pulvinic acid
benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, (E)- (9CI)
 
Notes:
None found
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CAS Number: 26548-70-9Picture of molecule3D/inchi
FDA UNII: Q17C0F3Z5W
Nikkaji Web: J68.365E
XlogP3-AA: 2.70 (est)
Molecular Weight: 308.28964000
Formula: C18 H12 O5
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: herbicides / pesticides
 
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Physical Properties:
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Boiling Point: 544.39 °C. @ 760.00 mm Hg (est)
Flash Point: 399.00 °F. TCC ( 203.90 °C. ) (est)
logP (o/w): 2.945 (est)
Soluble in:
 water, 91.16 mg/L @ 25 °C (est)
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Organoleptic Properties:
 
Odor and/or flavor descriptions from others (if found).
 
 
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Cosmetic Information:
None found
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50  500 mg/kg
Acta Pharmacologica et Toxicologica. Vol. 2, Pg. 109, 1946.

oral-mouse LDLo  1000 mg/kg
National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 30, 1953.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: herbicides / pesticides
Recommendation for pulvinic acid usage levels up to:
 not for fragrance use.
 
Recommendation for pulvinic acid flavor usage levels up to:
 not for flavor use.
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Safety References:
EPI System: View
AIDS Citations: Search
Cancer Citations: Search
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EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 54682513
National Institute of Allergy and Infectious Diseases: Data
 (2E)-2-(3-hydroxy-5-oxo-4-phenylfuran-2-ylidene)-2-phenylacetic acid
Chemidplus: 0026548709
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References:
 (2E)-2-(3-hydroxy-5-oxo-4-phenylfuran-2-ylidene)-2-phenylacetic acid
NIST Chemistry WebBook: Search Inchi
Pubchem (cid): 54682513
Pubchem (sid): 135074522
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Other Information:
(IUPAC): Atomic Weights of the Elements 2011 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
CHEMBL: View
HMDB (The Human Metabolome Database): Search
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
EFSA Update of results on the monitoring of furan levels in food: Read Report
EFSA Previous report: Results on the monitoring of furan levels in food: Read Report
EFSA Report of the CONTAM Panel on provisional findings on furan in food: Read Report
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 found in nature
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Synonyms:
 acetic acid, (3-hydroxy-5-oxo-4-phenyl-2(5H)-furylidene)phenyl-
 benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, (E)- (9CI)
delta(sup 2(5H),alpha)-furanacetic acid, 3-hydroxy-5-oxo-alpha,4-diphenyl-
2,4-hexadienedioic acid, 3,4-dihydroxy-2,5-diphenyl-, gamma-lactone
(E)-alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene) benzene acetic acid
(2E)-2-(3-hydroxy-5-oxo-4-phenylfuran-2-ylidene)-2-phenylacetic acid
 pulvic acid
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Articles:
PubMed: Development of models for prediction of the antioxidant activity of derivatives of natural compounds.
PubMed: UV-protectant metabolites from lichens and their symbiotic partners.
PubMed: Design and synthesis of new antioxidants predicted by the model developed on a set of pulvinic acid derivatives.
PubMed: Synthesis and radioprotective properties of pulvinic acid derivatives.
PubMed: Synthesis and antioxidant properties of pulvinic acids analogues.
PubMed: Norbadione a: kinetics and thermodynamics of cesium uptake in aqueous and alcoholic media.
PubMed: Chemical constituents of the lichen, Candelaria concolor: a complete NMR and chemical degradative investigation.
PubMed: In vitro inhibitory effects of pulvinic acid derivatives isolated from Chinese edible mushrooms, Boletus calopus and Suillus bovinus, on cytochrome P450 activity.
PubMed: Evaluation of antioxidant properties of monoaromatic derivatives of pulvinic acids.
PubMed: Synthesis of pulvinic derivatives via TBAF-mediated regioselective opening of an unsymmetrical monoaromatic pulvinic dilactone.
PubMed: Dissociation and metal-binding characteristics of yellow lichen substances suggest a relationship with site preferences of lichens.
PubMed: Mollusc grazing may constrain the ecological niche of the old forest lichen Pseudocyphellaria crocata.
PubMed: Conformational and Cs+ complexation properties of norbadione-A: a molecular modeling study.
PubMed: Interactions of sterile-cultured lichen-forming ascomycetes with asbestos fibres.
PubMed: Pinastric acid revisited: a complete NMR and X-ray structure assignment.
PubMed: Dichlorinated pulvinic acid derivative from a Malaysian Scleroderma sp.
PubMed: Pulvinones as bacterial cell wall biosynthesis inhibitors.
PubMed: High-throughput evaluation of antioxidant and pro-oxidant activities of polyphenols with thymidine protection assays.
PubMed: Raman spectroscopy of hot desert, high altitude epilithic lichens.
PubMed: Uncatalyzed reaction of silyl ketene acetals with oxalyl chloride: a straightforward preparation of symmetrical pulvinic acids.
PubMed: Unusual pulvinic acid dimers from the common fungi Scleroderma citrinum (common earthball) and Chalciporus piperatus (peppery bolete).
PubMed: Norbadione A: synthetic approach to the bis(pulvinic acid) moiety and cesium-complexation studies.
PubMed: Simple method for reversed-phase high-performance liquid chromatographic analysis of fungal pigments in fruit-bodies of Boletales (Fungi).
PubMed: Pharmaceutically relevant metabolites from lichens.
PubMed: [Mushroom pigments. 3. Xerocomic acid and gomphidic acid, 2 chemotaxonomically interesting pulvinic acid derivatives from Gomphidius glutinosus (Schff) Fr].
PubMed: [New pulvinic acid derivatives from Xerocomus chrysenteron (Bull. ex St. Amans) Quel. and studies on the question of the occurrence of anthraquinone pigments in boletaceae].
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