acid usage levels up to:
 not for fragrance use.
 
Recommendation for coronafacic acid flavor usage levels up to:
 not for flavor use.
Synonyms   Articles   Notes   Search   Top
Safety References:
EPI System: View
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 114969
National Institute of Allergy and Infectious Diseases: Data
 (3aS,6R,7aS)-6-ethyl-1-oxo-2,3,3a,6,7,7a-hexahydroindene-4-carboxylic acid
Chemidplus: 0062251983
Synonyms   Articles   Notes   Search   Top
References:
 (3aS,6R,7aS)-6-ethyl-1-oxo-2,3,3a,6,7,7a-hexahydroindene-4-carboxylic acid
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 114969
Pubchem (sid): 135072647
Synonyms   Articles   Notes   Search   Top
Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEBI: View
KEGG (GenomeNet): C15765
HMDB (The Human Metabolome Database): Search
ChemSpider: View
Wikipedia: View
Synonyms   Articles   Notes   Search   Top
Potential Blenders and core components note
 
None Found
 
Synonyms   Articles   Notes   Search   Top
Potential Uses:
None Found
Synonyms   Articles   Notes   Search   Top
Occurrence (nature, food, other): note
 not found in nature
Synonyms   Articles   Notes   Search   Top
Synonyms:
(3aS,6R,7aS)-6-ethyl-1-oxo-2,3,3a,6,7,7a-hexahydro-1H-indene-4-carboxylic acid
(3aS,6R,7aS)-6-ethyl-1-oxo-2,3,3a,6,7,7a-hexahydroindene-4-carboxylic acid
6-ethyl-2,3,3as,6R,7,7as-hexahydro-1-oxo-1H-indene-4-carboxylic acid
1H-indene-4-Carboxylic acid, 6-ethyl-2,3,3a,6,7,7a-hexahydro-1-oxo-, (3aS-(3alpha,6beta,7aalpha))-
1H-indene-4-Carboxylic acid, 6-ethyl-2,3,3a,6,7,7a-hexahydro-1-oxo-, (3aS,6R,7aS)-
Synonyms   Articles   Notes   Search   Top
Articles:
PubMed: Pseudomonas syringae pv. tomato DC3000 CmaL (PSPTO4723), a DUF1330 family member, is needed to produce L-allo-isoleucine, a precursor for the phytotoxin coronatine.
PubMed: Inactivation of PbTopo IIIβ causes hyper-excision of the Pathogenicity Island HAI2 resulting in reduced virulence of Pectobacterium atrosepticum.
PubMed: Synthesis of coronafacic acid via TBAF-assisted elimination of the mesylate and its conversion to the isoleucine conjugate.
PubMed: Azido-coronatine: a useful platform for "click chemistry"-mediated probe synthesis for bioorganic studies.
PubMed: Streptomyces scabies 87-22 contains a coronafacic acid-like biosynthetic cluster that contributes to plant-microbe interactions.
PubMed: Simple and rapid capillary zone electrophoresis method for the detection of coronamic acid, a precursor to the Pseudomonas syringae phytotoxin coronatine.
PubMed: Synthesis of (+)-coronafacic acid.
PubMed: Cascade reactions during coronafacic acid biosynthesis: elongation, cyclization, and functionalization during Cfa7-catalyzed condensation.
PubMed: The phytotoxin coronatine contributes to pathogen fitness and is required for suppression of salicylic acid accumulation in tomato inoculated with Pseudomonas syringae pv. tomato DC3000.
PubMed: Expedient stereoselective synthesis of coronafacic acid through intramolecular Diels-Alder cyclization.
PubMed: The phytotoxin coronatine from Pseudomonas syringae pv. tomato DC3000 functions as a virulence factor and influences defence pathways in edible brassicas.
PubMed: CorR regulates multiple components of virulence in Pseudomonas syringae pv. tomato DC3000.
PubMed: The Pseudomonas syringae phytotoxin coronatine promotes virulence by overcoming salicylic acid-dependent defences in Arabidopsis thaliana.
PubMed: The phytotoxin coronatine and methyl jasmonate impact multiple phytohormone pathways in tomato.
PubMed: Characterization of Cfa1, a monofunctional acyl carrier protein involved in the biosynthesis of the phytotoxin coronatine.
PubMed: Identification and characterization of a well-defined series of coronatine biosynthetic mutants of Pseudomonas syringae pv. tomato DC3000.
PubMed: Characterization of CmaA, an adenylation-thiolation didomain enzyme involved in the biosynthesis of coronatine.
PubMed: [6-endo-trig mode cyclization to a hydrindanone using samarium (II) iodide].
PubMed: Control of temperature-responsive synthesis of the phytotoxin coronatine in Pseudomonas syringae by the unconventional two-component system CorRPS.
PubMed: Analysis of the enzymatic domains in the modular portion of the coronafacic acid polyketide synthase.
PubMed: Interactions of Pseudomonas syringae pv. glycinea with host and nonhost plants in relation to temperature and phytotoxin synthesis.
PubMed: Biosynthesis of the Pseudomonas polyketide coronafacic acid requires monofunctional and multifunctional polyketide synthase proteins.
PubMed: Characterization of CorR, a transcriptional activator which is required for biosynthesis of the phytotoxin coronatine.
PubMed: Analysis of genes involved in biosynthesis of coronafacic acid, the polyketide component of the phytotoxin coronatine.
PubMed: Growth phase and temperature influence promoter activity, transcript abundance, and protein stability during biosynthesis of the Pseudomonas syringae phytotoxin coronatine.
PubMed: Expression and analysis of coronafacate ligase, a thermoregulated gene required for production of the phytotoxin coronatine in Pseudomonas syringae.
PubMed: Use of Tn5-gusA5 to investigate environmental and nutritional effects on gene expression in the coronatine biosynthetic gene cluster of Pseudomonas syringae pv. glycinea.
PubMed: Characterisation of genes involved in biosynthesis of coronafacic acid, the polyketide component of the phytotoxin coronatine.
PubMed: Structure-activity relationships of cyclopentane analogs of jasmonic acid for induced responses of canola seedlings,Brassica napus L.
PubMed: Characterization and transcriptional analysis of the gene cluster for coronafacic acid, the polyketide component of the phytotoxin coronatine.
PubMed: Sequence, expression and transcriptional analysis of the coronafacate ligase-encoding gene required for coronatine biosynthesis by Pseudomonas syringae.
PubMed: Cloning and expression of genes required for coronamic Acid (2-ethyl-1-aminocyclopropane 1-carboxylic Acid), an intermediate in the biosynthesis of the phytotoxin coronatine.
PubMed: The Pseudomonas phytotoxin coronatine mimics octadecanoid signalling molecules of higher plants.
PubMed: Characterization of the genes controlling the biosynthesis of the polyketide phytotoxin coronatine including conjugation between coronafacic and coronamic acid.
PubMed: Physical and functional characterization of the gene cluster encoding the polyketide phytotoxin coronatine in Pseudomonas syringae pv. glycinea.
PubMed: Plasmid-mediated production of the phytotoxin coronatine in Pseudomonas syringae pv. tomato.
PubMed: Stimulation of ethylene production in bean leaf discs by the pseudomonad phytotoxin coronatine.
Synonyms   Articles   Notes   Search   Top
Please share your Comments.
Email Address:
 
 
 
 
Top of Page Home
Copyright © 1980-2020 Perflavory ™ Disclaimer Privacy Policy